Search Results - "Costa Malheiros, Denise Maria Avancini"
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Mesenchymal Stem Cells Attenuate Renal Fibrosis Through Immune Modulation and Remodeling Properties in a Rat Remnant Kidney Model
Published in Stem cells (Dayton, Ohio) (01-12-2009)“…Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury, but their role in chronic kidney diseases is still unknown. More…”
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2
Renal Outcomes in Brazilian Patients with Immunoglobulin A Nephropathy and Cellular Crescentic Lesions
Published in Kidney & blood pressure research (01-05-2020)“…Background and Aim: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulopathy. The Oxford classification was recently updated to include…”
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3
TLR2 and TLR4 play opposite role in autophagy associated with cisplatin-induced acute kidney injury
Published in Clinical science (1979) (31-08-2018)“…Acute kidney injury (AKI) is considered an inflammatory disease in which toll-like receptors (TLRs) signaling pathways play an important role. The activation…”
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4
NLRP3 inflammasome inhibition ameliorates tubulointerstitial injury in the remnant kidney model
Published in Laboratory investigation (01-06-2018)“…Recent studies suggest that NLRP3 inflammasome activation is involved in the pathogenesis of chronic kidney disease (CKD). Allopurinol (ALLO) inhibits xanthine…”
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5
Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury
Published in Stem cell research & therapy (28-01-2017)“…Mesenchymal stromal cells (MSCs) represent an option for the treatment of acute kidney injury (AKI). It is known that young stem cells are better than are aged…”
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6
Podocytopathies associated with familial partial lipodystrophy due to LMNA variants: report of two cases
Published in Archives of Endocrinology and Metabolism (10-05-2024)“…Lipodystrophies are characterized by complete or selective loss of adipose tissue and can be acquired or inherited. Familial partial lipodystrophy (FPLD) is a…”
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Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis
Published in Frontiers in physiology (07-07-2021)“…Subjects recovering from acute kidney injury (AKI) are at risk of developing chronic kidney disease (CKD). The mechanisms underlying this transition are…”
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8
Adipose tissue-derived stem cell treatment prevents renal disease progression
Published in Cell transplantation (01-08-2012)“…Adipose tissue-derived stem cells (ASCs) are an attractive source of stem cells with regenerative properties that are similar to those of bone marrow stem…”
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Regression of albuminuria and hypertension and arrest of severe renal injury by a losartan-hydrochlorothiazide association in a model of very advanced nephropathy
Published in PloS one (19-02-2013)“…Treatments that effectively prevent chronic kidney disease (CKD) when initiated early often yield disappointing results when started at more advanced phases…”
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10
Simultaneous activation of innate and adaptive immunity participates in the development of renal injury in a model of heavy proteinuria
Published in Bioscience reports (31-08-2018)“…Protein overload of proximal tubular cells (PTCs) can promote interstitial injury by unclear mechanisms that may involve activation of innate immunity. We…”
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11
Cardiac and renal effects of liver cirrhosis in a growing animal model
Published in Acta cirúrgica brasileira (01-01-2021)“…ABSTRACT Purpose: To assess the biochemical, histological, histomorphometric and molecular effects of biliary duct ligation (BDL) induced liver cirrhosis in…”
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12
Methimazole-Induced ANCA Vasculitis: A Case Report
Published in Diagnostics (Basel) (01-09-2021)“…Rapidly progressive glomerulonephritis (RPGN) is a syndrome which presents rapid loss of renal function. Vasculitis represents one of the major causes, often…”
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13
Deletion of bradykinin B1 receptor reduces renal fibrosis
Published in International immunopharmacology (01-06-2009)“…The Kallikrein–kinin system works through activation of two receptors. One constitutive, named B2 receptor (B2R) and another inducible, denominated B1 receptor…”
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14
Cyclooxygenase-2 (COX-2) inhibition limits abnormal COX-2 expression and progressive injury in the remnant kidney
Published in Kidney international (01-12-2003)“…Cyclooxygenase-2 (COX-2) inhibition limits abnormal COX-2 expression and progressive injury in the remnant kidney. The pathogenesis of progressive…”
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15
Protective response in renal transplantation: no clinical or molecular differences between open and laparoscopic donor nephrectomy
Published in Clinics (São Paulo, Brazil) (01-04-2013)“…Prolonged warm ischemia time and increased intra-abdominal pressure caused by pneumoperitoneum during a laparoscopic donor nephrectomy could enhance renal…”
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16
Evaluation of glomerular sirtuin-1 and claudin-1 in the pathophysiology of nondiabetic focal segmental glomerulosclerosis
Published in Scientific reports (19-12-2023)“…Focal segmental glomerulosclerosis (FSGS) is the leading cause of nephrotic syndrome, which is characterized by podocyte injury. Given that the pathophysiology…”
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NF-κB System Is Chronically Activated and Promotes Glomerular Injury in Experimental Type 1 Diabetic Kidney Disease
Published in Frontiers in physiology (11-02-2020)“…High glucose concentration can activate TLR4 and NF-κB, triggering the production of proinflammatory mediators. We investigated whether the NF-κB pathway is…”
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18
Pathogenic role of innate immunity in a model of chronic NO inhibition associated with salt overload
Published in American journal of physiology. Renal physiology (01-10-2019)“…Nitric oxide inhibition with -nitro-l-arginine methyl ester (l-NAME), along with salt overload, leads to hypertension, albuminuria, glomerulosclerosis,…”
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A life-threatening case of TAFRO syndrome with dramatic response to tocilizumab, rituximab, and pulse steroids: The first case report in Latin America
Published in Medicine (Baltimore) (01-03-2017)“…This is the report of the first case of TAFRO syndrome (Thrombocytopenia, Anasarca, myelofibrosis, Renal dysfunction, Organomegaly) in Latin America. The…”
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Chronic exposure to hypoxia attenuates renal injury and innate immunity activation in the remnant kidney model
Published in American journal of physiology. Renal physiology (01-11-2019)“…Hypoxia is thought to influence the pathogenesis of chronic kidney disease, but direct evidence that prolonged exposure to tissue hypoxia initiates or…”
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