Search Results - "Costa, Robert"

Chk2 Mediates Stabilization of the FoxM1 Transcription Factor To Stimulate Expression of DNA Repair Genes by Tan, Yongjun, Raychaudhuri, Pradip, Costa, Robert H.

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FoxM1 dances with mitosis by Costa, Robert H

“…The mammalian Forkhead Box M1 (FoxM1) protein, known for its function as a transcriptional regulator of G1/S progression, is also crucial for the G2/M…”
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FoxM1, a critical regulator of oxidative stress during oncogenesis by Park, Hyun Jung, Carr, Janai R, Wang, Zebin, Nogueira, Veronique, Hay, Nissim, Tyner, Angela L, Lau, Lester F, Costa, Robert H, Raychaudhuri, Pradip

“…The transcription factor FoxM1 is over‐expressed in most human malignancies. Although it is evident that FoxM1 has critical functions in tumour development and…”
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β-Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1 by ACKERMANN MISFELDT, Amanda, COSTA, Robert H, GANNON, Maureen

“…β-Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1 Amanda Ackermann Misfeldt 1 2 , Robert H…”
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Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase by Wang, I-Ching, Chen, Yi-Ju, Hughes, Douglas, Petrovic, Vladimir, Major, Michael L., Park, Hyung Jung, Tan, Yongjun, Ackerson, Timothy, Costa, Robert H.

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FoxM1 in Tumorigenicity of the Neuroblastoma Cells and Renewal of the Neural Progenitors by ZEBIN WANG, HYUN JUNG PARK, CARR, Janai R, CHEN, Yi-Ju, YU ZHENG, II, Jing, TYNER, Angela L, COSTA, Robert H, BAGCHI, Srilata, RAYCHAUDHURI, Pradip

“…Malignant neuroblastomas contain stem-like cells. These tumors also overexpress the Forkhead box transcription factor FoxM1. In this study, we investigated the…”
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Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1 by RADHAKRISHNAN, Senthil K, BHAT, Uppoor G, HUGHES, Douglas E, WANG, I-Ching, COSTA, Robert H, GARTEL, Andrei L

“…The oncogenic transcription factor forkhead box M1 (FoxM1) is overexpressed in a number of different carcinomas, whereas its expression is turned off in…”
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Anaphase-Promoting Complex/Cyclosome-Cdh1-Mediated Proteolysis of the Forkhead Box M1 Transcription Factor Is Critical for Regulated Entry into S Phase by Park, Hyun Jung, Costa, Robert H., Lau, Lester F., Tyner, Angela L., Raychaudhuri, Pradip

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Transcription factors in liver development, differentiation, and regeneration by Costa, Robert H., Kalinichenko, Vladimir V., Holterman, Ai‐Xuan L., Wang, Xinhe

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Forkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators by Major, Michael L., Lepe, Rita, Costa, Robert H.

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FoxM1 Regulates Transcription of JNK1 to Promote the G1/S Transition and Tumor Cell Invasiveness by Wang, I-Ching, Chen, Yi-Ju, Hughes, Douglas E., Ackerson, Timothy, Major, Michael L., Kalinichenko, Vladimir V., Costa, Robert H., Raychaudhuri, Pradip, Tyner, Angela L., Lau, Lester F.

“…The Forkhead box M1 (FoxM1) protein is a proliferation-specific transcription factor that plays a key role in controlling both the G1/S and G2/M transitions…”
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The forkhead box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer by KIM, Il-Man, ACKERSON, Timothy, KALINICHENKO, Vladimir V, RAMAKRISHNA, Sneha, TRETIAKOVA, Maria, WANG, I-Ching, KALIN, Tanya V, MAJOR, Michael L, GUSAROVA, Galina A, YODER, Helena M, COSTA, Robert H

“…The proliferation-specific Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident, Win, or MPP2) regulates expression of…”
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Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice by KALIN, Tanya V, WANG, I-Ching, ACKERSON, Timothy J, MAJOR, Michael L, DETRISAC, Carol J, KALINICHENKO, Vladimir V, LYUBIMOV, Alexander, COSTA, Robert H

“…The proliferation-specific Forkhead Box M1 (FoxM1 or FoxM1b) transcription factor is overexpressed in a number of aggressive human carcinomas. Mouse…”
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The Forkhead Box M1 Transcription Factor Contributes to the Development and Growth of Mouse Colorectal Cancer by Yoshida, Yuichi, Wang, I–Ching, Yoder, Helena M, Davidson, Nicholas O, Costa, Robert H

“…Background & Aims: In this study, we used Forkhead Box m1b (Foxm1b) transgenic mice and conditional Foxm1 knock-out mice to examine the role of Foxm1 in colon…”
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A Conserved Phosphorylation Site within the Forkhead Domain of FoxM1B Is Required for Its Activation by Cyclin-CDK1 by Chen, Yi-Ju, Dominguez-Brauer, Carmen, Wang, Zebin, Asara, John M., Costa, Robert H., Tyner, Angela L., Lau, Lester F., Raychaudhuri, Pradip

“…The Forkhead box M1 (FoxM1) transcription factor is critical for expression of the genes essential for G1/S transition and mitotic progression. To explore the…”
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The Forkhead Box m1b Transcription Factor Is Essential for Hepatocyte DNA Replication and Mitosis during Mouse Liver Regeneration by Wang, Xinhe, Kiyokawa, Hiroaki, Dennewitz, Margaret B., Costa, Robert H.

“…The Forkhead Box (Fox) proteins are an extensive family of transcription factors that shares homology in the winged helix DNA-binding domain and whose members…”
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A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment by Gusarova, Galina A, Wang, I-Ching, Major, Michael L, Kalinichenko, Vladimir V, Ackerson, Timothy, Petrovic, Vladimir, Costa, Robert H

“…The forkhead box m1 (Foxm1) transcription factor is essential for initiation of carcinogen-induced liver tumors; however, whether FoxM1 constitutes a…”
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Deregulation of FoxM1b leads to tumour metastasis by Park, Hyun Jung, Gusarova, Galina, Wang, Zebin, Carr, Janai R., Li, Jing, Kim, Ki‐Hyun, Qiu, Jin, Park, Yoon‐Dong, Williamson, Peter R., Hay, Nissim, Tyner, Angela L., Lau, Lester F., Costa, Robert H., Raychaudhuri, Pradip

“…The forkhead box M1b (FoxM1b) transcription factor is over‐expressed in human cancers, and its expression often correlates with poor prognosis. Previously,…”
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Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury by Zhao, You-Yang, Gao, Xiao-Pei, Zhao, Yidan D, Mirza, Muhammad K, Frey, Randall S, Kalinichenko, Vladimir V, Wang, I-Ching, Costa, Robert H, Malik, Asrar B

“…Recovery of endothelial integrity after vascular injury is vital for endothelial barrier function and vascular homeostasis. However, little is known about the…”
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The Forkhead Box M1 Transcription Factor Is Essential for Embryonic Development of Pulmonary Vasculature by Kim, Il-Man, Ramakrishna, Sneha, Gusarova, Galina A., Yoder, Helena M., Costa, Robert H., Kalinichenko, Vladimir V.

“…Transgenic and gene knock-out studies demonstrated that the mouse Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident,…”
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