Search Results - "Coto Montes, Ana"

A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes by Tomás-Zapico, Cristina, Coto-Montes, Ana

“…:  Melatonin, the main secretory product of the pineal gland, is known to collaborate against oxidative stress within cells, but its mechanism of action in…”
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Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin by Rosales-Corral, Sergio A., Acuña-Castroviejo, Dario, Coto-Montes, Ana, Boga, Jose A., Manchester, Lucien C., Fuentes-Broto, Lorena, Korkmaz, Ahmet, Ma, Shuran, Tan, Dun- Xian, Reiter, Russel J.

“…:  Alzheimer’s disease (AD) is a highly complex neurodegenerative disorder of the aged that has multiple factors which contribute to its etiology in terms of…”
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Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol by Cristòfol, Rosa, Porquet, David, Corpas, Rubén, Coto-Montes, Ana, Serret, Jofre, Camins, Antoni, Pallàs, Mercè, Sanfeliu, Coral

“…:  The senescence‐accelerated prone 8 (SAMP8) mouse strain shows early cognitive loss that mimics the deterioration of learning and memory in the elderly and…”
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Cell interactome in sarcopenia during aging by González‐Blanco, Laura, Bermúdez, Manuel, Bermejo‐Millo, Juan C., Gutiérrez‐Rodríguez, José, Solano, Juan J., Antuña, Eduardo, Menéndez‐Valle, Iván, Caballero, Beatriz, Vega‐Naredo, Ignacio, Potes, Yaiza, Coto‐Montes, Ana

“…Background The diversity between the muscle cellular interactome of dependent and independent elderly people is based on the interrelationships established…”
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Circadian rhythms, oxidative stress, and antioxidative defense mechanisms by Hardeland, Rüdiger, Coto-Montes, Ana, Poeggeler, Burkhard

“…Endogenous circadian and exogenously driven daily rhythms of antioxidative enzyme activities and of low molecular weight antioxidants (LMWAs) are described in…”
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Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model by Gutierrez-Cuesta, Javier, Tajes, Marta, Jiménez, Andrés, Coto-Montes, Ana, Camins, Antoni, Pallàs, Mercè

“…:  We examined the effect of melatonin on pro‐survival processes in three groups of mice. Untreated senescence‐accelerated mice (SAMP8), melatonin‐treated…”
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Melatonin: an ancient molecule that makes oxygen metabolically tolerable by Manchester, Lucien C., Coto-Montes, Ana, Boga, Jose Antonio, Andersen, Lars Peter H., Zhou, Zhou, Galano, Annia, Vriend, Jerry, Tan, Dun-Xian, Reiter, Russel J.

“…Melatonin is remarkably functionally diverse with actions as a free radical scavenger and antioxidant, circadian rhythm regulator, anti‐inflammatory and…”
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Therapeutic potential of melatonin related to its role as an autophagy regulator: A review by Boga, Jose A., Caballero, Beatriz, Potes, Yaiza, Perez‐Martinez, Zulema, Reiter, Russel J., Vega‐Naredo, Ignacio, Coto‐Montes, Ana

“…There are several pathologies, syndromes, and physiological processes in which autophagy is involved. This process of self‐digestion that cells trigger as a…”
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Melatonin induces neural SOD2 expression independent of the NF-kappaB pathway and improves the mitochondrial population and function in old mice by García-Macia, Marina, Vega-Naredo, Ignacio, De Gonzalo-Calvo, David, Rodríguez-González, Susana M., Camello, Pedro J., Camello-Almaraz, Cristina, Martín-Cano, Francisco E., Rodríguez-Colunga, María J., Pozo, María J., Coto-Montes, Ana M.

“…:  Aging is commonly defined as a physiological phenomenon associated with morphological and functional deleterious changes in which oxidative stress has a…”
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Melatonin alters cell death processes in response to age-related oxidative stress in the brain of senescence-accelerated mice by Caballero, Beatriz, Vega-Naredo, Ignacio, Sierra, Verónica, Huidobro-Fernández, Covadonga, Soria-Valles, Clara, De Gonzalo-Calvo, David, Tolivia, Delio, Pallás, Mercé, Camins, Antonio, Rodríguez-Colunga, María Josefa, Coto-Montes, Ana

“…:  We studied the effect of age and melatonin on cell death processes in brain aging. Senescence‐accelerated prone mice 8 (SAMP8) and senescence‐accelerated…”
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Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8 by Gutierrez-Cuesta, Javier, Sureda, Francesc X., Romeu, Marta, Canudas, Anna M., Caballero, Beatriz, Coto-Montes, Ana, Camins, Antoni, Pallàs, Mercè

“…:  Certain effects of melatonin on senescence were investigated. The experimental model used was 10‐month‐old senescence‐accelerated mouse prone 8 (SAMP8). The…”
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Inflammaging: Implications in Sarcopenia by Antuña, Eduardo, Cachán-Vega, Cristina, Bermejo-Millo, Juan Carlos, Potes, Yaiza, Caballero, Beatriz, Vega-Naredo, Ignacio, Coto-Montes, Ana, Garcia-Gonzalez, Claudia

“…In a world in which life expectancy is increasing, understanding and promoting healthy aging becomes a contemporary demand. In the elderly, a sterile, chronic…”
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Chronic inflammation as predictor of 1-year hospitalization and mortality in elderly population by de Gonzalo-Calvo, David, de Luxán-Delgado, Beatriz, Martínez-Camblor, Pablo, Rodríguez-González, Susana, García-Macia, Marina, Suárez, Francisco M., Solano, Juan J., Rodríguez-Colunga, María J., Coto-Montes, Ana

“…Eur J Clin Invest 2012; 42 (10): 1037–1046 Background  Systemic low‐grade inflammation is thought to be associated with an increased risk of adverse clinical…”
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Effect of Melatonin on Herpesvirus Type 1 Replication by Pérez-Martínez, Zulema, Boga, Jose Antonio, Potes, Yaiza, Melón, Santiago, Coto-Montes, Ana

“…Acute HSV-1 infection is associated with mild symptoms, such as fever and lesions of the mouth, face and skin. This phase is followed by a latency period…”
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Melatonin as a Potential Agent in the Treatment of Sarcopenia by Coto-Montes, Ana, Boga, Jose A, Tan, Dun X, Reiter, Russel J

“…Considering the increased speed at which the world population is aging, sarcopenia could become an epidemic in this century. This condition currently has no…”
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Role of melatonin in the regulation of autophagy and mitophagy: A review by Coto-Montes, Ana, Boga, Jose Antonio, Rosales-Corral, Sergio, Fuentes-Broto, Lorena, Tan, Dun-Xian, Reiter, Russel J.

“…► The role of melatonin in the regulation of autophagy and mitophagy. ► The molecular mechanisms by which melatonin influences apoptosis. ► The function of…”
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Benefits of the Neurogenic Potential of Melatonin for Treating Neurological and Neuropsychiatric Disorders by Potes, Yaiza, Cachán-Vega, Cristina, Antuña, Eduardo, García-González, Claudia, Menéndez-Coto, Nerea, Boga, Jose Antonio, Gutiérrez-Rodríguez, José, Bermúdez, Manuel, Sierra, Verónica, Vega-Naredo, Ignacio, Coto-Montes, Ana, Caballero, Beatriz

“…There are several neurological diseases under which processes related to adult brain neurogenesis, such cell proliferation, neural differentiation and neuronal…”
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Melatonin Alleviates Liver Mitochondrial Dysfunction in Leptin-Deficient Mice by de Luxán-Delgado, Beatriz, Potes, Yaiza, Rubio-González, Adrian, Solano, Juan José, Boga, José Antonio, Antuña, Eduardo, Cachán-Vega, Cristina, Bermejo-Millo, Juan Carlos, Menéndez-Coto, Nerea, García-González, Claudia, Pereira, Gonçalo C, Caballero, Beatriz, Coto-Montes, Ana, Vega-Naredo, Ignacio

“…Despite efforts to elucidate the cellular adaptations induced by obesity, cellular bioenergetics is currently considered a crucial target. New strategies to…”
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NLRP3 Contributes to Sarcopenia Associated to Dependency Recapitulating Inflammatory-Associated Muscle Degeneration by Antuña, Eduardo, Potes, Yaiza, Baena-Huerta, Francisco Javier, Cachán-Vega, Cristina, Menéndez-Coto, Nerea, Álvarez Darriba, Eva, Fernández-Fernández, Marta, Burgos Bencosme, Natalie, Bermúdez, Manuel, López Álvarez, Eva María, Gutiérrez-Rodríguez, José, Boga, José Antonio, Caballero, Beatriz, Vega-Naredo, Ignacio, Coto-Montes, Ana, Garcia-Gonzalez, Claudia

“…Sarcopenia, a complex and debilitating condition characterized by progressive deterioration of skeletal muscle, is the primary cause of age-associated…”
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Chronic Treatment with Melatonin Improves Hippocampal Neurogenesis in the Aged Brain and Under Neurodegeneration by Cachán-Vega, Cristina, Vega-Naredo, Ignacio, Potes, Yaiza, Bermejo-Millo, Juan Carlos, Rubio-González, Adrian, García-González, Claudia, Antuña, Eduardo, Bermúdez, Manuel, Gutiérrez-Rodríguez, José, Boga, José Antonio, Coto-Montes, Ana, Caballero, Beatriz

“…Adult hippocampal neurogenesis is altered during aging and under different neuropsychiatric and neurodegenerative diseases. Melatonin shows neurogenic and…”
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