Search Results - "Costa Silva, A."

Chemical Constituents from Aerial Parts of Baccharis sphenophylla and Effects against Intracellular Forms of Trypanosoma cruzi by Silva, Matheus L., Costa‐Silva, Thais A., Antar, Guilherme M., Tempone, Andre G., Lago, João Henrique G.

“…The hexane extract from aerial parts Baccharis sphenophylla Dusén ex Malme (Asteraceae) displayed activity against amastigote forms of Trypanossoma cruzi and…”
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A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division by Amaral, Maiara, de Sousa, Fernanda S., Silva, Thais A. Costa, Junior, Andrés Jimenez G., Taniwaki, Noemi N., Johns, Deidre M., Lago, João Henrique G., Anderson, Edward A., Tempone, Andre G.

“…Leishmaniasis is a neglected disease that affects more than 12 million people, with a limited therapy. Plant-derived natural products represent a useful source…”
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Smartphone-based evaluation of static balance and mobility in type 2 Diabetes by Fernandes, Thaissianne F, Volpe, Maria Izabel T C, Pena, Francineide P S, Santos, Enzo Gabriel R, Pinto, Gustavo Henrique L, Belgamo, Anderson, Costa E Silva, Anselmo A, Cabral, André S, Callegari, Bianca, Souza, Givago S

“…It was compared smartphone-based measurements of static balance control and mobility of elderly population with and without type 2 diabetes mellitus (DM2). The…”
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Essential Oils from Different Myrtaceae Species from Brazilian Atlantic Forest Biome – Chemical Dereplication and Evaluation of Antitrypanosomal Activity by Silva Maiolini, Tatiane Cristina, Rosa, Welton, Oliveira Miranda, Daniel, Costa‐Silva, Thais A., Tempone, Andre G., Pires Bueno, Paula Carolina, Ferreira Dias, Danielle, Aparecida Chagas de Paula, Daniela, Sartorelli, Patricia, Lago, João Henrique G., Gomes Soares, Marisi

“…Chagas Disease (CD), caused by flagellate protozoan Trypanosoma cruzi, is a Neglected Tropical Diseases (NTD) that affect approximately seven million people…”
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At‐sea trialling of the Hookpod: a ‘one‐stop’ mitigation solution for seabird bycatch in pelagic longline fisheries by Sullivan, B. J., Kibel, B., Kibel, P., Yates, O., Potts, J. M., Ingham, B., Domingo, A., Gianuca, D., Jiménez, S., Lebepe, B., Maree, B. A., Neves, T., Peppes, F., Rasehlomi, T., Silva‐Costa, A., Wanless, R. M.

“…Bycatch of pelagic seabird species in longline fisheries is recognized as one of the most important and pervasive sources of mortality, contributing to an…”
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First record of Neea madeirana (Nyctaginaceae: Pisonieae) from the Peruvian Amazon by DA SILVA COSTA, Daniel, FARROÑAY, Francisco, DÁVILA-DOZA, Hilda Paulette, VILLACORTA-MORA, Lindher

“…ABSTRACT Neea is one of the largest genera of Nyctaginaceae and comprises approximately 80 species distributed in the Neotropical region. Here, we report for…”
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Saturated salt solution: a further step to a formaldehyde‐free embalming method for veterinary gross anatomy by Lombardero, M., Yllera, M. M., Costa‐e‐Silva, A., Oliveira, M. J., Ferreira, P. G.

“…In the field of veterinary anatomy, most of the specimens used in practical sessions are perfused with fixatives. Thus, they can be used for a longer time,…”
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Simplified Derivatives of Dibenzylbutyrolactone Lignans from Hydrocotyle bonariensis as Antitrypanosomal Candidates by Souza, Dalete Christine S., Costa‐Silva, Thais A., Morais, Thiago R., Brito, Juliana R., Ferreira, Edgard A., Antar, Guilherme M., Sartorelli, Patricia, Tempone, Andre G., Lago, João Henrique G.

“…The search for the pharmacophore of a bioactive compound, crucial for drug discovery studies, involves the adequate arrangement of different atoms in the…”
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γ‐Lactones from Persea americana and Persea fulva – in Vitro and in Silico Evaluation of Trypanosoma cruzi Activity by Reis, Isabella Mary A., Umehara, Eric, Conceição, Rodrigo S., M. Oliveira, Larissa, Coelho dos S. Junior, Manoelito, Costa‐Silva, Thais A., Amaral, Maiara, Tempone, Andre G., Branco, Alexsandro, Lago, João Henrique G.

“…In the present study, five known γ‐lactones (majoranolide B – 1, majorenolide – 2, majorynolide – 3, lincomolide D – 4, and isolinderanolide E – 5), as well as…”
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Disentangling the effects of insomnia and night work on cardiovascular diseases: a study in nursing professionals by Silva-Costa, A, Griep, R H, Rotenberg, L

“…Cardiovascular diseases (CVDs) are known to be associated with poor sleep quality in general populations, but they have not been consistently associated with…”
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Aporphine Alkaloids from Ocotea puberula with Anti‐Trypanosoma Cruzi Potential – Activity of Dicentrine‐β‐N‐Oxide in the Plasma Membrane Electric Potentials by Barbosa, Henrique, Costa‐Silva, Thais A., Alves Conserva, Geanne A., Araujo, Adelson J., Lordello, Ana Luísa L., Antar, Guilherme M., Amaral, Maiara, Soares, Marisi G., Tempone, Andre G., Lago, João Henrique G.

“…One new aporphine, dicentrine‐β‐N‐oxide (1), together with five related known alkaloids dehydrodicentrine (2), predicentrine (3), N‐methyllaurotetanine (4),…”
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Molar incisor hypomineralization: prevalence, severity and clinical consequences in Brazilian children by DA COSTA-SILVA, CRISTIANE MARIA, JEREMIAS, FABIANO, De SOUZA, JULIANA FELTRIN, De CÁSSIA LOIOLA CORDEIRO, RITA, SANTOS-PINTO, LOURDES, CILENSE ZUANON, ANGELA CRISTINA

“…International Journal of Paediatric Dentistry 2010; 20: 426–434 Background.  The prevalence of molar incisor hypomineralization (MIH) varies considerably…”
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Synthesis of New Dehydrodieugenol Derivatives via Olefin Cross Metathesis and In Vitro Evaluation of Their Trypanocidal Activity by Thalita S. Galhardo, Anderson K. Ueno, Wagner A. Carvalho, Thais A. Costa-Silva, Marina M. Gonçalves, Mariana B. Abiuzi, Andre G. Tempone, João Henrique G. Lago, Dalmo Mandelli, Cedric Fischmeister, Christian Bruneau

“…Ruthenium-catalyzed cross metathesis using biseugenol (1) with electron-deficient olefins methyl (2a) and ethyl (2b) acrylates, acrylic acid (2c),…”
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Enyne acetogenins from Porcelia macrocarpa displayed anti-Trypanosoma cruzi activity and cause a reduction in the intracellular calcium level by Thevenard, Fernanda, Brito, Ivanildo A., Costa-Silva, Thais A., Tempone, Andre G., Lago, João Henrique G.

“…Natural products are a promising source of new compounds with a wide spectrum of pharmacological properties, including antiprotozoal activities. Chagas…”
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Nonclinical Evaluation of Single-Mutant E. coli Asparaginases Obtained by Double-Mutant Deconvolution: Improving Toxicological, Immune and Inflammatory Responses by Ruiz-Lara, Grace, Costa-Silva, Tales A, Muso-Cachumba, Jorge Javier, Cevallos Espinel, Johanna, Fontes, Marina Gabriel, Garcia-Maya, Mitla, Rahman, Khondaker Miraz, Rangel-Yagui, Carlota de Oliveira, Monteiro, Gisele

“…Acute lymphoblastic leukaemia is currently treated with bacterial L-asparaginase; however, its side effects raise the need for the development of improved and…”
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Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae) by Costa-Silva, Thais A. da, Conserva, Geanne A. Alves, Galisteo Jr, Andrés J., Tempone, Andre G., Lago, João Henrique G.

“…BACKGROUNDVisceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong…”
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Evaluation of the effects in cellular membrane models of antitrypanosomal poly-thymolformaldehyde (PTF) using Langmuir monolayers by Parolin, Giovana A, Gonçalves, Giulia E G, Costa-Silva, Thais A, Tempone, Andre G, Caseli, Luciano, Lago, João Henrique G, Péres, Laura O

“…The polymerization of bioactive compounds may be interesting because the supramolecular structures formed can boost biological action on microorganism…”
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Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products from Nectandra leucantha by Araujo, Sheila C., Sousa, Fernanda S., Costa-Silva, Thais A., Tempone, Andre G., Lago, João Henrique G., Honorio, Kathia M.

“…In the present study, the phytochemical study of the n-hexane extract from flowers of Nectandra leucantha (Lauraceae) afforded six known neolignans (1–6) as…”
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Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses by Alves Conserva, Geanne A, Quirós-Guerrero, Luis M, Costa-Silva, Thais A, Marcourt, Laurence, Pinto, Erika G, Tempone, Andre G, Fernandes, João Paulo S, Wolfender, Jean-Luc, Queiroz, Emerson F, Lago, João Henrique G

“…EtOH extracts from the leaves and twigs of Nectandra oppositifolia Nees & Mart. shown activity against amastigote forms of Trypanosoma cruzi. These extracts…”
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Screening and optimizing fermentation production of l‐asparaginase by Aspergillus terreus strain S‐18 isolated from the Brazilian Caatinga Biome by Rocha, W.R.V., Costa‐Silva, T.A., Agamez‐Montalvo, G.S., Feitosa, V.A., Machado, S.E.F., Souza Lima, G.M., Pessoa‐, A., Alves, H.S.

“…Aims The aim of this study was to find new eukaryotic sources of the l‐asparaginase (l‐ASNase), since the prokaryotic sources of the enzyme are well‐reported…”
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