Search Results - "Couillault, Coline A"

A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies by Hegde, Aparna, Jayaprakash, Priyamvada, Couillault, Coline A, Piha-Paul, Sarina, Karp, Daniel, Rodon, Jordi, Pant, Shubham, Fu, Siqing, Dumbrava, Ecaterina E, Yap, Timothy A, Subbiah, Vivek, Bhosale, Priya, Coarfa, Cristian, Higgins, Jack P, Williams, Eric T, Wilson, Thomas F, Lim, JoAnn, Meric-Bernstam, Funda, Sumner, Elizabeth, Zain, Hira, Nguyen, Di, Nguyen, Ly M, Rajapakshe, Kimal, Curran, Michael A, Hong, David S

“…As hypoxia can mediate resistance to immunotherapy, we investigated the safety, tolerability, and efficacy of combining evofosfamide, a prodrug that alleviates…”
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Lefitolimod (TLR agonist) and ipilimumab in patients with advanced solid tumors: A phase I trial by Nardo, Mirella, Reilley, Matthew, Biter, Amadeo, Lim, JoAnn, Bean, Stacie A., Nguyen, Ly Minh, Bhosale, Priya, Ager, Casey, Couillault, Coline A, Piha-Paul, Sarina A., Fu, Siqing, Tsimberidou, Apostolia Maria, Yap, Timothy A., Naing, Aung, Rodon Ahnert, Jordi, Subbiah, Vivek, Karp, Daniel D., Curran, Michael A., Hong, David S.

“…2564 Background: The TLR-9 agonist lefitolimod (MGN1703) significantly increases the Th1 response in pre-clinical models and has demonstrated antitumor…”
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