Search Results - "Costea, Daniela‐Elena"
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α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration
Published in Cancers (01-06-2019)“…Integrin α11β1 is a collagen receptor that has been reported to be overexpressed in the stroma of non-small cell lung cancer (NSCLC) and of head and neck…”
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Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better?
Published in Journal of oral pathology & medicine (01-08-2020)“…Background Numerous studies have been presented on histological grading of oral squamous cell carcinomas (OSCC) for predicting survival, but uncertainty of…”
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Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction
Published in International journal of molecular sciences (22-04-2023)“…We aimed to investigate whether molecular clues from the extracellular matrix (ECM) can induce oral epithelial differentiation of pluripotent stem cells. Mouse…”
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Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1
Published in Cancer research (Chicago, Ill.) (15-11-2010)“…Stem cells are permanent residents of tissues and thought to be targets of cancer initiation. The frequent, and often early, upregulation of the FOXM1…”
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Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues
Published in Stem cell research & therapy (09-08-2023)“…Induced pluripotent stem cells (iPS) can be generated from various somatic cells and can subsequently be differentiated to multiple cell types of the body…”
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MicroRNA-138 Abates Fibroblast Motility With Effect on Invasion of Adjacent Cancer Cells
Published in Frontiers in oncology (17-03-2022)“…Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in…”
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Knowledge, opinions, and practices related to oral cancer prevention and oral mucosal examination among dentists in Moldova, Belarus and Armenia: a multi-country cross-sectional study
Published in BMC oral health (18-12-2021)“…Moldova, Belarus, and Armenia are post-Soviet countries with a high rate of heavy smokers and a relatively high age-standardized incidence of oral cancer…”
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The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(-) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients
Published in Biomedicines (26-06-2023)“…Somatic mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. To study mutations relative to the…”
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Epithelial PD‐L1 expression at tumor front predicts overall survival in a cohort of oral squamous cell carcinomas from Sudan
Published in Clinical and experimental dental research (01-12-2022)“…Background We recently described the tumor immune microenvironment (TIME) in oral squamous cell carcinomas (OSCC) from Sudan by assessing the core of the…”
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Investigation of Cross-Reactivity of Anti-Ephrin-B2 Antibody to Other Ephrin-B Members in an Immunohistochemical Study in a Cohort of Oral Squamous Cell Carcinoma
Published in Oral (Basel, Switzerland) (01-01-2022)“…Ephrin-B1,-B2 and -B3 proteins share a high degree of sequence similarity. Investigation of these proteins as putative prognostic markers in human cancers…”
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Isolation and characterization of cells derived from human epithelial rests of Malassez
Published in Odontology (01-07-2019)“…[Abstract] The epithelial rests of Malassez (ERMs) might represent a valuable source of oral epithelial cells with stem cell properties. The purpose of this…”
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Oral Tongue Malignancies in Autoimmune Polyendocrine Syndrome Type 1
Published in Frontiers in endocrinology (Lausanne) (17-08-2018)“…Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) or Autoimmune polyendocrine syndrome type-1 (APS-1) (APECED, OMIM 240300) is a rare,…”
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Cancer Stem Cells in Squamous Cell Carcinoma Switch between Two Distinct Phenotypes That Are Preferentially Migratory or Proliferative
Published in Cancer research (Chicago, Ill.) (01-08-2011)“…Epithelial-to-mesenchymal transition (EMT) is an important driver of tumor invasion and metastasis, which causes many cancer deaths. Cancer stem cells (CSC)…”
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Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography
Published in PloS one (27-09-2018)“…Extracellular vesicles (EVs) are a heterogeneous population of biological particles released by cells. They represent an attractive source of potential…”
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MicroRNAs as Important Players and Biomarkers in Oral Carcinogenesis
Published in BioMed research international (01-01-2015)“…Oral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide. The number of new OSCC cases…”
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Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics
Published in PloS one (04-09-2020)“…Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of…”
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Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma
Published in EBioMedicine (01-02-2016)“…Cancer stem cells (CSCs) drive tumour spread and therapeutic resistance, and can undergo epithelial-to-mesenchymal transition (EMT) and…”
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Analysis of Salivary Mycobiome in a Cohort of Oral Squamous Cell Carcinoma Patients From Sudan Identifies Higher Salivary Carriage of Malassezia as an Independent and Favorable Predictor of Overall Survival
Published in Frontiers in cellular and infection microbiology (12-10-2021)“…Background Microbial dysbiosis and microbiome-induced inflammation have emerged as important factors in oral squamous cell carcinoma (OSCC) tumorigenesis…”
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MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma
Published in PloS one (22-11-2011)“…MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation in oral squamous cell carcinoma (OSCC)…”
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Heterogeneity of cancer-associated fibroblasts and tumor-promoting roles in head and neck squamous cell carcinoma
Published in Frontiers in molecular biosciences (20-06-2024)“…Tumor microenvironment (TME) in head and neck squamous cell carcinoma (HNSCC) has a major influence on disease progression and therapy response. One of the…”
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