Search Results - "Cottin, Patrick"

Down-regulation of MyoD by Calpain 3 Promotes Generation of Reserve Cells in C2C12 Myoblasts by Stuelsatz, Pascal, Pouzoulet, Frédéric, Lamarre, Yann, Dargelos, Elise, Poussard, Sylvie, Leibovitch, Serge, Cottin, Patrick, Veschambre, Philippe

“…Calpain 3 is a calcium-dependent cysteine protease that is primarily expressed in skeletal muscle and is implicated in limb girdle muscular dystrophy type 2A…”
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Myoblast migration is regulated by calpain through its involvement in cell attachment and cytoskeletal organization by Dedieu, Stéphane, Poussard, Sylvie, Mazères, Germain, Grise, Florence, Dargelos, Elise, Cottin, Patrick, Brustis, Jean-Jacques

“…Cell migration is a fundamental cellular function particularly during skeletal muscle development. Ubiquitous calpains are well known to play a pivotal role…”
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Comparative proteomic analysis of myotube caveolae after milli-calpain deregulation by Goudenege, Sébastien, Dargelos, Elise, Claverol, Stéphane, Bonneu, Marc, Cottin, Patrick, Poussard, Sylvie

“…Caveolae are specialised RAFTs (detergent-resistant membrane microdomains enriched in cholesterol and glycosphingolipids). Caveolin, the main caveolae protein,…”
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Coordinate activation of lysosomal, Ca2+-activated and ATP-ubiquitin-dependent proteinases in the unweighted rat soleus muscle by TAILLANDIER, Daniel, AUROUSSEAU, Eveline, MEYNIAL-DENIS, Dominique, BECHET, Daniel, FERRARA, Marc, COTTIN, Patrick, DUCASTAING, André, BIGARD, Xavier, GUEZENNEC, Charles-Yannick, SCHMID, Hans-Peter, ATTAIX, Didier

“…Nine days of hindlimb suspension resulted in atrophy (55%) and loss of protein (53%) in rat soleus muscle due to a marked elevation in protein breakdown (66%,…”
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Involvement of micro-calpain (CAPN 1) in muscle cell differentiation by Moyen, Catherine, Goudenege, Sébastien, Poussard, Sylvie, Sassi, Abdessattar Hadj, Brustis, Jean-Jacques, Cottin, Patrick

“…Several studies have already demonstrated that micro- and milli-calpains (CAPN 1–CAPN 2), calcium-dependent intracellular cysteine-proteases are involved in…”
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What is a “Maison des Adolescents”? A history of integrated youth health care services in France by Benoit, Laelia, Cottin, Patrick, Moro, Marie R.

“…Aim Since 1999, the development of more than 100 “Maisons des Adolescents” (MDAs) has enabled young persons to gain access to specific care in integrated…”
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MAP Kinase-dependent Degradation of p27Kip1 by Calpains in Choroidal Melanoma Cells by Delmas, Christelle, Aragou, Nathalie, Poussard, Sylvie, Cottin, Patrick, Darbon, Jean-Marie, Manenti, Stéphane

“…We investigated the status and the regulation of the cyclin-dependent kinases (CDK) inhibitor p27 Kip1 in a choroidal melanoma tumor-derived cell line (OCM-1)…”
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Calpain and myogenesis: development of a convenient cell culture model by Dedieu, Stéphane, Dourdin, Nathalie, Dargelos, Elise, Poussard, Sylvie, Veschambre, Philippe, Cottin, Patrick, Brustis, Jean-Jacques

“…Previous studies have led us to hypothesize that m-calpain plays a pivotal role in myoblast fusion through its involvement in cell membrane and cytoskeleton…”
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Up-regulation of calcium-dependent proteolysis in human myoblasts under acute oxidative stress by Dargelos, Elise, Brulé, Cédric, Stuelsatz, Pascal, Mouly, Vincent, Veschambre, Philippe, Cottin, Patrick, Poussard, Sylvie

“…The reduced regenerative potential of muscle fibres, most likely due to a decreased number and/or function of satellite cells, could play a significant role in…”
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Calcium-dependent proteolytic system and muscle dysfunctions: A possible role of calpains in sarcopenia by Dargelos, E., Poussard, S., Brulé, C., Daury, L., Cottin, P.

“…The calcium-dependent proteolytic system is composed of cysteine proteases named calpains. They are ubiquitous or tissue-specific enzymes. The two best…”
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Calpains: Markers of tumor aggressiveness? by Roumes, Hélène, Leloup, Ludovic, Dargelos, Elise, Brustis, Jean-Jacques, Daury, Laetitia, Cottin, Patrick

“…Rhabdomyosarcoma (RMS) are soft-tissue sarcoma commonly encountered in childhood. RMS cells can acquire invasive behavior and form metastases. The metastatic…”
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Involvement of the ERK/MAP kinase signalling pathway in milli-calpain activation and myogenic cell migration by Leloup, Ludovic, Daury, Laetitia, Mazères, Germain, Cottin, Patrick, Brustis, Jean-Jacques

“…Recent research carried out in our laboratory has shown that IGF-1, TGF-β1, and insulin were able to strongly stimulate myoblast migration by increasing…”
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Proteomic study of calpain interacting proteins during skeletal muscle aging by Brulé, C., Dargelos, E., Diallo, R., Listrat, A., Béchet, D., Cottin, P., Poussard, S.

“…Aging is associated with a progressive and involuntary loss of muscle mass also known as sarcopenia. This condition represents a major public health concern…”
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Calpains: Markers of tumor aggressiveness? by Roumes, Hélène, Leloup, Ludovic, Dargelos, Elise, Brustis, Jean-Jacques, Daury, Laetitia, Cottin, Patrick

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Involvement of the calcium-dependent proteolytic system in skeletal muscle aging by Dargelos, Elise, Brulé, Cédric, Combaret, Lydie, Hadj-Sassi, Abdessatar, Dulong, Sandrine, Poussard, Sylvie, Cottin, Patrick

“…Aging is associated with a progressive and involuntary loss of muscle mass also known as sarcopenia. This condition represents a major public health concern…”
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Involvement of calpains in growth factor-mediated migration by Leloup, Ludovic, Mazères, Germain, Daury, Laetitia, Cottin, Patrick, Brustis, Jean-Jacques

“…Previous research in our laboratory has already shown the importance of the role played by ubiquitous calpains during myoblast migration. The aim of this study…”
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Involvement of myogenic regulator factors during fusion in the cell line C2C12 by Dedieu, Stéphane, Mazères, Germain, Cottin, Patrick, Brustis, Jean-Jacques

“…The myogenic factors, MyoD, myogenin, Myf5 and MRF4, can activate skeletal muscle differentiation when overexpressed in non-muscular cells. Gene targeting…”
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Biologically active milli-calpain associated with caveolae is involved in a spatially compartmentalised signalling involving protein kinase C alpha and myristoylated alanine-rich C-kinase substrate (MARCKS) by Goudenege, Sébastien, Poussard, Sylvie, Dulong, Sandrine, Cottin, Patrick

“…We have previously shown that calpain promotes myoblast fusion by acting on protein kinase C-alpha and the cytosolic phosphorylated form of MARCKS. In other…”
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Investigation of Peroxiredoxin IV as a Calpain-regulated Pathway in Cancer by ROUMES, Hélène, PIRES-ALVES, Amélie, GONTHIER-MAURIN, Lea, DARGELOS, Elise, COTTIN, Patrick

“…Peroxiredoxin IV (Prx IV), a member of the peroxiredoxin family, has been shown to be involved in cell protection against radiation. Peroxiredoxins are also…”
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Investigation of Peroxiredoxin IV as a Calpain-regulated Pathway in Cancer by Roumes, Hélène, Pires-Alves, Amélie, Gonthier-Maurin, Léa, Dargelos, Elise, Cottin, Patrick

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