Search Results - "Coulter, Sophie M."
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Ultrashort Peptide Hydrogels Display Antimicrobial Activity and Enhance Angiogenic Growth Factor Release by Dental Pulp Stem/Stromal Cells
Published in Materials (27-04-2021)“…Recent studies on peptide hydrogels have shown that ultrashort peptides (<8 amino acids) can self-assemble into hydrogels. Ultrashort peptides can be designed…”
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Investigating the In Vivo Antimicrobial Activity of a Self-Assembling Peptide Hydrogel Using a Galleria mellonella Infection Model
Published in ACS omega (28-02-2019)“…Technological advances in protein biochemistry now enable researchers to modify the structure of peptides to enable them to possess self-assembling properties,…”
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Ultrashort Self-Assembling Peptide Hydrogel for the Treatment of Fungal Infections
Published in Gels (22-05-2018)“…The threat of antimicrobial resistance to society is compounded by a relative lack of new clinically effective licensed therapies reaching patients over the…”
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Unravelling the antimicrobial activity of peptide hydrogel systems: current and future perspectives
Published in Soft matter (15-09-2021)“…The use of hydrogels has garnered significant interest as biomaterial and drug delivery platforms for anti-infective applications. For decades antimicrobial…”
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Pharmaceutical Formulation and Characterization of Dipeptide Nanotubes for Drug Delivery Applications
Published in Macromolecular bioscience (01-07-2020)“…Peptide nanotubes are promising materials for a variety of biomedical applications with ultrashort (≤7 amino acids) forms providing particular promise for…”
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Self-assembling diphenylalanine peptide nanotubes selectively eradicate bacterial biofilm infection
Published in Acta biomaterialia (01-09-2018)“…[Display omitted] Biofilms present a major problem to industry and healthcare worldwide. Composed of a population of surface-attached microbial cells…”
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Metal Cross-Linked Supramolecular Gel Noodles: Structural Insights and Antibacterial Assessment
Published in Biomacromolecules (13-05-2024)“…Achieving precise control over gelator alignment and morphology is crucial for crafting tailored materials and supramolecular structures with distinct…”
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In Situ Forming, Enzyme-Responsive Peptoid-Peptide Hydrogels: An Advanced Long-Acting Injectable Drug Delivery System
Published in Journal of the American Chemical Society (07-08-2024)“…Long-acting drug delivery systems are promising platforms to improve patient adherence to medication by delivering drugs over sustained periods and removing…”
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Tuning the antimicrobial activity of low molecular weight hydrogels using dopamine autoxidation
Published in Chemical communications (Cambridge, England) (21-07-2020)“…We present a method to trigger the formation of dipeptide-based hydrogels by the simple addition of dopamine. Dopamine undergoes oxidation in air, reducing the…”
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Enzyme‐Triggered l‐α/d‐Peptide Hydrogels as a Long‐Acting Injectable Platform for Systemic Delivery of HIV/AIDS Drugs
Published in Advanced healthcare materials (01-07-2023)“…Eradicating HIV/AIDS by 2030 is a central goal of the World Health Organization. Patient adherence to complicated dosage regimens remains a key barrier. There…”
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Antibacterial and antibiofilm efficacy of synthetic polymyxin‐mimetic lipopeptides
Published in Peptide science (Hoboken, N.J.) (01-01-2021)“…The increasing emergence of multidrug‐resistant bacteria is a huge problem to society providing significant risks to public health. This has been further…”
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Enzyme‐Triggered l‐α/d‐Peptide Hydrogels as a Long‐Acting Injectable Platform for Systemic Delivery of HIV/AIDS Drugs (Adv. Healthcare Mater. 18/2023)
Published in Advanced healthcare materials (01-07-2023)“…HIV/AIDS Drugs In article 2203198, Garry Laverty and co‐workers develop a long‐acting injectable drug delivery implant composed of a short peptide sequence…”
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