Search Results - "Cotta, Claudiu"
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Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
Published in The Journal of clinical investigation (01-10-2018)“…Nucleophosmin (NPM1) is among the most frequently mutated genes in acute myeloid leukemia (AML). It is not known, however, how the resulting oncoprotein mutant…”
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Patients with Classic Hodgkin Lymphoma and Follicular Lymphoma Compared to Single Malignancy Controls
Published in The American journal of surgical pathology (01-08-2024)“…Classic Hodgkin lymphoma (CHL) can arise in patients with low-grade B-cell lymphoma. The features of CHL arising in follicular lymphoma (FL) and its outcome…”
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Formalin Fixation Followed by Paraffin Embedding Allows Long-Term Storage of Proteins for Liquid Chromatography-Tandem Mass Spectrometry Analysis
Published in Laboratory investigation (01-10-2023)“…In an anatomical pathology laboratory, liquid chromatography-tandem mass spectrometry (LC-MS/MS) is used to characterize amyloid deposits identified in…”
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Pathology Residents as Testing Personnel in the Hematology Laboratory: Developing Entrustable Professional Activities
Published in Archives of pathology & laboratory medicine (1976) (01-07-2022)“…Context.-Clinical laboratories and the training of pathology residents are tightly regulated environments. Compliance with regulatory requirements must be…”
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Amyloid in the breast: retrospective review with clinicopathological and radiological correlation of 32 cases from a single institution
Published in Histopathology (01-07-2021)“…Aims Mammary amyloid is an uncommon and easily overlooked pathological diagnosis with ambivalent presentation. Herein, we delineate the clinicopathological and…”
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IgA plasma cell neoplasms are characterized by poorer long-term survival and increased genomic complexity compared to IgG neoplasms
Published in Annals of diagnostic pathology (01-02-2020)“…The characteristics of the IgA plasma cell neoplasms are not clearly reported in the literature. The main goal of this study is to examine IgA plasma cell…”
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Extranodal Marginal Zone Lymphoma of the Central Nervous System Includes Parenchymal-Based Cases With Characteristic Features
Published in American journal of clinical pathology (01-07-2020)“…Abstract Objectives To define the clinicopathologic features of extranodal marginal zone lymphoma (EMZL) of the central nervous system (CNS), including cases…”
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Pathology Residents as Testing Personnel in the Hematology Laboratory
Published in Archives of pathology & laboratory medicine (1976) (01-07-2022)“…Context.— Clinical laboratories and the training of pathology residents are tightly regulated environments. Compliance with regulatory requirements must be…”
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Myeloid Sarcoma Involving the Testis in Adults: Clonal Evolution of Acute Myeloid Leukemia
Published in Applied immunohistochemistry & molecular morphology (01-04-2022)“…To describe the clinical, histologic, immunophenotypic, and genetic characteristics of myeloid sarcoma (MS) diagnosed in the testes of adults, 3 cases were…”
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Ultrasensitive automated RNA in situ hybridization for kappa and lambda light chain mRNA detects B-cell clonality in tissue biopsies with performance comparable or superior to flow cytometry
Published in Modern pathology (01-03-2018)“…The assessment of B-cell clonality is a critical component of the evaluation of suspected lymphoproliferative disorders, but analysis from formalin-fixed,…”
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T‐cell large granular lymphocytic leukemia associated with inclusion body myositis
Published in International journal of laboratory hematology (01-02-2022)Get full text
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Very rare Burkitt lymphoma with plasmacytoid differentiation, initial presentation as a CNS tumor, and poor prognosis
Published in International journal of laboratory hematology (01-06-2022)Get full text
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Ocular Adnexal Amyloidosis: A Mass Spectrometric Analysis
Published in American journal of ophthalmology (01-09-2018)“…Ocular adnexal amyloidosis (OAA) may represent localized manifestation of an underlying systemic process. Accurate identification of the amyloid fibrils can…”
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Thrombocytosis and STAT5 activation in chronic myelogenous leukaemia are not associated with JAK2 V617F or calreticulin mutations
Published in Journal of clinical pathology (01-08-2016)“…Marked thrombocytosis is uncommon in chronic myelogenous leukaemia (CML) but may be associated with mutation of JAK2 V617F, calreticulin (CALR) and/or…”
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The utility of the BIOMED-2 primers in the detection of 2 clonal, B-lymphoproliferative disorders simultaneously involving the same site
Published in Archives of pathology & laboratory medicine (1976) (01-11-2013)“…Molecular tests for clonality performed on atypical lymphoid lesions may yield abnormal results because of the coexistence of monoclonal B lymphocytosis or…”
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A Phase II Trial of Imatinib Mesylate as Maintenance Therapy for Patients With Newly Diagnosed C-kit–positive Acute Myeloid Leukemia
Published in Clinical lymphoma, myeloma and leukemia (01-02-2021)“…Adults with acute myeloid leukemia (AML) have a high rate of remission; however, more than 50% relapse. C-kit is expressed in approximately 60% of patients…”
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Intravascular T‐cell lymphoma: A rare, poorly characterized entity with cytotoxic phenotype
Published in Neuropathology (01-08-2017)“…Intravascular T‐cell lymphomas are rare, poorly characterized lesions. We discuss the clinical, radiologic and especially the laboratory characteristics of a…”
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Dendritic Cell Markers and PD-L1 are Expressed in Mediastinal Gray Zone Lymphoma
Published in Applied immunohistochemistry & molecular morphology (01-11-2018)“…Mediastinal gray zone lymphoma (MGZL) is a rare entity with morphologic, immunophenotypic, and genetic features intermediate between classic Hodgkin lymphoma…”
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Myelodysplastic Syndrome With inv(3)(q21 q26-2) or t(3;3)(q21;q26.2) Has a High Risk for Progression to Acute Myeloid Leukemia
Published in American journal of clinical pathology (01-08-2011)“…Acute myeloid leukemia (AML) with inv(3) (q21q26.2) or t(3;3)(q21;q26.2) is a distinct subtype in the World Health Organization classification. The natural…”
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