Search Results - "Costello, M."
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1
Mitigating incentive conflicts in inter-firm relationships: Evidence from long-term supply contracts
Published in Journal of accounting & economics (01-07-2013)“…Using a sample of long-term supply contracts collected from SEC filings, I show that hold-up concerns and information asymmetry are important determinants of…”
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2
Circadian Rhythm, Clock Genes, and Hypertension: Recent Advances in Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-11-2021)“…Accumulating evidence suggests that the molecular circadian clock is crucial in blood pressure (BP) control. Circadian rhythms are controlled by the central…”
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3
The cause and consequence of fiber cell compaction in the vertebrate lens
Published in Experimental eye research (01-03-2017)“…Fiber cells of the ocular lens are arranged in a series of concentric shells. New growth shells are added continuously to the lens surface and, as a…”
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4
Age-related increases in reaction time result from slower preparation, not delayed initiation
Published in Journal of neurophysiology (01-09-2022)“…Previous research argues that older adults have slower response times because they hesitate to react, favoring accuracy over speed. The present results…”
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5
Predicting future grizzly bear habitat use in the Bitterroot Ecosystem under recolonization and reintroduction scenarios
Published in PloS one (04-09-2024)“…Many conservation actions must be implemented with limited data. This is especially true when planning recovery efforts for extirpated populations, such as…”
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6
Acral Melanoma and Mechanical Stress on the Plantar Surface of the Foot
Published in The New England journal of medicine (27-07-2017)“…A Mayo Clinic analysis of melanoma distribution showed a high frequency of lesions on the heel and fewer lesions on the front of the foot than shown in a…”
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7
Risk and Protective Factors Associated With Trajectories of Depressed Mood From Adolescence to Early Adulthood
Published in Journal of consulting and clinical psychology (01-04-2008)“…This study used semi-parametric group-based modeling to explore unconditional and conditional trajectories of self-reported depressed mood from ages 12 to 25…”
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Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue‐specific biomatrix scaffolds
Published in Hepatology (Baltimore, Md.) (01-01-2011)“…Current protocols for differentiation of stem cells make use of multiple treatments of soluble signals and/or matrix factors and result typically in partial…”
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9
Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-2016)“…Defects in clearing apoptotic debris disrupt tissue and immunological homeostasis, leading to autoimmune and inflammatory diseases. Herein, we report that…”
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10
Identification and Ultrastructural Characterization of a Novel Nuclear Degradation Complex in Differentiating Lens Fiber Cells
Published in PloS one (18-08-2016)“…An unresolved issue in structural biology is how the encapsulated lens removes membranous organelles to carry out its role as a transparent optical element. In…”
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11
Novel mitochondrial derived Nuclear Excisosome degrades nuclei during differentiation of prosimian Galago (bush baby) monkey lenses
Published in PloS one (12-11-2020)“…The unique cellular organization and transparent function of the ocular lens depend on the continuous differentiation of immature epithelial cells on the lens…”
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12
Evidence-based guideline: unexplained infertility
Published in Human reproduction (Oxford) (03-10-2023)“…Abstract STUDY QUESTION What is the recommended management for couples presenting with unexplained infertility (UI), based on the best available evidence in…”
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13
Time-Varying Effect Models for Examining Age-Dynamic Associations in Gerontological Research
Published in Experimental aging research (27-05-2023)“…Dynamic processes unfolding over later adulthood are of prime interest to gerontological researchers. Time-varying effect modeling (TVEM) accommodates dynamic…”
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14
Circulating microRNAs as potential markers of human drug‐induced liver injury
Published in Hepatology (Baltimore, Md.) (01-11-2011)“…New biomarkers of liver injury are required in the clinic and in preclinical pharmaceutical evaluation. Previous studies demonstrate that two liver‐enriched…”
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15
Synthetic small intestinal scaffolds for improved studies of intestinal differentiation
Published in Biotechnology and bioengineering (01-06-2014)“…ABSTRACT In vitro intestinal models can provide new insights into small intestinal function, including cellular growth and proliferation mechanisms, drug…”
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16
Tight Glycemic Control versus Standard Care after Pediatric Cardiac Surgery
Published in The New England journal of medicine (27-09-2012)“…This trial tested the hypothesis that tight glycemic control reduces morbidity after pediatric cardiac surgery. Results indicated that this therapy, as…”
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Molecular mechanism of respiratory syncytial virus fusion inhibitors
Published in Nature chemical biology (01-02-2016)“…The binding of small-molecule inhibitors of the RSV F glycoprotein in a central cavity in the prefusion conformation stabilizes this conformation and blocks…”
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Older Adults without Desired Surrogates in a Nationally Representative Sample
Published in Journal of the American Geriatrics Society (JAGS) (01-01-2021)“…BACKGROUND/OBJECTIVES Little is known about older adults who have intact capacity but do not have a desired surrogate to make decisions if their capacity…”
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19
Perceptual decision making in less than 30 milliseconds
Published in Nature neuroscience (01-03-2010)“…It is hard to dissociate the time taken for purely perceptual processes from motor reaction times when making responses to stimuli. Using a combination of a…”
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The role of FYCO1-dependent autophagy in lens fiber cell differentiation
Published in Autophagy (02-09-2022)“…FYCO1 (FYVE and coiled-coil domain containing 1) is an adaptor protein, expressed ubiquitously and required for microtubule-dependent, plus-end-directed…”
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