Search Results - "Cottle, Taylor"

Achieving single nucleotide sensitivity in direct hybridization genome imaging by Wang, Yanbo, Cottle, W. Taylor, Wang, Haobo, Gavrilov, Momcilo, Zou, Roger S., Pham, Minh-Tam, Yegnasubramanian, Srinivasan, Bailey, Scott, Ha, Taekjip

“…Direct visualization of point mutations in situ can be informative for studying genetic diseases and nuclear biology. We describe a direct hybridization genome…”
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Monocyte distribution width as a pragmatic screen for SARS-CoV-2 or influenza infection by Badaki-Makun, Oluwakemi, Levin, Scott, Debraine, Arnaud, Hernried, Benjamin, Malinovska, Alexandra, Smith, Aria, Toerper, Matthew, Fenstermacher, Katherine Z. J., Cottle, Taylor, Latallo, Malgorzata, Rothman, Richard E., Hinson, Jeremiah S.

“…Monocyte distribution width (MDW) is a novel marker of monocyte activation, which is known to occur in the immune response to viral pathogens. Our objective…”
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Mapping cellular responses to DNA double-strand breaks using CRISPR technologies by Liu, Yang, Cottle, W. Taylor, Ha, Taekjip

“…DNA double-strand breaks (DSBs) are genotoxic lesions that induce extensive chromatin modifications and 3D genome reorganization.Comprehensive interrogation of…”
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Calcineurin homologous protein isoform 2 supports tumor survival via the sodium hydrogen exchanger isoform 1 in non-small cell lung cancer by Cottle, Wayne Taylor, Wallert, Clarice Hayley, Anderson, Kristine Kay, Tran, Michelle Fang, Bakker, Clare Loraine, Wallert, Mark Anthony, Provost, Joseph John

“…Maintaining intracellular pH is crucial for preserving healthy cellular behavior and, when dysregulated, results in increased proliferation, migration, and…”
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Real-Time Measurement of Molecular Tension during Cell Adhesion and Migration Using Multiplexed Differential Analysis of Tension Gauge Tethers by Jo, Myung Hyun, Cottle, W. Taylor, Ha, Taekjip

“…Cells must respond specifically and dynamically to mechanical cues from the extracellular environment and dysregulation of extracellular force sensing leads to…”
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Phosphorylation and Palmitoylation Dynamically Regulate Sodium Hydrogen Exchanger Isoform 1 (NHE1) Activity: Implications in Health and Disease by Hovde, Moriah J., Bolland, Danielle E., Bakker, Clair, Cottle, Taylor, Wallert, Mark A., Vaughan, Roxanne A., Provost, Joseph J., Foster, James D.

“…The SLC9 family is made up of nine isoforms of sodium hydrogen exchangers (NHE) which regulate pH by exchanging an intracellular proton for an extracellular…”
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Mapping Cellular Responses to DNA Double-strand Break Using CRISPR Technologies by Liu, Yang, Cottle, W. Taylor, Ha, Taekjip

“…DNA double-strand breaks (DSBs) are one of the most genotoxic DNA lesions, driving a range of pathological defects from cancers to immunodeficiencies. To…”
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Genome oligopaint via local denaturation fluorescence in situ hybridization by Wang, Yanbo, Cottle, Wayne Taylor, Wang, Haobo, Feng, Xinyu Ashlee, Mallon, John, Gavrilov, Momcilo, Bailey, Scott, Ha, Taekjip

“…Cas9 in complex with a programmable guide RNA targets specific double-stranded DNA for cleavage. By harnessing Cas9 as a programmable loader of superhelicase…”
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Calcineurin Homologous Protein Expression Regulates Na + /H + Exchanger 1 Dependent Tumor Survival by Cottle, Wayne Taylor, Wallert, Mark Anthony, Provost, Joseph John

“…Abstract only Calcineurin Homologous Proteins 2 (CHP2) is a cofactor which regulates the Sodium Hydrogen Exchanger Isoform 1 (NHE1), a transmembrane proton…”
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Sodium Hydrogen Exchanger 1 and Calcineurin Homologous Protein: A Critical for Survival Mechanism in Non‐Small Cell Lung Cancer by Cottle, Wayne Taylor, Wallert, Mark, Provost, Joseph John

“…Abstract only Calcineurin Homologous Protein 1 and 2 (CHP1 and CHP2) are competing cofactors which regulate the exchange activity of the Sodium Hydrogen…”
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