Search Results - "Coukell, Allan"

Antimicrobial drug use in food-producing animals and associated human health risks: what, and how strong, is the evidence? by Hoelzer, Karin, Wong, Nora, Thomas, Joe, Talkington, Kathy, Jungman, Elizabeth, Coukell, Allan

“…Antimicrobial resistance is a public health threat. Because antimicrobial consumption in food-producing animals contributes to the problem, policies…”
Get full text

Reforming the 340B Drug Pricing Program: Tradeoffs Between Hospital and Manufacturer Revenues by Coukell, Allan J, Dickson, Sean

Get more information

Revised Version of Research Letter by Nikpay et al and Associated Changes for Accompanying Commentary by Coukell, Allan J, Dickson, Sean

Get more information

Assessing the safety and effectiveness of devices after US Food and Drug Administration approval: FDA-mandated postapproval studies by Reynolds, Ian S, Rising, Joshua P, Coukell, Allan J, Paulson, Kirsten H, Redberg, Rita F

“…Postmarketing surveillance is critical to evaluating the safety and effectiveness of medical devices. The US Food and Drug Administration (FDA) may order the…”
Get more information

Long-term active surveillance of implantable medical devices: an analysis of factors determining whether current registries are adequate to expose safety and efficacy problems by Banerjee, Samprit, Campbell, Bruce, Rising, Josh, Coukell, Allan, Sedrakyan, Art

“…The balance between preapproval and postapproval data collection required by regulatory agencies (eg, FDA) is gradually shifting.6 Traditionally, long-term…”
Get full text

Risks of compounded drugs by Coukell, Allan

Get more information

Shared Platform for Antibiotic Research and Knowledge: A Collaborative Tool to SPARK Antibiotic Discovery by Thomas, Joe, Navre, Marc, Rubio, Aileen, Coukell, Allan

“…The discovery of urgently needed antibiotics is hindered by challenges to information sharing. To help address this challenge, The Pew Charitable Trusts…”
Get full text

Vinorelbine in advanced non-small cell lung cancer. A pharmacoeconomic review by Coukell, A J, Noble, S, Faulds, D

“…Vinorelbine is a semisynthetic vinca alkaloid that is effective against advanced non-small cell lung cancer (NSCLC). Myelosuppression is the primary…”
Get full text

Roadmap for antibiotic discovery by Shore, Carolyn K., Coukell, Allan

“…There are no antibiotic candidates simply waiting to be brought to market. Overcoming the scientific barriers to innovation will require research and…”
Get full text

Cyclosporin microemulsion (Neoral). A pharmacoeconomic review of its use compared with standard cyclosporin in renal and hepatic transplantation by Coukell, A J, Plosker, G L

“…Cyclosporin microemulsion (Neoral) is a self-emulsifying preconcentrate of cyclosporin which is more rapidly and consistently absorbed than the original…”
Get full text

Sumatriptan. A pharmacoeconomic review of its use in migraine by Coukell, A J, Lamb, H M

“…Migraine is a common illness characterised by severe, often throbbing and/or unilateral headache, which may be accompanied by sensitivity to light or noise. A…”
Get full text

On the Road to Discovering Urgently Needed Antibiotics: So Close Yet So Far Away by Kim, Wes, Prosen, Katherine R., Lepore, Cara J., Coukell, Allan

Get full text

Pravastatin. A pharmacoeconomic review of its use in primary and secondary prevention of coronary heart disease by Coukell, A J, Wilde, M I

“…Coronary heart disease (CHD) is a major cause of death and illness in industrialised countries. Like other hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase…”
Get full text

Understanding Payer Perspectives on Value in the Use of Pharmaceuticals in the United States by Brogan, Andrew P, Hogue, Susan L, Vekaria, Renu M, Reynolds, Ian, Coukell, Allan

“…In recent years, value assessment frameworks have been introduced to inform discussions about how to define and assess value in the U.S. health care system…”
Get full text

Clopidogrel by Coukell, A J, Markham, A

“…Clopidogrel is a thienopyridine that irreversibly inhibits platelet aggregation by selectively binding to adenylate cyclase-coupled ADP receptors on the…”
Get full text

Mexiletine : A review of its therapeutic use in painful diabetic neuropathy by JARVIS, B, COUKELL, A. J

“…Mexiletine is an orally active local anaesthetic agent which is structurally related to lidocaine (lignocaine) and has been used for alleviating neuropathic…”
Get full text

Polyethylene glycol-liposomal doxorubicin : A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of AIDS-related Kaposi's sarcoma by COUKELL, A. J, SPENCER, C. M

“…Doxorubicin is an antineoplastic drug which has in vitro and in vivo activity against a number of malignancies including Kaposi's sarcoma. Incorporation of…”
Get full text

Liposomal amphotericin B : Therapeutic use in the management of fungal infections and visceral leishmaniasis by COUKELL, A. J, BROGDEN, R. N

“…Incorporation of amphotericin B into small unilamellar liposomes (AmBisome) alters the pharmacokinetic properties of the drug, but allows it to retain…”
Get full text

Epirubicin : An updated review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of breast cancer by COUKELL, A. J, FAULDS, D

“…Epirubicin, an anthracycline antitumour antibiotic which is structurally related to doxorubicin, is among the most active single agents used in the management…”
Get full text

Amisulpride: A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Efficacy in the Management of Schizophrenia by Coukell, Allan J., Spencer, Caroline M., Benfield, Paul

Get full text