Search Results - "Coudreuse, Damien Y M"
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Wnt Gradient Formation Requires Retromer Function in Wnt-Producing Cells
Published in Science (American Association for the Advancement of Science) (12-05-2006)“…Wnt proteins function as morphogens that can form long-range concentration gradients to pattern developing tissues. Here, we show that the retromer, a…”
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Mammalian Wnt3a is Released on Lipoprotein Particles
Published in Traffic (Copenhagen, Denmark) (01-03-2009)“…Little is known about the release and intercellular transport of Wnt proteins from mammalian cells. Lipoproteins may act as carriers for the intercellular…”
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Wnt Signaling Requires Retromer-Dependent Recycling of MIG-14/Wntless in Wnt-Producing Cells
Published in Developmental cell (01-01-2008)“…Wnt proteins are secreted signaling molecules that play a central role in development and adult tissue homeostasis. We have previously shown that Wnt signaling…”
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The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans
Published in Genes & development (15-05-2002)“…Axin, APC, and the kinase GSK3 beta are part of a destruction complex that regulates the stability of the Wnt pathway effector beta-catenin. In C. elegans,…”
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Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans
Published in Developmental biology (15-08-2007)“…Axin is a central component of the canonical Wnt signaling pathway that interacts with the adenomatous polyposis coli protein APC and the kinase GSK3β to…”
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