Search Results - "Cotter, Aoife G."
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COVID-19 induces a hyperactive phenotype in circulating platelets
Published in PLoS biology (17-02-2021)“…Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to…”
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Post-COVID care delivery: The experience from an Irish tertiary centre's post-COVID clinic
Published in PloS one (11-08-2023)“…The long-term effects of SARS-CoV-2 infection and optimal follow-up approach are not well-recognised. Here we describe the implementation of a post-COVID…”
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Assessing the impact of COVID-19 at 1-year using the SF-12 questionnaire: Data from the Anticipate longitudinal cohort study
Published in International journal of infectious diseases (01-05-2022)“…•Those patients with post–COVID-19 syndrome (PoCS) had reduced 12-item Short Form Survey (SF-12) scores at 1-year.•Those with ≥5 symptoms at initial diagnosis…”
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Relative contribution of HIV infection, demographics and body mass index to bone mineral density
Published in AIDS (London) (10-09-2014)“…Low bone mineral density (BMD) is common in HIV-positive patients, although the role played by HIV infection versus sociodemographic and metabolic factors…”
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Predictors of longitudinal change in bone mineral density in a cohort of HIV-positive and negative patients
Published in AIDS (London) (13-03-2017)“…OBJECTIVE:Although low bone mineral density (BMD) is prevalent in HIV, changes in BMD over time remain unclear. We aimed to compare rates of, and factors…”
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Impact of vaccination and variants of concern on long COVID clinical phenotypes
Published in BMC infectious diseases (16-11-2023)“…Abstract Background Defining patterns of symptoms in long COVID is necessary to advance therapies for this heterogeneous condition. Here we aimed to describe…”
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Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity
Published in Frontiers in immunology (16-05-2023)“…Dysregulated immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus…”
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Assessment of trabecular bone score, an index of bone microarchitecture, in HIV positive and HIV negative persons within the HIV UPBEAT cohort
Published in PloS one (21-03-2019)“…Increased prevalence of low bone mineral density (BMD) and increased fracture incidence are observed in persons living with HIV (PLWH). The trabecular bone…”
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Early inflammatory profiles predict maximal disease severity in COVID-19: An unsupervised cluster analysis
Published in Heliyon (15-08-2024)“…The inflammatory changes that underlie the heterogeneous presentations of COVID-19 remain incompletely understood. In this study we aimed to identify…”
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Endocrine complications of human immunodeficiency virus infection: Hypogonadism, bone disease and tenofovir-related toxicity
Published in Baillière's best practice & research. Clinical endocrinology & metabolism (01-06-2011)“…Treatment with highly active antiretroviral therapy (HAART) has revolutionized care of patients with HIV infection. The cost of increased survival has been…”
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Routine Hematological Parameters May Be Predictors of COVID-19 Severity
Published in Frontiers in medicine (16-07-2021)“…To date, coronavirus disease 2019 (COVID-19) has affected over 100 million people globally. COVID-19 can present with a variety of different symptoms leading…”
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Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4 + :CD8 + T-cell ratio in treated HIV-1 infection
Published in AIDS research and therapy (15-04-2020)“…The objectives of this study were to investigate the relationships between polymorphisms at the interferon lambda (IFNL) locus and CD4 :CD8 ratio normalisation…”
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General practice attendances among patients attending a post-COVID-19 clinic: a pilot study
Published in BJGP open (01-06-2021)“…About 10-35% of people with COVID-19 need medical care within 3 weeks of infection. However, the prevalence of ongoing care needs among those experiencing…”
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Rapid and Laboratory SARS-CoV-2 Antibody Testing in High-Risk Hospital Associated Cohorts of Unknown COVID-19 Exposure, a Validation and Epidemiological Study After the First Wave of the Pandemic
Published in Frontiers in medicine (26-08-2021)“…Objective: We aimed to use SARS-CoV-2 antibody tests to assess the asymptomatic seroprevalence of individuals in high-risk hospital cohorts who's previous…”
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Tenofovir and bone health
Published in Current opinion in HIV & AIDS (01-05-2016)“…PURPOSE OF REVIEWWith continued improvements to the antiviral efficacy and tolerability of antiretroviral therapy, long-term safety of antiretroviral therapy…”
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Investigating the effect of antiretroviral switch to tenofovir alafenamide on lipid profiles in people living with HIV
Published in AIDS (London) (01-07-2020)“…BACKGROUND:Whilst reporting improved renal and bone safety profiles, studies have noted changes in lipid profiles among people living with HIV (PLWH) receiving…”
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Outcome of a patient with refractory Hodgkin lymphoma on pembrolizumab, infected with SARS‐CoV‐2
Published in British journal of haematology (01-07-2020)Get full text
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HIV infection and bone disease: implications for an aging population
Published in Sexual health (01-01-2011)“…Now more than ever, the management of age-related problems, from cardiovascular morbidity to bone pathology, is increasingly relevant for HIV physicians. Low…”
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Associations between host microbiome and inflammation suggest role for host microbiome in driving COVID-19 disease severity
Published in Microbes and infection (01-03-2024)“…Systemic inflammation and innate immune activation are associated with COVID-19 disease severity. Knowledge gaps remain in the relationships between…”
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Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination
Published in Journal of immunological methods (01-11-2022)“…Measurement of quantitative antibody responses are increasingly important in evaluating the immune response to infection and vaccination. In this study we…”
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