Search Results - "Costeloe, K."
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Perinatal outcomes for extremely preterm babies in relation to place of birth in England: the EPICure 2 study
Published in Archives of disease in childhood. Fetal and neonatal edition (01-05-2014)“…Expertise and resources may be important determinants of outcome for extremely preterm babies. We evaluated the effect of place of birth and perinatal transfer…”
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Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
Published in Nature communications (09-03-2020)“…Infection and infection-related complications are important causes of death and morbidity following preterm birth. Despite this risk, there is limited…”
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Identifying immune signatures of sepsis to increase diagnostic accuracy in very preterm babies
Published in Nature communications (09-01-2024)“…Bacterial infections are a major cause of mortality in preterm babies, yet our understanding of early-life disease-associated immune dysregulation remains…”
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EPICure: facts and figures: why preterm labour should be treated
Published in BJOG : an international journal of obstetrics and gynaecology (01-12-2006)“…The principal objective of the EPICure studies was to determine both short‐ and long‐term outcomes of extremely preterm birth. Data were collected for all…”
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Intravenous antibiotics in preterm infants have a negative effect upon microbiome development throughout preterm life
Published in Gut pathogens (21-04-2023)“…Intestinal dysbiosis is implicated in the origins of necrotising enterocolitis and late-onset sepsis in preterm babies. However, the effect of modulators of…”
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Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies
Published in BMJ (Online) (04-12-2012)“…Objective To determine outcomes at age 3 years in babies born before 27 completed weeks’ gestation in 2006, and to evaluate changes in outcome since 1995 for…”
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Respiratory health in pre-school and school age children following extremely preterm birth
Published in Archives of disease in childhood (01-12-2008)“…Rationale: Increasing survival at extremely low gestational ages is associated with very high rates of bronchopulmonary dysplasia (BPD) but is rarely…”
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Probiotics for preterm infants?
Published in Archives of disease in childhood. Fetal and neonatal edition (01-09-2003)“…Infants nursed in special care baby units develop an abnormal pattern of microbial colonisation, which may contribute to disease. Enteric feeding of live…”
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Journal Article Book Review -
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Association of prematurity, lung disease and body size with lung volume and ventilation inhomogeneity in unsedated neonates: a multicentre study
Published in Thorax (01-03-2009)“…Previous studies have suggested that preterm birth with or without subsequent chronic lung disease is associated with reduced functional residual capacity…”
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Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies)
Published in BMJ (Online) (04-12-2012)“…Objective To determine survival and neonatal morbidity for babies born between 22 and 26 weeks’ gestation in England during 2006, and to evaluate changes in…”
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The EPICure study: growth and associated problems in children born at 25 weeks of gestational age or less
Published in Archives of disease in childhood. Fetal and neonatal edition (01-11-2003)“…Aim: To define growth outcomes of a geographically defined population of extremely preterm babies. Population: The EPICure study identified all surviving…”
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Decision making and modes of death in a tertiary neonatal unit
Published in Archives of disease in childhood. Fetal and neonatal edition (01-11-2004)“…Aims: To study the frequency and reason for withdrawal/withholding of life sustaining treatment (LST) and do not resuscitate (DNR) orders in infants who died…”
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Low birth weight for gestation and airway function in infancy: exploring the fetal origins hypothesis
Published in Thorax (01-01-2004)“…Background: Poor fetal growth has been associated with impaired airway function in adult life, but evidence linking birth weight and airway function in early…”
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An investigation into the reporting and management of late terminations of pregnancy (between 22+0 and 26+6 weeks of gestation) within NHS Hospitals in England in 2006: the EPICure preterm cohort study
Published in BJOG : an international journal of obstetrics and gynaecology (01-05-2012)“…Please cite this paper as: Draper E, Alfirevic Z, Stacey F, Hennessy E, Costeloe K, for the EPICure Study Group. An investigation into the reporting and…”
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Perinatal Outcomes for Extremely Preterm Babies in Relation to Place of Birth in England: The EPICure 2 Study
Published in Obstetrical & gynecological survey (01-10-2014)“…ABSTRACTExtremely premature babies bear the highest risk for significant mortality and morbidity. This study was performed to evaluate the hypothesis that…”
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Are deficits of arachidonic and docosahexaenoic acids responsible for the neural and vascular complications of preterm babies?
Published in The American journal of clinical nutrition (01-10-1997)“…We review evidence suggesting that pre- or postnatal deficits of arachidonic acid (AA) and docosahexaenoic acid (DHA) together with underdeveloped antioxidant…”
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Journal Article Conference Proceeding -
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PS-184 Intestinal Permeability Preceding Necrotising Enterocolitis And Sepsis In Preterm Infants
Published in Archives of disease in childhood (01-10-2014)“…IntroductionIncreased intestinal permeability may precede the onset of several important diseases in preterm infants including necrotising enterocolitis (NEC)…”
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PO-0536 Circulating Bacterial Dna And Lipopolysaccharide Preceding Necrotising Enterocolitis In Preterm Infants
Published in Archives of disease in childhood (01-10-2014)“…Abstract only…”
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The nutrient intakes of mothers of low birth weight babies - a comparison of ethnic groups in East London, UK
Published in Maternal and child nutrition (01-04-2005)“…The objective of this paper was to compare the nutrient intakes of mothers of different ethnic origins after they had given birth to a low birth weight (LBW)…”
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Pneumatocoele and conjunctivitis in a newborn
Published in The Lancet (British edition) (30-10-2004)“…(S Fang FRCPCH, R Bagtharia FRCPCH, R KumarMBBS, Prof K L Costeloe FRCPCH) Royal Brompton Hospital NHS Trust (A Bush FRCPCH) Barts and the London N HS Trust (M…”
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