Search Results - "Costa Gontijo, Douglas"
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In Vitro and in Vivo Antimalarial Activity, Cytotoxicity and Phytochemical HRMS2 Profile of Plants from the Western Pará State, Brazilian Amazonia
Published in Chemistry & biodiversity (01-01-2024)“…Ethnopharmacology and botanical taxonomy are valid criteria used to selecting plants for antimalarial bioprospection purposes. Based on these two criteria,…”
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A Comprehensive View on (−)‐7‐Oxo‐ent‐kaur‐16‐en‐19‐oic Acid, the Major Constituent of Xylopia sericea Leaves Extract: Complete NMR Assignments, X‐Ray Crystallographic Structure, in Vitro Antimalarial Activity and Cytotoxicity
Published in Chemistry & biodiversity (01-07-2019)“…Bioguided fractionation of Xylopia sericea antiplasmodial dichloromethane leaves extract led to the isolation of (−)‐7‐oxo‐ent‐kaur‐16‐en‐19‐oic acid…”
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Antiplasmodial activity and cytotoxicity, isolation of active alkaloids, and dereplication of Xylopia sericea leaves ethanol extract by UPLC‐DAD‐ESI‐MS/MS
Published in Journal of pharmacy and pharmacology (01-02-2019)“…Objectives To assess the antiplasmodial activity of the ethanol extract of Xylopia sericea leaves, Annonaceae, often associated with antimalarial use and to…”
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Phytochemistry and antiplasmodial activity of Xylopia sericea leaves
Published in Natural product research (16-12-2020)“…Aiming to investigate the antiplasmodial activity and the phytochemical composition of Xylopia sericea leaves, the essential oil and dichloromethane extract…”
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In vitro antiplasmodial activity, targeted LC–MS metabolite profiling, and identification of major natural products in the bioactive extracts of Palicourea and Psychotria species from the Amazonia and Atlantic Forest biomes, Brazil
Published in Metabolomics (01-09-2021)“…Introduction A great variety of bioactive natural products has been reported for different Palicourea and Psychotria species (Rubiaceae). However, few of them…”
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Bioprospection for antiplasmodial activity, and identification of bioactive metabolites of native plants species from the Mata Atlântica biome, Brazil
Published in Natural product research (19-05-2021)“…A total of 33 extracts of eleven different plants species from Mata Atlântica biome, Brazil, and different fractions of the bioactive extracts were evaluated…”
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An update review on monoterpene indole alkaloids and biological activities of Tabernaemontana species occurring in Brazil
Published in Journal of ethnopharmacology (28-06-2024)“…The Tabernaemontana genus belongs to the Apocynaceae family of which 30 species are found in Brazil. Some Tabernaemontana species are used by Brazilian…”
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Mangifera indica leaves extract and mangiferin modulate CB1 and PPARγ receptors and others markers associated with obesity
Published in Journal of functional foods (01-05-2019)“…[Display omitted] •Phytochemical characterization of ethanolic extract of the leaves from Mangifera indica.•Analyzes with extract of M. indica and its isolated…”
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Evaluation of the genotoxic potential of ethanolic extracts of stem bark and leaves of Bathysa cuspidata (A.St.-Hil.) Hook
Published in Revista de ciências farmacêuticas básica e aplicada (01-07-2012)“…Bathysa cuspidata (A.St.-Hil.) Hook. is a native tree of the Brazilian Atlantic Forest biome, widely used in Brazilian herbal medicine. Despite its widespread…”
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Antioxidant study indicative of antibacterial and antimutagenic activities of an ellagitannin-rich aqueous extract from the leaves of Miconia latecrenata
Published in Journal of ethnopharmacology (23-05-2019)“…Ethnopharmacological relevance; Several plant species of Miconia genus are commonly used in Brazilian folk medicine as anti-inflammatory agents and for the…”
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Antiplasmodial and cytotoxic effects of the methanol extract, canthinone alkaloids, squalene- and protolimonoid-type triterpenes from Homalolepis suffruticosa roots
Published in Journal of ethnopharmacology (01-03-2022)“…Different species of the Simaroubaceae family are used in traditional medicine to treat malaria. Among these is Homalolepis suffruticosa (syn. Simaba…”
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In Vitro and in Vivo Antimalarial Activity, Cytotoxicity and Phytochemical HRMS 2 Profile of Plants from the Western Pará State, Brazilian Amazonia
Published in Chemistry & biodiversity (01-01-2024)“…Ethnopharmacology and botanical taxonomy are valid criteria used to selecting plants for antimalarial bioprospection purposes. Based on these two criteria,…”
Get full text
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Identification of phenolic compounds and biologically related activities from Ocotea odorifera aqueous extract leaves
Published in Food chemistry (01-09-2017)“…•Antioxidant, antibacterial and antimutagenic activity of Ocotea odorifera leaves.•Rapid identification of bioactive flavonoids and tannins via…”
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Dereplication of Palicourea sessilis ethanol extracts by UPLC-DAD-ESI-MS/MS discloses the presence of hydroxycinnamic acid amides and the absence of monoterpene indole alkaloids
Published in Biochemical systematics and ecology (01-10-2020)“…Secondary metabolites characterization of ethanol extracts of Palicourea sessilis leaves and stems by UPLC-DAD-ESI-MS/MS led to putative identification of…”
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Assessment of the phenolic content, mutagenicity and genotoxicity of ethanolic extracts of stem bark and leaves from Strychnos pseudoquina A. St.-hil
Published in Drug and chemical toxicology (New York, N.Y. 1978) (02-09-2020)“…Strychnos pseudoquina is a plant species whose stem bark is used as bitter tonic beverage. The phytochemical analysis, as well as quantification of phenolic…”
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Phytochemical characterization and antioxidant, antibacterial and antimutagenic activities of aqueous extract from leaves of Alchornea glandulosa
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2018)“…Plant extracts exist as a complex matrix which serves as a source of numerous bioactive metabolites. The ultra performance liquid chromatography with…”
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Himatanthus bracteatus stem extracts present anti-flavivirus activity while an isolated sesquiterpene glucoside present only anti-Zika virus activity in vitro
Published in Natural product research (17-09-2021)“…The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus…”
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Antibacterial screening of plants from the Brazilian Atlantic Forest led to the identification of active compounds in Miconia latecrenata (DC.) Naudin
Published in Natural product research (04-08-2020)“…Antibiotic resistance is a serious global threat to public health. This has promoted the research for new drug targets, and the use of other approaches, such…”
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The mutagenic, DNA-damaging and antioxidative properties of bark and leaf extracts from Coutarea hexandra (Jacq.) K. Schum
Published in Environmental toxicology and pharmacology (01-03-2012)“…Highlights ► We investigated the mutagenic potential of chemically characterized extracts. ► In the mutagenic potential analysis were used Ames test and…”
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