Search Results - "Costa Franco, Miriam M"

The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection by Marim, Fernanda M., Franco, Miriam M. Costa, Gomes, Marco Tulio R., Miraglia, Maria Cruz, Giambartolomei, Guillermo H., Oliveira, Sergio Costa

“…The innate immune system is essential for the detection and elimination of bacterial pathogens. Upon inflammasome activation, caspase-1 cleaves pro-IL-1β and…”
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Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation by Costa Franco, Miriam M, Marim, Fernanda, Guimarães, Erika S, Assis, Natan R G, Cerqueira, Daiane M, Alves-Silva, Juliana, Harms, Jerome, Splitter, Gary, Smith, Judith, Kanneganti, Thirumala-Devi, de Queiroz, Nina M G P, Gutman, Delia, Barber, Glen N, Oliveira, Sergio C

“…Immunity against microbes depends on recognition of pathogen-associated molecular patterns by innate receptors. Signaling pathways triggered by DNA involves…”
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Brucella abortus‐activated microglia induce neuronal death through primary phagocytosis by Rodríguez, Ana M., Delpino, M. Victoria, Miraglia, M. Cruz, Costa Franco, Miriam M., Barrionuevo, Paula, Dennis, Vida A., Oliveira, Sergio C., Giambartolomei, Guillermo H.

“…Inflammation has long been implicated as a contributor to pathogenesis in neurobrucellosis. Many of the associated neurocognitive symptoms of neurobrucellosis…”
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Modulation of Microtubule Dynamics Affects Brucella abortus Intracellular Survival, Pathogen-Containing Vacuole Maturation, and Pro-inflammatory Cytokine Production in Infected Macrophages by Alves-Silva, Juliana, Tavares, Isabela P, Guimarães, Erika S, Costa Franco, Miriam M, Figueiredo, Barbara C, Marques, João T, Splitter, Gary, Oliveira, Sergio C

“…The microtubule (MT) cytoskeleton regulates several cellular processes related to the immune system. For instance, an intricate intracellular transport…”
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Glial Cell-Elicited Activation of Brain Microvasculature in Response to Brucella abortus Infection Requires ASC Inflammasome-Dependent IL-1β Production by Miraglia, M Cruz, Costa Franco, Miriam M, Rodriguez, Ana M, Bellozi, Paula M Q, Ferrari, Carina C, Farias, Maria I, Dennis, Vida A, Barrionuevo, Paula, de Oliveira, Antonio C P, Pitossi, Fernando, Kim, Kwang Sik, Delpino, M Victoria, Oliveira, Sergio Costa, Giambartolomei, Guillermo H

“…Blood-brain barrier activation and/or dysfunction are a common feature of human neurobrucellosis, but the underlying pathogenic mechanisms are largely unknown…”
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