Solfeggio-frequency music exposure reverses cognitive and endocrine deficits evoked by a 24-h light exposure in adult zebrafish

Solfeggio-frequency music exposure reverses cognitive and endocrine deficits evoked by a 24-h light exposure in adult zebrafish

Music therapy has long been used as a non-pharmacological intervention to improve cognitive function and mood in humans. Mounting rodent evidence also supports beneficial impact of music exposure on animal cognitive performance. The zebrafish (Danio rerio) is an important emerging aquatic animal mod...

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Bibliographic Details
Published in:Behavioural brain research Vol. 450; p. 114461
Main Authors: dos Santos, Amanda C., de Abreu, Murilo S., de Mello, Gabriel P., Costella, Vanusa, do Amaral, Nicoli R., Zanella, Alexander, Poletto, Júlia, Petersen, Elena V., Kalueff, Allan V., Giacomini, Ana C.V.V.
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 26-07-2023
Subjects:
Adult
Affect
Animals
Behavior, Animal
Circadian rhythm
Cognition
Cortisol
Humans
Models, Animal
Music
Music exposure
Zebrafish
Zebrafish - physiology
Music exposure
Zebrafish
Cognition
Cortisol
Circadian rhythm
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Summary:Music therapy has long been used as a non-pharmacological intervention to improve cognitive function and mood in humans. Mounting rodent evidence also supports beneficial impact of music exposure on animal cognitive performance. The zebrafish (Danio rerio) is an important emerging aquatic animal model in translational biomedical and neuroscience research. Here, we evaluate the effects of intermittent (2-h or 6-h twice daily) and continuous (24-h) solfeggio-frequency music exposure on behavioral, cognitive and endocrine parameters in adult zebrafish whose circadian rhythm was disturbed by a 24-h light exposure. Overall, a 24-h light exposure stress evokes overt cognitive deficits in the inhibitory avoidance test and elevates zebrafish whole-body cortisol levels. However, these effects were reversed by solfeggio-frequency music exposure for 2 or 6 h twice daily, and by continuous 24-h exposure. Collectively, these findings suggest a positive modulation of cognitive and endocrine responses in adult zebrafish by environmental enrichment via the long-term exposure to music, and reinforces zebrafish as a robust, sensitive model organism for neurocognitive and neuroendocrine research.
Bibliography:ObjectType-Article-1
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content type line 23
ISSN:0166-4328
1872-7549
DOI:10.1016/j.bbr.2023.114461