Search Results - "Costello, Caitlin"

Newly diagnosed multiple myeloma: making sense of the menu by Costello, Caitlin L

“…The development of new drugs and subsequent novel combinations for the treatment of newly diagnosed multiple myeloma (NDMM) has resulted in a plethora of…”
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Social Media and Substance Use: What Should We Be Recommending to Teens and Their Parents? by Costello, Caitlin R., M.D, Ramo, Danielle E., Ph.D

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42.2 Clinical Challenges in Diagnosis and Treatment of Early Psychosis and Comorbidities by Costello, Caitlin R.

“…Early psychosis-related disorders profoundly impact our young patients’ functioning, developmental trajectories, and overall well-being, and clinical…”
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15.4 Legal Issues Facing Unaccompanied Minors, Asylum Seekers, and Mixed Status Families by Costello, Caitlin R.

“…Unaccompanied minors and families with mixed status must navigate a complex legal system. For child and adolescent psychiatrists to be fully equipped to help…”
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62.1 Legal Risks and Protection for Young People Interacting Online by Costello, Caitlin R.

“…The increasing investment of young people in social media brings with it many mental health and legal risks, including cyberbullying, exposure to online…”
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Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial by Voorhees, Peter M., Kaufman, Jonathan L., Laubach, Jacob, Sborov, Douglas W., Reeves, Brandi, Rodriguez, Cesar, Chari, Ajai, Silbermann, Rebecca, Costa, Luciano J., Anderson, Larry D., Nathwani, Nitya, Shah, Nina, Efebera, Yvonne A., Holstein, Sarah A., Costello, Caitlin, Jakubowiak, Andrzej, Wildes, Tanya M., Orlowski, Robert Z., Shain, Kenneth H., Cowan, Andrew J., Murphy, Sean, Lutska, Yana, Pei, Huiling, Ukropec, Jon, Vermeulen, Jessica, de Boer, Carla, Hoehn, Daniela, Lin, Thomas S., Richardson, Paul G.

“…Lenalidomide, bortezomib, and dexamethasone (RVd) followed by autologous stem cell transplantation (ASCT) is standard frontline therapy for transplant-eligible…”
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Treatment of Multiple Myeloma: ASCO and CCO Joint Clinical Practice Guideline by Mikhael, Joseph, Ismaila, Nofisat, Cheung, Matthew C, Costello, Caitlin, Dhodapkar, Madhav V, Kumar, Shaji, Lacy, Martha, Lipe, Brea, Little, Richard F, Nikonova, Anna, Omel, James, Peswani, Namrata, Prica, Anca, Raje, Noopur, Seth, Rahul, Vesole, David H, Walker, Irwin, Whitley, Alexander, Wildes, Tanya M, Wong, Sandy W, Martin, Tom

“…To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others. ASCO and Cancer Care Ontario convened an…”
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Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial by Bahlis, Nizar J., Costello, Caitlin L., Raje, Noopur S., Levy, Moshe Y., Dholaria, Bhagirathbhai, Solh, Melhem, Tomasson, Michael H., Damore, Michael A., Jiang, Sibo, Basu, Cynthia, Skoura, Athanasia, Chan, Edward M., Trudel, Suzanne, Jakubowiak, Andrzej, Gasparetto, Cristina, Chu, Michael P., Dalovisio, Andrew, Sebag, Michael, Lesokhin, Alexander M.

“…Multiple myeloma (MM) is a plasma cell malignancy expressing B cell maturation antigen (BCMA). Elranatamab, a bispecific antibody, engages BCMA on MM and CD3…”
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Daratumumab with lenalidomide as maintenance after transplant in newly diagnosed multiple myeloma: the AURIGA study by Badros, Ashraf Z, Foster, Laahn, Anderson, Jr, Larry D, Chaulagain, Chakra P, Pettijohn, Erin M, Cowan, Andrew J, Costello, Caitlin L, Larson, Sarah, Sborov, Douglas W, Shain, Kenneth H, Silbermann, Rebecca, Shah, Nina, Chung, Alfred, Krevvata, Maria, Pei, Huiling, Patel, Sharmila, Khare, Vipin, Cortoos, Annelore, Carson, Robin, Lin, Thomas, Voorhees, Peter M

“…No randomized trial has directly compared daratumumab and lenalidomide (D-R) maintenance therapy versus standard-of-care lenalidomide (R) alone…”
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Management of patients with multiple myeloma beyond the clinical-trial setting: understanding the balance between efficacy, safety and tolerability, and quality of life by Terpos, Evangelos, Mikhael, Joseph, Hajek, Roman, Chari, Ajai, Zweegman, Sonja, Lee, Hans C., Mateos, María-Victoria, Larocca, Alessandra, Ramasamy, Karthik, Kaiser, Martin, Cook, Gordon, Weisel, Katja C., Costello, Caitlin L., Elliott, Jennifer, Palumbo, Antonio, Usmani, Saad Z.

“…Treatment options in multiple myeloma (MM) are increasing with the introduction of complex multi-novel-agent-based regimens investigated in randomized clinical…”
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Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma by Lazzari, Elisa, Mondala, Phoebe K., Santos, Nathaniel Delos, Miller, Amber C., Pineda, Gabriel, Jiang, Qingfei, Leu, Heather, Ali, Shawn A., Ganesan, Anusha-Preethi, Wu, Christina N., Costello, Caitlin, Minden, Mark, Chiaramonte, Raffaella, Stewart, A.  Keith, Crews, Leslie A., Jamieson, Catriona H. M.

“…Despite novel therapies, relapse of multiple myeloma (MM) is virtually inevitable. Amplification of chromosome 1q, which harbors the inflammation-responsive…”
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A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation by Davids, Matthew S., Kim, Haesook T., Costello, Caitlin, Herrera, Alex F., Locke, Frederick L., Maegawa, Rodrigo O., Savell, Alexandra, Mazzeo, Michael, Anderson, Adrienne, Boardman, Alexander P., Weber, Augustine, Avigan, David, Chen, Yi-Bin, Nikiforow, Sarah, Ho, Vincent T., Cutler, Corey, Alyea, Edwin P., Bachireddy, Pavan, Wu, Catherine J., Ritz, Jerome, Streicher, Howard, Ball, Edward D., Bashey, Asad, Soiffer, Robert J., Armand, Philippe

“…Programmed cell death-1 (PD-1)/programmed death ligand-1 blockade may potentially augment graft-vs-tumor effects following allogeneic hematopoietic cell…”
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Uh-Oh: How Teens Get Into Trouble Online and What We Can Do About It by Costello, Caitlin R., Leventhal, Bennett L.

“…Social media use is integral to the lives of young people, bringing both enrichment and exposure to social, mental health, and legal risks. We aim to…”
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A CD10‐negative adult B‐lymphoblastic leukaemia with amplification of KMT2A without rearrangement: A case report and review of the English literature by Wang, Huan‐You, Louis, Hailee M. St, Costello, Caitlin L., Murray, Sarah S., Dell'Aquila, Marie L.

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The interplay of GTP-binding protein AGB1 with ER stress sensors IRE1a and IRE1b modulates Arabidopsis unfolded protein response and bacterial immunity by Afrin, Taiaba, Costello, Caitlin N., Monella, Amber N., Kørner, Camilla J., Pajerowska-Mukhtar, Karolina M.

“…In eukaryotic cells, the accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) results in ER stress that induces a cascade of…”
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Screen Time and Obsessive-Compulsive Disorder Among Children 9–10 Years Old: A Prospective Cohort Study by Nagata, Jason M., Chu, Jonathan, Zamora, Gabriel, Ganson, Kyle T., Testa, Alexander, Jackson, Dylan B., Costello, Caitlin R., Murray, Stuart B., Baker, Fiona C.

“…The aim of this study is to determine the prospective associations between baseline screen time and obsessive-compulsive disorder (OCD) at 2-year follow-up in…”
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Real-world comparative effectiveness of triplets containing bortezomib (B), carfilzomib (C), daratumumab (D), or ixazomib (I) in relapsed/refractory multiple myeloma (RRMM) in the US by Davies, Faith, Rifkin, Robert, Costello, Caitlin, Morgan, Gareth, Usmani, Saad, Abonour, Rafat, Palumbo, Antonio, Romanus, Dorothy, Hajek, Roman, Terpos, Evangelos, Cherepanov, Dasha, Stull, Dawn Marie, Huang, Hui, Leleu, Xavier, Berdeja, Jesus, Lee, Hans C., Weisel, Katja, Thompson, Michael, Boccadoro, Mario, Zonder, Jeffrey, Cook, Gordon, Puig, Noemi, Vela-Ojeda, Jorge, Farrelly, Eileen, Raju, Aditya, Blazer, Marlo, Chari, Ajai

“…Multiple available combinations of proteasome inhibitors, immunomodulators (IMIDs), and monoclonal antibodies are shifting the relapsed/refractory multiple…”
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Ibrutinib alone or with dexamethasone for relapsed or relapsed and refractory multiple myeloma: phase 2 trial results by Richardson, Paul G., Bensinger, William I., Huff, Carol Ann, Costello, Caitlin L., Lendvai, Nikoletta, Berdeja, Jesus G., Anderson, Larry D., Siegel, David S., Lebovic, Daniel, Jagannath, Sundar, Laubach, Jacob P., Stockerl‐Goldstein, Keith E., Kwei, Long, Clow, Fong, Elias, Laurence, Salman, Zeena, Graef, Thorsten, Bilotti, Elizabeth, Vij, Ravi

“…Summary Novel therapies with unique new targets are needed for patients who are relapsed/refractory to current treatments for multiple myeloma. Ibrutinib is a…”
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Ixazomib-lenalidomide-dexamethasone in routine clinical practice: effectiveness in relapsed/refractory multiple myeloma by Hájek, Roman, Minařík, Jiří, Straub, Jan, Pour, Luděk, Jungova, Alexandra, Berdeja, Jesus G, Boccadoro, Mario, Brozova, Lucie, Spencer, Andrew, Rhee, Frits van, Vela-Ojeda, Jorge, Thompson, Michael A, Abonour, Rafat, Chari, Ajai, Cook, Gordon, Costello, Caitlin L, Davies, Faith E, Hungria, Vania Tm, Lee, Hans C, Leleu, Xavier, Puig, Noemi, Rifkin, Robert M, Terpos, Evangelos, Usmani, Saad Z, Weisel, Katja C, Zonder, Jeffrey A, Bařinová, Magda, Kuhn, Matyáš, Šilar, Jiří, Čápková, Lenka, Galvez, Kenny, Lu, Jin, Elliott, Jennifer, Stull, Dawn Marie, Ren, Kaili, Maisnar, Vladimír

“…To evaluate the effectiveness and safety of ixazomib-lenalidomide-dexamethasone (IRd) in relapsed/refractory multiple myeloma in routine clinical practice…”
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Adolescents and Social Media: Privacy, Brain Development, and the Law by Costello, Caitlin R, McNiel, Dale E, Binder, Renée L

“…Adolescents under the age of 18 are not recognized in the law as adults, nor do they have the fully developed capacity of adults. Yet teens regularly enter…”
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