Search Results - "Coukos, Georges"

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance by Martins, Filipe, Sofiya, Latifyan, Sykiotis, Gerasimos P., Lamine, Faiza, Maillard, Michel, Fraga, Montserrat, Shabafrouz, Keyvan, Ribi, Camillo, Cairoli, Anne, Guex-Crosier, Yan, Kuntzer, Thierry, Michielin, Olivier, Peters, Solange, Coukos, Georges, Spertini, Francois, Thompson, John A., Obeid, Michel

“…Immune-checkpoint inhibitors (ICIs), including anti-cytotoxic T lymphocyte antigen 4 (CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell…”
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New therapeutic perspectives to manage refractory immune checkpoint-related toxicities by Martins, Filipe, Sykiotis, Gerasimos P, Maillard, Michel, Fraga, Montserrat, Ribi, Camillo, Kuntzer, Thierry, Michielin, Olivier, Peters, Solange, Coukos, Georges, Spertini, Francois, Thompson, John A, Obeid, Michel

“…Immune checkpoint inhibitors are reshaping the prognosis of many cancer and are progressively becoming the standard of care in the treatment of many tumour…”
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Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma by Mohsen, Mona O, Speiser, Daniel E, Michaux, Justine, Pak, HuiSong, Stevenson, Brian J, Vogel, Monique, Inchakalody, Varghese Philipose, de Brot, Simone, Dermime, Said, Coukos, Georges, Bassani-Sternberg, Michal, Bachmann, Martin F

“…BackgroundHarnessing the immune system to purposely recognize and destroy tumors represents a significant breakthrough in clinical oncology. Non-synonymous…”
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PD-1-expressing macrophages and CD8 T cells are independent predictors of clinical benefit from PD-1 inhibition in advanced mesothelioma by Homicsko, Krisztian, Zygoura, Panagiota, Norkin, Maxim, Tissot, Stephanie, Shakarishvili, Nicholas, Popat, Sanjay, Curioni-Fontecedro, Alessandra, O'Brien, Mary, Pope, Anthony, Shah, Riyaz, Fisher, Patricia, Spicer, James, Roy, Amy, Gilligan, David, Rusakiewicz, Sylvie, Fortis, Ekaterina, Marti, Nesa, Kammler, Roswitha, Finn, Stephen P, Coukos, Georges, Dafni, Urania, Peters, Solange, Stahel, Rolf A

“…BackgroundFew tissue biomarkers exist to date that could enrich patient with cancer populations to benefit from immune checkpoint blockade by programmed cell…”
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Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients by Rockinger, Georg Alexander, Guillaume, Philippe, Cachot, Amélie, Saillard, Margaux, Speiser, Daniel E, Coukos, Georges, Harari, Alexandre, Romero, Pedro J, Schmidt, Julien, Jandus, Camilla

“…BackgroundWith immunotherapy gaining increasing approval for treatment of different tumor types, scientists rely on cutting edge methods for the monitoring of…”
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Hot-to-Global Volume Ratio (HGVR): A novel tool to predict PD-L1 tumoral expression and outcome in NSCLC patients treated with checkpoint inhibitors using standard FDG PET/CT by Jreige, Mario, Letovanec, Igor, Peters, Solange, Cristina, Valerie, Coukos, Georges, Prior, John, Schaefer, Niklaus

“…Purpose: Humanized anti-PD-L1 or anti-PD-1 IgG1 monoclonal antibody can restore tumor-specific T-cell immunity by inhibiting the binding of PD-L1 to PD-1. It…”
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Abstract 985: The EurOPDX EDIReX project: Towards a European research infrastructure on patient-derived cancer models by Medico, Enzo, Bentires-Alj, Mohamed, Biankin, Andrew V., Bruna, Alejandra, Byrne, Annette T., Caldas, Carlos, Clarke, Robert B., Coukos, Georges, Elemento, Olivier, Hidalgo, Manuel, Inghirami, Giorgio, Jong, Steven de, Jonkers, Jos, Krenek, Ales, Leucci, Eleonora, Maelandsmo, Gunhild Mari, Mayrhofer, Michaela Th, Meehan, Terrence F., Niclou, Simone P., Pelicci, Pier Giuseppe, Piris-Gimenez, Alejandro, Price, Leo, Roman-Roman, Sergio, Trusolino, Livio, Vezzadini, Luca, Villanueva, Alberto, Vinolo, Emilie

“…Abstract Counteracting high attrition rates in anticancer drug development and providing optimal therapeutic management of cancer patients require preclinical…”
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Corticotropin-releasing factor and parturition: plasma and amniotic fluid levels and placental binding sites by Petraglia, F, Giardino, L, Coukos, G, Calza, L, Vale, W, Genazzani, A R

“…We evaluated levels of corticotropin-releasing factor in the plasma and amniotic fluid of women who had spontaneous vaginal delivery or elective cesarean…”
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Plasma and amniotic fluid immunoreactive neuropeptide-Y level changes during pregnancy, labor, and at parturition by Petraglia, F, Coukos, G, Battaglia, C, Bartolotti, A, Volpe, A, Nappi, C, Segre, A, Genazzani, A R

“…This study was designed to determine the presence of and possible changes in plasma and amniotic fluid immunoreactive neuropeptide-Y (irNPY) levels in pregnant…”
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Neuroendocrine mechanisms regulating placental hormone production by Petraglia, F, Angioni, S, Coukos, G, Uccelli, E, DiDomenica, P, De Ramundo, B M, Genazzani, A D, Garuti, G C, Segre, A

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