Search Results - "Cotton, Mark F"

Early Antiretroviral Therapy and Mortality among HIV-Infected Infants by Violari, Avy, Cotton, Mark F, Gibb, Diana M, Babiker, Abdel G, Steyn, Jan, Madhi, Shabir A, Jean-Philippe, Patrick, McIntyre, James A

“…The timing of initiation of antiretroviral therapy in HIV-infected infants has been debated, in part because of the potential long-term toxicity of the…”
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The Recombinant Bacille Calmette-Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing by Nieuwenhuizen, Natalie E, Kulkarni, Prasad S, Shaligram, Umesh, Cotton, Mark F, Rentsch, Cyrill A, Eisele, Bernd, Grode, Leander, Kaufmann, Stefan H E

“…The only licensed vaccine against tuberculosis (TB), bacille Calmette-Guérin (BCG), protects against severe extrapulmonary forms of TB but is virtually…”
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Pattern of Infectious Morbidity in HIV-Exposed Uninfected Infants and Children by Slogrove, Amy L, Goetghebuer, Tessa, Cotton, Mark F, Singer, Joel, Bettinger, Julie A

“…Almost 30% of children in Southern Africa are HIV exposed but uninfected (HEU) and experience exposures that could increase vulnerability to infectious…”
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Personal reflections on a new role in infectious diseases by Cotton, Mark F

“…Abstract only…”
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Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa by Loxton, André G, Knaul, Julia K, Grode, Leander, Gutschmidt, Andrea, Meller, Christiane, Eisele, Bernd, Johnstone, Hilary, van der Spuy, Gian, Maertzdorf, Jeroen, Kaufmann, Stefan H E, Hesseling, Anneke C, Walzl, Gerhard, Cotton, Mark F

“…Tuberculosis is a global threat to which infants are especially vulnerable. Effective vaccines are required to protect infants from this devastating disease…”
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Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial by Cotton, Mark F, Prof, Violari, Avy, FCPaed [SA], Otwombe, Kennedy, MSc, Panchia, Ravindre, MB, Dobbels, Els, FCPaed [SA], Rabie, Helena, FCPaed [SA], Josipovic, Deirdre, MB, Liberty, Afaaf, MB, Lazarus, Erica, MB, Innes, Steve, MB, van Rensburg, Anita Janse, Dip Nurs, Pelser, Wilma, RN, Truter, Handre, NDip, Madhi, Shabir A, Prof, Handelsman, Edward, MD, Jean-Philippe, Patrick, MD, McIntyre, James A, Prof, Gibb, Diana M, Prof, Babiker, Abdel G, Prof

“…Summary Background Interim results from the children with HIV early antiretroviral (CHER) trial showed that early antiretroviral therapy (ART) was life-saving…”
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A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation by Violari, Avy, Cotton, Mark F., Kuhn, Louise, Schramm, Diana B., Paximadis, Maria, Loubser, Shayne, Shalekoff, Sharon, Da Costa Dias, Bianca, Otwombe, Kennedy, Liberty, Afaaf, McIntyre, James, Babiker, Abdel, Gibb, Diana, Tiemessen, Caroline T.

“…Understanding HIV remission in rare individuals who initiated antiretroviral therapy (ART) soon after infection and then discontinued, may inform HIV cure…”
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Similar cortical morphometry trajectories from 5 to 9 years in children with perinatal HIV who started treatment before age 2 years and uninfected controls by Nwosu, Emmanuel C, Holmes, Martha J, Cotton, Mark F, Dobbels, Els, Little, Francesca, Laughton, Barbara, van der Kouwe, Andre, Robertson, Frances, Meintjes, Ernesta M

“…Life-long early ART (started before age 2 years), often with periods of treatment interruption, is now the standard of care in pediatric HIV infection…”
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Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis by Galileya, Lufina Tsirizani, Wasmann, Roeland E, Chabala, Chishala, Rabie, Helena, Lee, Janice, Njahira Mukui, Irene, Hesseling, Anneke, Zar, Heather, Aarnoutse, Rob, Turkova, Anna, Gibb, Diana, Cotton, Mark F, McIlleron, Helen, Denti, Paolo

“…The current World Health Organization (WHO) pediatric tuberculosis dosing guidelines lead to suboptimal drug exposures. Identifying factors altering the…”
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Multivariate approach for longitudinal analysis of brain metabolite levels from ages 5-11 years in children with perinatal HIV infection by van Biljon, Noëlle, Robertson, Frances, Holmes, Martha, Cotton, Mark F, Laughton, Barbara, van der Kouwe, Andre, Meintjes, Ernesta, Little, Francesca

“…•Analysis of longitudinal trajectories of brain metabolite levels offer increased power to detect group differences and confirmed elevated GPC+PCh levels in…”
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An analysis of the HIV testing cascade of a group of HIV-exposed infants from birth to 18 months in peri-urban Khayelitsha, South Africa by Nelson, Aurelie Kennedy, Cassidy, Tali, Trivino Duran, Laura, Cox, Vivian, Wedderburn, Catherine J, Giddy, Janet, Pieters, Pauline, Cotton, Mark F, Mutseyekwa, Tabitha, Rorwana, Bulelwa, Sibanda, Beryl, Bernheimer, Jonathan, Matise, Nopinky, Isaakidis, Petros, Maritz, Jean

“…Despite the reduction of HIV mother-to-child transmission, there are concerns regarding transmission rate in the breastfeeding period. We describe the routine…”
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Liver transient elastography values in healthy South African children by Rose, Penelope C, Cotton, Mark F, Otwombe, Kennedy, Innes, Steve, Nel, Etienne D

“…Transient elastography (TE) is a rapid noninvasive ultrasound-based technology that measures liver stiffness as a surrogate for liver fibrosis and controlled…”
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Mobile phone text messaging plus motivational interviewing versus usual care: study protocol for a randomized controlled trial to evaluate effects on breastfeeding, child health, and survival outcomes, among women living with HIV (MTI-MI) by Zunza, Moleen, Thabane, Lehana, Kuhn, Louise, Els, Christine, Cotton, Mark F, Young, Taryn

“…Abstract Background Many infants in low-resourced settings at high risk of infectious disease morbidity and death are deprived of the immunological and…”
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Correction to: Similar cortical morphometry trajectories from 5 to 9 years in children with perinatal HIV who started treatment before age 2 years and uninfected controls by Nwosu, Emmanuel C, Holmes, Martha J, Cotton, Mark F, Dobbels, Els, Little, Francesca, Laughton, Barbara, van der Kouwe, Andre, Robertson, Frances, Meintjes, Ernesta M

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Early inflammation as a footprint of increased mortality risk in infants living with HIV from three African countries by Morrocchi, Elena, Pascucci, Giuseppe R., Cotugno, Nicola, Pighi, Chiara, Dominguez-Rodriguez, Sara, Petrara, Maria Raffaella, Tagarro, Alfredo, Kuhn, Louise, Cotton, Mark F., Otwombe, Kennedy, Lain, Maria G., Vaz, Paula, Barnabas, Shaun L., Spyer, Moira J., Lopez, Elisa, Fernández-Luis, Sheila, Nhampossa, Tacilta, Maiga, Almoustapha I., Dolo, Oumar, De Rossi, Anita, Rojo, Pablo, Giaquinto, Carlo, Lichterfeld, Mathias, Violari, Avy, Smit, Theresa, Behuhuma, Osee, Klein, Nigel, De Armas, Lesley, Pahwa, Savita, Rossi, Paolo, Palma, Paolo

“…In this work our aim was to identify early biomarkers in plasma samples associated with mortality in children with perinatal HIV treated early in life, to…”
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Maternal ART throughout gestation prevents caudate volume reductions in neonates who are HIV exposed but uninfected by Ibrahim, Abdulmumin, Warton, Fleur L, Fry, Samantha, Cotton, Mark F, Jacobson, Sandra W, Jacobson, Joseph L, Molteno, Christopher D, Little, Francesca, van der Kouwe, Andre J W, Laughton, Barbara, Meintjes, Ernesta M, Holmes, Martha J

“…Successful programmes for prevention of vertical HIV transmission have reduced the risk of infant HIV infection in South Africa from 8% in 2008 to below 1% in…”
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HIV-1 Persistence in Children during Suppressive ART by Katusiime, Mary Grace, Van Zyl, Gert U, Cotton, Mark F, Kearney, Mary F

“…There is a growing number of perinatally HIV-1-infected children worldwide who must maintain life-long ART. In early life, HIV-1 infection is established in an…”
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Reactivity of routine HIV antibody tests in children who initiated antiretroviral therapy in early infancy as part of the Children with HIV Early Antiretroviral Therapy (CHER) trial: a retrospective analysis by Payne, Helen, Dr, Mkhize, Nonhlanhla, PhD, Otwombe, Kennedy, MSc, Lewis, Joanna, PhD, Panchia, Ravindre, MBBCh, Callard, Robin, PhD, Morris, Lynn, DPhil, Babiker, Abdel, PhD, Violari, Avy, FCPaed [SA], Cotton, Mark F, PhD, Klein, Nigel J, PhD, Gibb, Diana M, MD

“…Summary Background Early antiretroviral therapy (ART) and virological suppression can affect evolving antibody responses to HIV infection. We aimed to assess…”
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The largest HIV-1-infected T cell clones in children on long-term combination antiretroviral therapy contain solo LTRs by Botha, Johannes C, Demirov, Dimiter, Gordijn, Carli, Katusiime, Mary Grace, Bale, Michael J, Wu, Xiaolin, Wells, Daria, Hughes, Stephen H, Cotton, Mark F, Mellors, John W, Kearney, Mary F, van Zyl, Gert U

“…Combination antiretroviral therapy (cART) suppresses viral replication but does not cure HIV infection because a reservoir of infectious (intact) HIV…”
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Longitudinal increases of brain metabolite levels in 5-10 year old children by Holmes, Martha J, Robertson, Frances C, Little, Francesca, Randall, Steven R, Cotton, Mark F, van der Kouwe, Andre J W, Laughton, Barbara, Meintjes, Ernesta M

“…Longitudinal magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) studies reveal significant changes in brain structure and structural networks…”
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