Search Results - "Costas, Mónica A"

Extract from Aloysia polystachya Induces the Cell Death of Colorectal Cancer Stem Cells by Soares Machado, Mileni, Palma, Alejandra, Panelo, Laura C., Paz, Leonardo A., Rosa, Francisco, Lira, María Cecilia, Azurmendi, Pablo, Rubio, María F., Lenz, Guido, Urtreger, Alejandro J., Costas, Mónica A.

“…Cancer stem cells (CSCs) are an important player in the resistance of cancers to therapy. In this work, we determined the flavonoids composition and biological…”
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NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes by Molinero, Luciana L, Fuertes, Mercedes B, Girart, María Victoria, Fainboim, Leonardo, Rabinovich, Gabriel A, Costas, Mónica A, Zwirner, Norberto W

“…MHC class I-related chain A gene (MICA) is a stress-regulated, HLA-related molecule which exhibits a restricted pattern of expression. MICA protein is…”
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Imatinib resistance in multidrug-resistant K562 human leukemic cells by Assef, Yanina, Rubio, Fernanda, Coló, Georgina, del Mónaco, Silvana, Costas, Mónica A, Kotsias, Basilio A

“…Abstract The multidrug resistance phenotype (MDR) is one of the major causes of failure in cancer chemotherapy and it is associated with the over-expression of…”
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Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1 by Toscano, Marta A., Campagna, Leonardo, Molinero, Luciana L., Cerliani, Juan P., Croci, Diego O., Ilarregui, Juan M., Fuertes, Mercedes B., Nojek, Ignacio M., Fededa, Juan P., Zwirner, Norberto W., Costas, Mónica A., Rabinovich, Gabriel A.

“…► Activated and differentiated T cells express high amounts of galectin-1. ► The NF-κB signaling pathway controls galectin-1 expression. ► LGALS1 gene is a…”
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Cyclin D1 is a NF-κB corepressor by Rubio, María F., Fernandez, Pablo N. Larrosa, Alvarado, Cecilia V., Panelo, L.C., Grecco, Marina Ruiz, Colo, Georgina P., Martínez-Noel, Giselle A., Micenmacher, Sabrina M., Costas, Mónica A.

“…NF-κB regulates the expression of Cyclin D1 (CD1), while RAC3 is an NF-κB coactivator that enhances its transcriptional activity. In this work, we investigated…”
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The inflammatory cytokine TNF contributes with RAC3-induced malignant transformation by Machado, Mileni Soares, Rosa, Francisco D, Lira, María C, Urtreger, Alejandro J, Rubio, María F, Costas, Mónica A

“…RAC3 is a coactivator of steroid receptors and NF-κB. It is usually overexpressed in several tumors, contributes to maintain cancer stem cells and also to…”
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GPR75 receptor mediates 20-HETE-signaling and metastatic features of androgen-insensitive prostate cancer cells by Cárdenas, Sofia, Colombero, Cecilia, Panelo, Laura, Dakarapu, Rambabu, Falck, John R., Costas, Monica A., Nowicki, Susana

“…Recent studies have shown that 20-hydroxyeicosatetraenoic acid (20-HETE) is a key molecule in sustaining androgen-mediated prostate cancer cell survival. Thus,…”
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NCoA3 upregulation in breast cancer‑associated adipocytes elicits an inflammatory profile by Lira, María Cecilia, Rosa, Francisco D, Aiello, Ignacio, Machado, Mileni Soares, Palma, Alejandra G, Paz, Leonardo, Güemes, María Cecilia Salazar, Burlando, Silvia, Azurmendi, Pablo J, Paladino, Natalia, Costas, Mónica A, Rubio, María Fernanda

“…Nuclear receptor coactivator 3 (NCoA3) is a transcriptional coactivator of NF‑κB and other factors, which is expressed at relatively low levels in normal cells…”
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Megakaryocyte–stromal cell interactions: Effect on megakaryocyte proliferation, proplatelet production, and survival by Goette, Nora P., Borzone, Francisco R., Discianni Lupi, Ailen D., Chasseing, Norma A., Rubio, María F., Costas, Mónica A., Heller, Paula G., Marta, Rosana F., Lev, Paola R.

“…•Stromal cells have differential effects on sequential steps of megakaryocyte development.•HUVECs and human skin fibroblasts enhance megakaryocyte…”
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High RAC3 expression levels are required for induction and maintaining of cancer cell stemness by Panelo, Laura C, Machado, Mileni Soares, Rubio, María F, Jaworski, Felipe, Alvarado, Cecilia V, Paz, Leonardo A, Urtreger, Alejandro J, Vazquez, Elba, Costas, Mónica A

“…RAC3 is a transcription coactivator, usually overexpressed in several tumors and required to maintain the pluripotency in normal stem cells. In this work we…”
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Suprachiasmatic astrocytes as an interface for immune-circadian signalling by Leone, María Juliana, Marpegan, Luciano, Bekinschtein, Tristán A., Costas, Mónica A., Golombek, Diego A.

“…The hypothalamic suprachiasmatic nuclei (SCN), the site of a mammalian circadian clock, exhibit a dense immunoreactivity for glial fibrillary acidic protein…”
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Toxoplasma gondii Hsp90 is a Potential Drug Target Whose Expression and Subcellular Localization are Developmentally Regulated by Echeverria, Pablo C., Matrajt, Mariana, Harb, Omar S., Zappia, María P., Costas, Monica A., Roos, David S., Dubremetz, Jean François, Angel, Sergio O.

“…Two replicative forms characterize the asexual cycle of the protozoan parasite Toxoplasma gondii: rapidly growing tachyzoites and slowly dividing encysted…”
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RAC3 down-regulation sensitizes human chronic myeloid leukemia cells to TRAIL-induced apoptosis by Colo, Georgina P., Rosato, Roberto R., Grant, Steven, Costas, Mónica A.

“…The nuclear receptor coactivator RAC3 plays important roles in many biological processes and tumorigenesis. We found that RAC3 is over-expressed in human…”
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Rapamycin effect on senescence and autophagy processes in human cell lines by Fernández Larrosa, Pablo N, Ruiz Grecco, Marina, Alvarado, Cecilia V, Micenmacher, Sabrina, Aguirre, Cristina, Martínez Noel, Giselle, Costas, Mónica A, Rubio, María Fernanda

“…Autophagy and senescence are both processes that firstly avoid tumor development through the inhibition of proliferation of damaged cells. However, autophagy…”
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Activation of Signaling Lymphocytic Activation Molecule Triggers a Signaling Cascade That Enhances Th1 Responses in Human Intracellular Infection by Quiroga, Maria F, Martinez, Gustavo J, Pasquinelli, Virginia, Costas, Monica A, Bracco, Maria M, Malbran, Alejandro, Olivares, Liliana M, Sieling, Peter A, Garcia, Veronica E

“…T cell production of IFN-gamma contributes to host defense against infection by intracellular pathogens, including mycobacteria. Lepromatous leprosy, the…”
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Autophagy. A strategy for cell survival by Costas, Mónica A, Rubio, María F

“…Autophagy is a process of recycling parts of the cell. As described in this review, it occurs naturally in order to preserve cells from the accumulation of…”
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Circadian responses to endotoxin treatment in mice by Marpegán, Luciano, Bekinschtein, Tristán A., Costas, Monica A., Golombek, Diego A.

“…We tested the ability of Escherichia coli lipopolysaccharide (LPS) to phase-shift the activity circadian rhythm in C57Bl/6J mice. Intraperitoneal…”
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RAC3 overexpression is a transforming and proliferative signal that contributes to tumoral development by Alvarado, Cecilia V, Micenmacher, Sabrina, Ruiz Grecco, Marina, Rubio, Maria F, Fernandez Larrosa, Nicolas, Costas, Monica A

“…RAC3 has been firstly characterized as a nuclear receptor coactivator that is found in limited amounts in normal cells, but is over-expressed in tumors and is…”
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The steroid receptor co-activator-1 (SRC-1) potentiates TGF-β/Smad signaling : role of p300/CBP by DENNLER, Sylviane, PENDARIES, Valérie, TACHEAU, Charlotte, COSTAS, Monica A, MAUVIEL, Alain, VERRECCHIA, Franck

“…The three related 160-kDa proteins, SRC-1, TIF-2 and RAC-3, were initially identified as factors interacting with nuclear receptors. They have also been…”
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RAC-3 is a NF-κB coactivator by Werbajh, Santiago, Nojek, Ignacio, Lanz, Rainer, Costas, Mónica A.

“…It has been shown that the molecular mechanism by which cytokines and glucocorticoids mutually antagonize their functions involves a mutual glucocorticoid…”
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