Search Results - "Couchman, L."

A review of analytical parameters in ‘rapid’ liquid chromatographic methods for bioanalysis: Can we do better? by Lawlor, K, Clausen, J, Johnston, A, Edge, A, Wolff, K, Castrignanò, E, Couchman, L

“…•For many applications there are benefits to be gained in reducing analysis times.•The use of short LC columns (<50 mm) and high flow rates (exceeding 1…”
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Post mortem blood bromazolam concentrations and co-findings in 96 coronial cases within England and Wales by Hikin, L J, Coombes, G, Rice-Davies, K, Couchman, L, Smith, P R, Morley, S R

“…Bromazolam is a newly emerging benzodiazepine drug which is not licensed for medicinal use. It may be sourced as a New Psychoactive Substance (NPS) for its…”
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Commercial insulin immunoassays fail to detect commonly prescribed insulin analogues by Parfitt, C., Church, D., Armston, A., Couchman, L., Evans, C., Wark, G., McDonald, T.J.

“…Blood insulin and C-peptide are key investigations in the differential diagnosis of hypoglycaemia. Analogues of insulin have modified primary-sequences…”
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An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography–tandem mass spectrometry by Couchman, L., Birch, M., Ireland, R., Corrigan, A., Wickramasinghe, S., Josephs, D., Spicer, J., Flanagan, R. J.

“…Tyrosine kinase inhibitors (TKIs) are used to treat a number of cancers, including chronic myeloid leukaemia and hepatocellular carcinoma. Therapeutic drug…”
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Plasma and Urine Levamisole in Clinical Samples Containing Benzoylecgonine: Absence of Aminorex by Handley, S A, Belsey, S L, Couchman, L, Flanagan, R J

“…Aminorex has been reported as a metabolite of levamisole in man, but data on the aminorex concentrations in clinical samples are scant. We thus measured…”
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An automated method for the simultaneous measurement of azole antifungal drugs in human plasma or serum using turbulent flow liquid chromatography-tandem mass spectrometry by Couchman, L., Buckner, S. L., Morgan, P. E., Ceesay, M. M., Pagliuca, A., Flanagan, R. J.

“…Azole antifungal drugs are important in the prophylaxis and treatment of invasive aspergillosis. Therapeutic drug monitoring may be indicated to (1) monitor…”
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The use of turbulent flow chromatography for rapid, on-line analysis of tryptic digests by Couchman, L., Jones, D. J. L., Moniz, C. F.

“…Rationale Following digestion of proteins with trypsin, digests are typically subjected to further 'clean‐up' prior to liquid chromatography/mass spectometry…”
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LC-MS/MS for the analysis of 25-hydroxyvitamin D: Much more than a single technique by Couchman, L, Carter, G.D, Jones, J.C, Moniz, C

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Basic drug analysis by strong cation-exchange liquid chromatography-tandem mass spectrometry: simultaneous analysis of amisulpride, and of metamfetamine and amfetamine in serum/plasma by Couchman, L., Morgan, P. E., Flanagan, R. J.

“…In the HPLC of basic drugs and metabolites, good efficiency and peak shape can often be attained using strong cation‐exchange packings with isocratic 100%…”
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False-Positive Buprenorphine by CEDIA in Patients Prescribed Amisulpride or Sulpiride by Birch, M.A., Couchman, L., Pietromartire, S., Karna, T., Paton, C., McAllister, R., Marsh, A., Flanagan, R.J.

“…Buprenorphine is a potent partial opioid agonist that is analyzed in urine to (i) monitor adherence to maintenance or detoxification therapy and (ii) detect…”
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Clinical relevance of serum total 25-hydroxyvitamin D as measured by immunoassay and turboflow LC-MS/MS by Couchman, L, Musto, R, Vincent, R, Clarke, R, Langworthy, R, Robinson, S, Moniz, C

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A coupled finite volume and material point method for two-phase simulation of liquid–sediment and gas–sediment flows by Baumgarten, Aaron S., Couchman, Benjamin L.S., Kamrin, Ken

“…Mixtures of fluids and granular sediments play an important role in many industrial, geotechnical, and aerospace engineering problems, from waste management…”
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Hidden Markov models for multiaspect target classification by Runkle, P.R., Bharadwaj, P.K., Couchman, L., Carin, L.

“…This article presents a new approach for target identification, in which we fuse scattering data from multiple target-sensor orientations. The multiaspect data…”
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Genetic algorithm wavelet design for signal classification by Jones, E., Runkle, P., Dasgupta, N., Couchman, L., Carin, L.

“…Biorthogonal wavelets are applied to parse multiaspect transient scattering data in the context of signal classification. A language-based genetic algorithm is…”
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Multiaspect target identification with wave-based matched pursuits and continuous hidden Markov models by Runkle, P., Carin, L., Couchman, L., Yoder, T.J., Bucaro, J.A.

“…Multiaspect target identification is effected by fusing the features extracted from multiple scattered waveforms; these waveforms are characteristic of viewing…”
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Class-based target identification with multiaspect scattering data by Dasgupta, N., Runkle, P., Carin, L., Couchman, L., Yoder, T., Bucaro, J., Dobeck, G.J.

“…In underwater sensing applications, it is often difficult to train a classifier in advance for all targets that may be seen during testing, due to the large…”
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Born series in obstacle scattering by Ghosh Roy, D.N., Orris, G., Couchman, L.S.

“…A Born series is derived for obstacle scattering without using integral equations. It is demonstrated that the Born approximation satisfies reciprocity…”
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The smell of death: an unusual case of poisoning with the organophosphorus pesticide chlorfenvinphos by Couchman, L, Slaughter, JA, Coombes, G, Johnston, A, Ogoti, E, Holt, DW

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The use of turbulent flow chromatography for rapid, on-line analysis of tryptic digests: Turbulent flow chromatography for analysis of tryptic digests by Couchman, L., Jones, D. J. L., Moniz, C. F.

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Inversion of penetrable obstacles from far-field data on narrow angular apertures by Warner, JA, Roy, DN, Bucaro, J, Couchman, L

“…Reported in this paper are reconstructions of shape and material parameters of two-dimensional, homogeneous, acoustic, penetrable obstacles of arbitrary…”
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