Search Results - "Couarraze, Guy"

Use of co-grinding as a solvent-free solid state method to synthesize dibenzophenazines by Carlier, Leslie, Baron, Michel, Chamayou, Alain, Couarraze, Guy

“…Many synthetic methods exist for dibenzoquinoxalines but only a few for dibenzophenazines and their aza derivatives and even less are ‘green’. Some…”
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Percutaneous absorption of sunscreens from liquid crystalline phases by Brinon, Laure, Geiger, Sandrine, Alard, Valérie, Doucet, Jean, Tranchant, Jean-François, Couarraze, Guy

“…The purpose of the present study was to investigate the effects of two nonionic surfactants with liquid crystalline structures on the cutaneous availability of…”
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Greener pharmacy using solvent-free synthesis: Investigation of the mechanism in the case of dibenzophenazine by Carlier, Leslie, Baron, Michel, Chamayou, Alain, Couarraze, Guy

“…The mechanism of the solvent-free solid-state dibenzophenazine synthesis by dry co-grinding in a vibratory ball-mill has been investigated. The kinetics of the…”
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Quantitative measurements of localized density variations in cylindrical tablets using X-ray microtomography by Busignies, Virginie, Leclerc, Bernard, Porion, Patrice, Evesque, Pierre, Couarraze, Guy, Tchoreloff, Pierre

“…Direct compaction is a complex process that results in a density distribution inside the tablets which is often heterogeneous. Therefore, the density…”
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Extruder scale-up assessment in the process of extrusion-spheronization: comparison of radial and axial systems by a design of experiments approach by Désiré, Amélie, Paillard, Bruno, Bougaret, Joël, Baron, Michel, Couarraze, Guy

“…Scaling-up the extrusion-spheronization process involves the separate scale-up of each of the five process steps: dry mixing, granulation, extrusion,…”
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Cross-linking of chitosan and chitosan/poly(ethylene oxide) beads: A theoretical treatment by Martinez, Leticia, Agnely, Florence, Leclerc, Bernard, Siepmann, Juergen, Cotte, Marine, Geiger, Sandrine, Couarraze, Guy

“…The major aim of this study was to get deeper insight into the process of polymer cross-linking and the resulting structure of beads based on chitosan (CS) or…”
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Compaction behaviour and new predictive approach to the compressibility of binary mixtures of pharmaceutical excipients by Busignies, V., Leclerc, B., Porion, P., Evesque, P., Couarraze, G., Tchoreloff, P.

“…The compressibility of three pharmaceutical excipients (microcrystalline cellulose, lactose and anhydrous calcium phosphate) and their binary mixtures was…”
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Release of mifepristone from biodegradable matrices: experimental and theoretical evaluations by Charlier, Anne, Leclerc, Bernard, Couarraze, Guy

“…Diffusion of mifepristone in poly [( d, l) lactide-co-glycolide)] films was studied by release experiments. Five 50/50 copolymers of increasing molecular…”
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Application of percolation model to the tensile strength and the reduced modulus of elasticity of three compacted pharmaceutical excipients by Busignies, Virginie, Leclerc, Bernard, Porion, Patrice, Evesque, Pierre, Couarraze, Guy, Tchoreloff, Pierre

“…Percolation theory has been applied to several mechanical properties of pharmaceutical tablets. This power law describes the change of tablet’s properties with…”
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Investigation and modelling approach of the mechanical properties of compacts made with binary mixtures of pharmaceutical excipients by Busignies, V., Leclerc, B., Porion, P., Evesque, P., Couarraze, G., Tchoreloff, P.

“…Three pharmaceutical excipients (microcrystalline cellulose, lactose, anhydrous calcium phosphate) and their binary mixtures were compacted to form compacts of…”
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Liposomes dispersed within a thermosensitive gel : A new dosage form for ocular delivery of oligonucleotides by BOCHOT, A, FATTAL, E, GULIK, A, COUARRAZE, G, COUVREUR, P

“…The main goal of this study was to develop an ocular controlled release formulation of a model oligonucleotide (pdT16), contained within liposomes dispersed…”
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Compaction of crystallographic forms of pharmaceutical granular lactoses. II. Compacts mechanical properties by Busignies, Virginie, Tchoreloff, Pierre, Leclerc, Bernard, Hersen, Christine, Keller, Gérard, Couarraze, Guy

“…It is well known that the choice of the crystal form affects the physicochemical properties such as compaction behaviour. In this work, the mechanical…”
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The Effects of Relative Humidity and Super-Disintegrant Concentrations on the Mechanical Properties of Pharmaceutical Compacts by Hersen-Delesalle, Christine, Leclerc, Bernard, Couarraze, Guy, Busignies, Virginie, Tchoreloff, Pierre

“…The influence of the composition and the relative humidity on the properties of pharmaceutical compacts prepared from mixtures of three excipients and three…”
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Structural parameters involved in the permeation of propranolol HCl by iontophoresis and enhancers by Chesnoy, Sophie, Durand, Dominique, Doucet, Jean, Couarraze, Guy

“…The purpose of this work was to study the effect of iontophoretic transport of Propranolol hydrochloride on the lipidic organization of the stratum corneum…”
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Wetting behavior of bile salt-lipid dispersions and dissolution media patterned after intestinal fluids by Luner, P E, Vander Kamp, D

“…The wetting properties of bile salt-lipid solutions and dispersions patterned after the contents of the upper intestine in the fed and fasted states were…”
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Complex dispersions of multilamellar vesicles: a promising new carrier for controlled release and protection of encapsulated molecules by Genty, Muriel, Couarraze, Guy, Laversanne, René, Degert, Corinne, Maccario, Jean, Grossiord, Jean-Louis

“…Multilamellar vesicles called Spherulites ® have recently been discovered and are being developed for encapsulation applications. In this study, we present new…”
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Powder dynamic contact angle measurements: Young contact angles and effectively wet perimeters by Pepin, Xavier, Blanchon, Sylvène, Couarraze, Guy

“…Dynamic contact angle (DCA) measurements on powder are of great interest for the prediction of various processes. Powder covered slides exhibit rough surfaces…”
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Nasal absorption of tyrosine-linked model compounds by Yang, C, Mitra, A K

“…The objective of this research is to explore the amino acid carrier-mediated pathway for nasal uptake of tyrosine-linked model compounds. These molecules were…”
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Investigation of PDMS gels and solutions by small angle scattering by Geissler, Eric, Horkay, Ferenc, Hecht, Anne-Marie, Rochas, Cyrille, Lindner, Peter, Bourgaux, Claudie, Couarraze, Guy

“…Measurements of swollen end-linked PDMS gels by means of small angle X-ray and neutron scattering are reported. Hexane and octane were used as solvents. The…”
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Power consumption profiles in high-shear wet granulation. I: Liquid distribution in relation to powder and binder properties by Pepin, X, Blanchon, S, Couarraze, G

“…Wet granulation processes frequently rely on the device power consumption profile to monitor the process endpoint. This work shows how the observed power…”
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