Heightened sensitivity of the esophagus to radiation in a patient with AIDS

Esophageal stricture is an uncommon complication in HIV-negative patients treated with radiation to the chest for lung cancer. There have been a number of recent reports on the association of cancer and HIV-positive patients, as well as a greater sensitivity to radiation therapy of the mucous membra...

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Bibliographic Details
Published in:	The American journal of gastroenterology Vol. 90; no. 5; p. 812
Main Authors:	Costleigh, B J, Miyamoto, C T, Micaily, B, Brady, L W
Format:	Journal Article
Language:	English
Published:	United States 01-05-1995
Subjects:	Acquired Immunodeficiency Syndrome - complications Esophageal Stenosis - etiology Esophagus - radiation effects Humans Lung Neoplasms - complications Lung Neoplasms - radiotherapy Male Middle Aged Radiation Injuries - etiology Radiation Tolerance
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Summary:	Esophageal stricture is an uncommon complication in HIV-negative patients treated with radiation to the chest for lung cancer. There have been a number of recent reports on the association of cancer and HIV-positive patients, as well as a greater sensitivity to radiation therapy of the mucous membranes in HIV/AIDS patients. This article reflects a review of the literature on the risk of major complications and morbidity of the esophagus in HIV+/AIDS patients whose chests are treated with radiation for lung cancer. Included is a report of a previously unpublished case of an early and severe esophageal reaction to radiation therapy in an AIDS patient.
ISSN:	0002-9270
DOI:	10.1111/j.1572-0241.1995.tb09326.x