Search Results - "Cotinot, C."

Refine Results
  1. 1

    Timing of Maternal Exposure and Foetal Sex Determine the Effects of Low-level Chemical Mixture Exposure on the Foetal Neuroendocrine System in Sheep by Bellingham, M., Fowler, P. A., MacDonald, E. S., Mandon-Pepin, B., Cotinot, C., Rhind, S., Sharpe, R. M., Evans, N. P.

    Published in Journal of neuroendocrinology (01-12-2016)
    “…We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA…”
    Get full text
    Journal Article
  2. 2
  3. 3

    Reproduction Symposium: does grazing on biosolids-treated pasture pose a pathophysiological risk associated with increased exposure to endocrine disrupting compounds? by Evans, N P, Bellingham, M, Sharpe, R M, Cotinot, C, Rhind, S M, Kyle, C, Erhard, H, Hombach-Klonisch, S, Lind, P M, Fowler, P A

    Published in Journal of animal science (01-08-2014)
    “…Biosolids (processed human sewage sludge), which contain low individual concentrations of an array of contaminants including heavy metals and organic…”
    Get full text
    Journal Article
  4. 4

    Foetal Hypothalamic and Pituitary Expression of Gonadotrophin-Releasing Hormone and Galanin Systems is Disturbed by Exposure to Sewage Sludge Chemicals via Maternal Ingestion by Bellingham, M., Fowler, P. A., Amezaga, M. R., Whitelaw, C. M., Rhind, S. M., Cotinot, C., Mandon-Pepin, B., Sharpe, R. M., Evans, N. P.

    Published in Journal of neuroendocrinology (01-06-2010)
    “…Animals and humans are chronically exposed to endocrine disrupting chemicals (EDCs) that are ubiquitous in the environment. There are strong circumstantial…”
    Get full text
    Journal Article
  5. 5

    Effects of environmental pollutants on the reproduction and welfare of ruminants by Rhind, S. M., Evans, N. P., Bellingham, M., Sharpe, R. M., Cotinot, C., Mandon-Pepin, B., Loup, B., Sinclair, K. D., Lea, R. G., Pocar, P., Fischer, B., van der Zalm, E., Hart, K., Schmidt, J.-S., Amezaga, M. R., Fowler, P. A.

    Published in Animal (Cambridge, England) (01-07-2010)
    “…Anthropogenic pollutants comprise a wide range of synthetic organic compounds and heavy metals, which are dispersed throughout the environment, usually at low…”
    Get full text
    Journal Article
  6. 6

    REPRODUCTION SYMPOSIUM: Does grazing on biosolids-treated pasture pose a pathophysiological risk associated with increased exposure to endocrine disrupting compounds?1,2 by Evans, N. P., Bellingham, M., Sharpe, R. M., Cotinot, C., Rhind, S. M., Kyle, C., Erhard, H., Hombach-Klonisch, S., Lind, P. M., Fowler, P. A.

    Published in Journal of animal science (01-08-2014)
    “…Biosolids (processed human sewage sludge), which contain low individual concentrations of an array of contaminants including heavy metals and organic…”
    Get full text
    Journal Article
  7. 7

    Foetal and post-natal exposure of sheep to sewage sludge chemicals disrupts sperm production in adulthood in a subset of animals by Bellingham, M., McKinnell, C., Fowler, P. A., Amezaga, M. R., Zhang, Z., Rhind, S. M., Cotinot, C., Mandon-Pepin, B., Evans, N. P., Sharpe, R. M.

    Published in International journal of andrology (01-06-2012)
    “…Summary Exposure to ubiquitous, environmental chemicals (ECs) has been hypothesized as a cause for declining male reproductive health. Understanding the…”
    Get full text
    Journal Article
  8. 8

    Reverse transcription-polymerase chain reaction analysis of genes involved in gonadal differentiation in pigs by Parma, P, Pailhoux, E, Cotinot, C

    Published in Biology of reproduction (01-09-1999)
    “…In mammals, testis development is initiated in the embryo as a response to the expression of the sex-determining gene, SRY. The time course of SRY expression…”
    Get full text
    Journal Article
  9. 9

    Effects of Exposure to Environmental Chemicals During Pregnancy on the Development of the Male and Female Reproductive Axes by Bellingham, M, Fiandanese, N, Byers, A, Cotinot, C, Evans, NP, Pocar, P, Amezaga, MR, Lea, RG, Sinclair, KD, Rhind, SM, Fowler, PA

    Published in Reproduction in Domestic Animals (01-08-2012)
    “…There is a large body of literature describing effects of environmental chemicals (ECs), many of them anthropogenic with endocrine‐disrupting properties, on…”
    Get full text
    Journal Article Conference Proceeding
  10. 10

    Expression studies of the PIS-regulated genes suggest different mechanisms of sex determination within mammals by Pannetier, M, Servel, N, Cocquet, J, Besnard, N, Cotinot, C, Pailhoux, E

    Published in Cytogenetic and genome research (01-01-2003)
    “…In mammals, the Y-located SRY gene is known to induce testis formation from the indifferent gonad. A related gene, SOX9, also plays a critical role in testis…”
    Get more information
    Journal Article
  11. 11

    Attempt to rescue sex-reversal by transgenic expression of the PISRT1 gene in XX PIS-/- goats by Boulanger, L, Kocer, A, Daniel, N, Pannetier, M, Chesné, P, Heyman, Y, Renault, L, Mandon-Pépin, B, Chavatte-Palmer, P, Vignon, X, Vilotte, J-L, Cotinot, C, Renard, J-P, Pailhoux, E

    Published in Sexual development (01-01-2008)
    “…The Polled Intersex Syndrome (PIS mutation) in goats leads to an absence of horn and to an early sex-reversal of the XX gonads. This mutation is a deletion of…”
    Get more information
    Journal Article
  12. 12
  13. 13

    A case of intersexuality in pigs associated with a de novo paracentric inversion 9 (p1.2; p2.2) by Pinton, A., Pailhoux, E., Piumi, F., Rogel-Gaillard, C., Darré, R., Yerle, M., Ducos, A., Cotinot, C.

    Published in Animal genetics (01-02-2002)
    “…In several mammalian species, genetic defects can be responsible for the interruption of and/or the deviation from the sequential steps of normal gonadal…”
    Get full text
    Journal Article
  14. 14

    Relevance of intersexuality to breeding and reproductive biotechnology programs; XX sex reversal in pigs by Pailhoux, E., Pelliniemi, L., Barbosa, A., Parma, P., Kuopio, T., Cotinot, C.

    Published in Theriogenology (1997)
    “…In pigs, the frequency of intersexuality ranges from 0.1 to 0.6%. Economic losses are significant and result from sterility, urogenital infections and…”
    Get full text
    Journal Article
  15. 15

    Sequence evolution of SRY gene within Bovidae family by Payen, E J, Cotinot, C Y

    Published in Mammalian genome (01-11-1994)
    “…In mammals, male sex determination requires a dominant factor provided by the Y Chromosome (Chr). The SRY gene corresponds to this key factor and is conserved…”
    Get full text
    Journal Article
  16. 16

    Mapping in pig of genes involved in sexual differentiation: AMH, WT1, FTZF1, SOX2, SOX9, AHC, and placental and embryonic CYP19 by Lahbib-Mansais, Y, Barbosa, A, Yerle, M, Parma, P, Milan, D, Pailhoux, E, Gellin, J, Cotinot, C

    Published in Cytogenetics and cell genetics (01-01-1997)
    “…Intersexuality has been reported in pigs and investigations are in progress to identify and physically map the genes involved in sex-reversal. In this study we…”
    Get more information
    Journal Article
  17. 17

    Molecular analysis of 60,XX pseudohermaphrodite polled goats for the presence of SRY and ZFY genes by Pailhoux, E, Cribiu, E P, Chaffaux, S, Darre, R, Fellous, M, Cotinot, C

    Published in Journal of reproduction & fertility (01-03-1994)
    “…The polled mutation is characterized by a recessive, incompletely penetrant, hermaphroditic effect associated with the dominant genetic factor responsible for…”
    Get full text
    Journal Article
  18. 18

    Genetic mapping of the polled/intersex locus (PIS) in goats by Vaiman, D., Pailhoux, E., Schibler, L., Oustry, A., Chaffaux, S., Cotinot, C., Fellous, M., Cribiu, E.P.

    Published in Theriogenology (1997)
    “…Sex determination in mammals is due to a complex cascade of gene regulations involving SRY and autosomal and X genes. Study of intersex cases in domestic…”
    Get full text
    Journal Article
  19. 19

    Detection and characterization of a mutation in the porcine DAX1 gene by Parma, P, Pailhoux, E, Cotinot, C

    Published in Animal genetics (01-10-1998)
    “…Allelic frequency: Seventeen unrelated animals were analyzed and only two showed the presence of the deleted sequence. Mendelian inheritance: X-linked…”
    Get full text
    Journal Article
  20. 20

    Comparative HMG-box sequences of the SRY gene between sheep, cattle and goats by Payen, Emmanuel J., Cotinot, Corinne Y.

    Published in Nucleic acids research (11-06-1993)
    “…In mammals, sexual differentiation of the gonads during development depends on the presence of the Y chromosome. The testis-determining gene lies on the Y…”
    Get full text
    Journal Article