Search Results - "Counter, C.M."

Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression by Wang, Cun-Yu, Shi, Songtao, Gronthos, Stan, Chen, Shaoqiong, Reddi, Anand, Counter, Christopher M, Robey, Pamela G

“…Human postnatal bone marrow stromal stem cells (BMSSCs) have a limited life-span and progressively lose their stem cell properties during ex vivo expansion…”
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Ral activation promotes melanomagenesis by Zipfel, P A, Brady, D C, Kashatus, D F, Ancrile, B D, Tyler, D S, Counter, C M

“…Up to one-third of human melanomas are characterized by an oncogenic mutation in the gene encoding the small guanosine triphosphatase (GTPase) NRAS . Ras…”
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The catalytic subunit of yeast telomerase by Counter, C.M, Meyerson, M, Eaton, E.N, Weinberg, R.A

“…Telomerase is an RNA-directed DNA polymerase, composed of RNA and protein subunits, that replicates the telomere ends of linear eukaryotic chromosomes. Using a…”
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Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity by Counter, C.M., Avilion, A.A., LeFeuvre, C.E., Stewart, N.G., Greider, C.W., Harley, C.B., Bacchetti, S.

“…Loss of telomeric DNA during cell proliferation may play a role in ageing and cancer. Since telomeres permit complete replication of eukaryotic chromosomes and…”
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Telomerase, cell immortality, and cancer by Harley, C B, Kim, N W, Prowse, K R, Weinrich, S L, Hirsch, K S, West, M D, Bacchetti, S, Hirte, H W, Counter, C M, Greider, C W

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