Search Results - "Coulson, Rochelle L."

Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex by Coulson, Rochelle L., Yasui, Dag H., Dunaway, Keith W., Laufer, Benjamin I., Vogel Ciernia, Annie, Zhu, Yihui, Mordaunt, Charles E., Totah, Theresa S., LaSalle, Janine M.

“…Rhythmic oscillations of physiological processes depend on integrating the circadian clock and diurnal environment. DNA methylation is epigenetically…”
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R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation by Powell, Weston T., Coulson, Rochelle L., Gonzales, Michael L., Crary, Florence K., Wong, Spencer S., Adams, Sarrita, Ach, Robert A., Tsang, Peter, Yamada, Nazumi Alice, Yasui, Dag H., Chédin, Frédéric, LaSalle, Janine M.

“…Prader–Willi syndrome (PWS) and Angelman syndrome (AS) are oppositely imprinted autism-spectrum disorders with known genetic bases, but complex epigenetic…”
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Epigenetics of Circadian Rhythms in Imprinted Neurodevelopmental Disorders by Coulson, Rochelle L, LaSalle, Janine M

“…DNA sequence information alone cannot account for the immense variability between chromosomal alleles within diverse cell types in the brain, whether these…”
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Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes by Dunaway, Keith W., Islam, M. Saharul, Coulson, Rochelle L., Lopez, S. Jesse, Vogel Ciernia, Annie, Chu, Roy G., Yasui, Dag H., Pessah, Isaac N., Lott, Paul, Mordaunt, Charles, Meguro-Horike, Makiko, Horike, Shin-ichi, Korf, Ian, LaSalle, Janine M.

“…Rare variants enriched for functions in chromatin regulation and neuronal synapses have been linked to autism. How chromatin and DNA methylation interact with…”
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Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome by Coulson, Rochelle L., Frattini, Valentina, Moyer, Caitlin E., Hodges, Jennifer, Walter, Peter, Mourrain, Philippe, Zuo, Yi, Wang, Gordon X.

“…Fragile X syndrome (FXS) is caused by the loss of fragile X messenger ribonucleoprotein (FMRP), a translational regulator that binds the transcripts of…”
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Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches by Vogel Ciernia, Annie, Laufer, Benjamin I ., Dunaway, Keith W., Mordaunt, Charles E., Coulson, Rochelle L., Totah, Theresa S., Stolzenberg, Danielle S., Frahm, Jaime C., Singh-Taylor, Akanksha, Baram, Tallie Z., LaSalle, Janine M., Yasui, Dag H.

“…Augmented maternal care during the first postnatal week promotes life-long stress resilience and improved memory compared with the outcome of routine rearing…”
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Genome-wide association mapping in dogs enables identification of the homeobox gene, NKX2-8, as a genetic component of neural tube defects in humans by Safra, Noa, Bassuk, Alexander G, Ferguson, Polly J, Aguilar, Miriam, Coulson, Rochelle L, Thomas, Nicholas, Hitchens, Peta L, Dickinson, Peter J, Vernau, Karen M, Wolf, Zena T, Bannasch, Danika L

“…Neural tube defects (NTDs) is a general term for central nervous system malformations secondary to a failure of closure or development of the neural tube. The…”
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Sleep deficiency as a driver of cellular stress and damage in neurological disorders by Coulson, Rochelle L., Mourrain, Philippe, Wang, Gordon X.

“…Neurological disorders encompass an extremely broad range of conditions, including those that present early in development and those that progress slowly or…”
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The intersection of sleep and synaptic translation in synaptic plasticity deficits in neurodevelopmental disorders by Coulson, Rochelle L., Mourrain, Philippe, Wang, Gordon X.

“…Individuals with neurodevelopmental disorders experience persistent sleep deficits, and there is increasing evidence that sleep dysregulation is an underlying…”
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Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study by Zhu, Yihui, Mordaunt, Charles E, Yasui, Dag H, Marathe, Ria, Coulson, Rochelle L, Dunaway, Keith W, Jianu, Julia M, Walker, Cheryl K, Ozonoff, Sally, Hertz-Picciotto, Irva, Schmidt, Rebecca J, LaSalle, Janine M

“…DNA methylation acts at the interface of genetic and environmental factors relevant for autism spectrum disorder (ASD). Placenta, normally discarded at birth,…”
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Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN by Coulson, Rochelle L, Powell, Weston T, Yasui, Dag H, Dileep, Gayathri, Resnick, James, LaSalle, Janine M

“…Abstract Prader-Willi syndrome (PWS), an imprinted neurodevelopmental disorder characterized by metabolic, sleep and neuropsychiatric features, is caused by…”
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Cognitive deficits in the Snord116 deletion mouse model for Prader-Willi syndrome by Adhikari, Anna, Copping, Nycole A., Onaga, Beth, Pride, Michael C., Coulson, Rochelle L., Yang, Mu, Yasui, Dag H., LaSalle, Janine M., Silverman, Jill L.

“…•A lack of the gene cluster SNORD116 may be responsible for some aspects of PWS.•Heterozygous Snord116 mutation mice had learning and memory deficits in three…”
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A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure by Powell, Weston T, Coulson, Rochelle L, Crary, Florence K, Wong, Spencer S, Ach, Robert A, Tsang, Peter, Alice Yamada, N, Yasui, Dag H, Lasalle, Janine M

“…Prader-Willi syndrome (PWS), a genetic disorder of obesity, intellectual disability and sleep abnormalities, is caused by loss of non-coding RNAs on paternal…”
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Genome-Wide Association Mapping in Dogs Enables Identification of the Homeobox Gene, NKX2-8, as a Genetic Component of Neural Tube Defects in Humans: e1003646 by Safra, Noa, Bassuk, Alexander G, Ferguson, Polly J, Aguilar, Miriam, Coulson, Rochelle L, Thomas, Nicholas, Hitchens, Peta L, Dickinson, Peter J, Vernau, Karen M, Wolf, Zena T, Bannasch, Danika L

“…Neural tube defects (NTDs) is a general term for central nervous system malformations secondary to a failure of closure or development of the neural tube. The…”
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