Search Results - "Cottier, Karissa"

Pathophysiology and neurologic sequelae of cerebral malaria by Schiess, Nicoline, Villabona-Rueda, Andres, Cottier, Karissa E, Huether, Katherine, Chipeta, James, Stins, Monique F

“…Cerebral malaria (CM), results from Plasmodium falciparum infection, and has a high mortality rate. CM survivors can retain life-long post CM sequelae,…”
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Micropatterned primary hepatocyte co-culture (HEPATOPAC) for fatty liver disease modeling and drug screening by Cottier, Karissa E., Bhalerao, Devika, Lewis, Candice, Gaffney, Jeannemarie, Heyward, Scott A.

“…Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, progressive disorder and growing public health concern. To address this issue considerable…”
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Impact of donor diversity on phase I and phase II activities in cryopreserved human hepatocytes and human liver microsomes by Bohl, Christopher, Brouwer, Kenneth, Heyward, Scott, Cottier, Karissa, Noah, Courtney, Ogilvie, Brian

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A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors by François-Moutal, Liberty, Wang, Yue, Moutal, Aubin, Cottier, Karissa E., Melemedjian, Ohannes K., Yang, Xiaofang, Wang, Yuying, Ju, Weina, Largent-Milnes, Tally M., Khanna, May, Vanderah, Todd W., Khanna, Rajesh

“…Targeting proteins within the N-type voltage-gated calcium channel (CaV2.2) complex has proven to be an effective strategy for developing novel pain…”
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P35 - The use of primary cryopreserved human hepatocytes as a model for non-alcoholic fatty liver disease (NAFLD) related changes in phase I and phase II enzyme activities by Cottier, Karissa, Le, Xuan, Heyward, Scott

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Sex hormones regulate NHE1 functional expression and brain endothelial proteome to control paracellular integrity of the blood endothelial barrier by Blawn, Kiera T., Kellohen, Kathryn L., Galloway, Emily A., Wahl, Jared, Vivek, Anjali, Verkhovsky, Vani G., Barker, Natalie K., Cottier, Karissa E., Vallecillo, Tissiana G., Langlais, Paul R., Liktor-Busa, Erika, Vanderah, Todd W., Largent-Milnes, Tally M.

“…•Sex hormones differential regulate NHE1 to influence pH.•Paracellular uptake is enhanced during high testosterone.•Progesterone plays a role in paracellular…”
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17-β-Estradiol induces spreading depression and pain behavior in alert female rats by Sandweiss, Alexander J, Cottier, Karissa E, McIntosh, Mary I, Dussor, Gregory, Davis, Thomas P, Vanderah, Todd W, Largent-Milnes, Tally M

“…Test the putative contribution of 17-β-estradiol in the development of spreading depression (SD) events and head pain in awake, non-restrained rats. Female,…”
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Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome by Wahl, Jared R, Vivek, Anjali, Palomino, Seph M, Almuslim, Moyad, Cottier, Karissa E, Langlais, Paul R, Streicher, John M, Vanderah, Todd W, Liktor-Busa, Erika, Largent-Milnes, Tally M

“…Pathologies of the blood-brain barrier (BBB) have been linked to a multitude of central nervous system (CNS) disorders whose pathology is poorly understood…”
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Noxa in rheumatic diseases: present understanding and future impact by Cottier, Karissa E, Fogle, Elise M, Fox, David A, Ahmed, Salahuddin

“…Impaired programmed cell death is an important contributing mechanism in the development of chronic inflammatory and autoimmune diseases. Overexpression of…”
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Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery by Cottier, Karissa E, Galloway, Emily A, Calabrese, Elisa C, Tome, Margaret E, Liktor-Busa, Erika, Kim, John, Davis, Thomas P, Vanderah, Todd W, Largent-Milnes, Tally M

“…Cortical spreading depression (CSD) in the CNS is suggested as a common mechanism contributing to headache. Despite strong evidence for CNS involvement in…”
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(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 by Moutal, Aubin, François-Moutal, Liberty, Perez-Miller, Samantha, Cottier, Karissa, Chew, Lindsey Anne, Yeon, Seul Ki, Dai, Jixun, Park, Ki Duk, Khanna, May, Khanna, Rajesh

“…The neuronal circuit remodels during development as well as in human neuropathologies such as epilepsy. Neurite outgrowth is an obligatory step in these…”
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Role of Sex Hormones in Regulation of Sodium‐Proton Exchanger NHE1: Implications for Migraine by Galloway, Emily A., Cottier, Karissa E., Kim, John, Vallecillo, Tissiana, Davis, Thomas P., Vanderah, Todd W., Largent‐Milnes, Tally M.

“…Migraine is the most common neurological disorder, affecting approximately 11% of the world population. Because women comprise over 75% of the migraineur…”
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The Effect of Cortical Spreading Depression Induced Episodic Headache on Blood-brain Barrier Structure and Function by Cottier, Karissa E

“…Previous research has demonstrated that BBB structure and function are altered as a result of various neurological disorders including ischemic stroke,…”
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