Search Results - "Coupal, Louis"
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Persistence rates of abatacept and TNF inhibitors used as first or second biologic DMARDs in the treatment of rheumatoid arthritis: 9 years of experience from the Rhumadata® clinical database and registry
Published in Arthritis research & therapy (06-06-2019)“…Treatment persistence is an important consideration when selecting a therapy for chronic conditions such as rheumatoid arthritis (RA). We assessed the…”
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Discontinuation of tofacitinib and TNF inhibitors in patients with rheumatoid arthritis: analysis of pooled data from two registries in Canada
Published in BMJ open (06-03-2023)“…ObjectivesThe similarity in retention of tumour necrosis factor inhibitors (TNFi) and tofacitinib (TOFA) was previously reported separately by the Ontario Best…”
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3
Bayesian estimation of disease prevalence and the parameters of diagnostic tests in the absence of a gold standard
Published in American journal of epidemiology (01-02-1995)“…It is common in population screening surveys or in the investigation of new diagnostic tests to have results from one or more tests investigating the same…”
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Estimating the Benefits of Patient and Physician Adherence to Cardiovascular Prevention Guidelines: The MyHealthCheckup Survey
Published in Canadian journal of cardiology (01-03-2011)“…Abstract Background The management of cardiovascular risk factors such as hypertension and dyslipidemia is poorly described in many communities, and the…”
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Preventing cardiovascular disease among Canadians: Is the treatment of hypertension or dyslipidemia cost-effective?
Published in Canadian journal of cardiology (01-12-2008)“…Background and objectives The direct health care costs associated with treating hypertension and dyslipidemia continue to grow in most western countries,…”
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How Cost-Effective Is the Treatment of Dyslipidemia in Patients With Diabetes but Without Cardiovascular Disease?
Published in Diabetes care (01-01-2001)“…How Cost-Effective Is the Treatment of Dyslipidemia in Patients With Diabetes but Without Cardiovascular Disease? Steven A. Grover , MD, MPA, FRCPC , Louis…”
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Preventing cardiovascular disease among Canadians: What are the potential benefits of treating hypertension or dyslipidemia?
Published in Canadian journal of cardiology (01-05-2007)“…Background Treatments for hypertension and dyslipidemia to prevent the development of cardiovascular disease compete for the same finite number of health care…”
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Determining the cost-effectiveness of preventing cardiovascular disease: Are estimates calculated over the duration of a clinical trial adequate?
Published in Canadian journal of cardiology (01-04-2008)“…Background Economic analyses of randomized clinical trials often focus only on the results that are observed during the study. However, for many preventive…”
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A Real-World Analysis on Weather Variation Disease Activity and Patient Reported Outcomes in Psoriatic Arthritis
Published in Journal of rheumatology (15-09-2024)“…Anecdotally, patients with inflammatory articular diseases (IAD) such as psoriatic arthritis (PsA) report weather changes in their symptoms. The objective is…”
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Cost-utility analysis of second-line therapy with rituximab compared to tumour necrosis factor inhibitors in rheumatoid arthritis
Published in Current medical research and opinion (02-01-2021)“…To compare direct costs and treatment utility associated with the second-line therapy with rituximab and tumour necrosis factor inhibitors (TNFis) (adalimumab,…”
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Development and clinical validation of an in situ biopsy-based multimarker assay for risk stratification in prostate cancer
Published in Clinical cancer research (01-06-2015)“…Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are…”
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Residual Disease Activity in Canadian Patients With Psoriatic Arthritis Treated With Advanced Therapies: Results From a Multiregistry Analysis (UNISON-PsA)
Published in Journal of rheumatology (01-05-2024)“…Objective Although patient outcomes in psoriatic arthritis (PsA) have improved with the advent of advanced therapies, there remains a high unmet need to treat…”
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Which advanced treatment should be used following the failure of a first-line anti-TNF in patients with rheumatoid arthritis? 15 years of evidence from the Quebec registry RHUMADATA
Published in Rheumatology (Oxford, England) (03-06-2024)“…Since 2000, advanced therapies (AT) have revolutionized the treatment of moderate to severe rheumatoid arthritis (RA). Randomized control trials as well as…”
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Hypomagnesemia During Teriparatide Treatment in Osteoporosis: Incidence and Determinants
Published in Journal of bone and mineral research (01-08-2018)“…ABSTRACT In our clinical experience, we have encountered patients who developed hypomagnesemia after the introduction of teriparatide. Some trials have…”
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Heterogeneity in Patient Characteristics and Differences in Treatment Across 4 Canadian Rheumatoid Arthritis Cohorts
Published in Journal of rheumatology (01-01-2022)“…To compare clinical characteristics and treatment of patients with rheumatoid arthritis (RA) across 4 Canadian cohorts. The 4 longitudinal cohorts included the…”
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Residual Disease Activity In Canadian Patients With Psoriatic Arthritis (PsA) Treated With Advanced Therapies: Results From A Multi-Registry Analysis (UNISON-PsA)
Published in Journal of rheumatology (15-02-2024)“…Although patient outcomes in psoriatic arthritis (PsA) have improved with the advent of advanced therapies, there remains a high unmet need to treat residual…”
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Discussing Coronary Risk with Patients to Improve Blood Pressure Treatment: Secondary Results from the CHECK-UP Study
Published in Journal of general internal medicine : JGIM (01-01-2009)“…Objectives Hypertension is common among patients with dyslipidemia but is often poorly treated. The objective of this analysis was to evaluate how a decision…”
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Distinguishing aggressive versus nonaggressive prostate cancer using a novel prognostic proteomics biopsy test, ProMark
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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Impact of dyslipidemia associated with highly active antiretroviral therapy (HAART) on cardiovascular risk and life expectancy
Published in The American journal of cardiology (01-03-2005)“…We investigated the effect of dyslipidemia associated with highly active antiretroviral therapy on cardiovascular risk and life expectancy among patients who…”
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Treating Osteoarthritis With Cyclooxygenase-2–Specific Inhibitors: What Are the Benefits of Avoiding Blood Pressure Destabilization?
Published in Hypertension (Dallas, Tex. 1979) (01-01-2005)“…Osteoarthritis and hypertension are highly prevalent among older Americans. Anti-inflammatory medications can destabilize blood pressure control. We estimated…”
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