Search Results - "Costa, Rafael"

DISA tool: Discriminative and informative subspace assessment with categorical and numerical outcomes by Alexandre, Leonardo, Costa, Rafael S, Henriques, Rui

“…Pattern discovery and subspace clustering play a central role in the biological domain, supporting for instance putative regulatory module discovery from omics…”
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Fermionic quantum gas at finite temperature within a Lorentz-violating background by Costa, Rafael L. J., Sobreiro, Rodrigo F.

“…Abstract In this work we consider a fermionic quantum gas within a Lorentz-violating background at finite temperature. We derive the effective action within…”
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One-loop Schwinger effect in the presence of Lorentz-violating background fields by Costa, Rafael L. J., Sobreiro, Rodrigo F.

“…In this work we make use of proper-time method to evaluate Schwinger effect in the presence of Lorentz-violating background fields. Specifically, we evaluate…”
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Pattern‐centric transformation of omics data grounded on discriminative gene associations aids predictive tasks in TCGA while ensuring interpretability by Patrício, André, Costa, Rafael S., Henriques, Rui

“…The increasing prevalence of omics data sources is pushing the study of regulatory mechanisms underlying complex diseases such as cancer. However, the vast…”
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Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor by Delgado‐Calle, Jesus, Tu, Xiaolin, Pacheco‐Costa, Rafael, McAndrews, Kevin, Edwards, Rachel, Pellegrini, Gretel G, Kuhlenschmidt, Kali, Olivos, Naomie, Robling, Alexander, Peacock, Munro, Plotkin, Lilian I, Bellido, Teresita

“…ABSTRACT Osteocytes integrate the responses of bone to mechanical and hormonal stimuli by poorly understood mechanisms. We report here that mice with…”
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Kinetic modeling of cell metabolism for microbial production by Costa, Rafael S., Hartmann, Andras, Vinga, Susana

“…•Computational kinetic models are essential for rational bioengineering applications.•We survey the available databases, standards and software tools that can…”
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DI2: prior-free and multi-item discretization of biological data and its applications by Alexandre, Leonardo, Costa, Rafael S, Henriques, Rui

“…Abstract Background A considerable number of data mining approaches for biomedical data analysis, including state-of-the-art associative models, require a form…”
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Enrichment analysis on regulatory subspaces: A novel direction for the superior description of cellular responses to SARS-CoV-2 by Rodrigues, Pedro, Costa, Rafael S., Henriques, Rui

“…Enrichment analysis of cell transcriptional responses to SARS-CoV-2 infection from biclustering solutions yields broader coverage and superior enrichment of GO…”
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Mixed-Mode Transmission Shapes Termite Gut Community Assemblies by da Costa, Rafael R., Poulsen, Michael

“…Understanding how microbial symbiont community assemblies are shaped over evolutionary time is challenging. The current state of the art involves exploring…”
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Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases by da Costa, Rafael M, Rodrigues, Daniel, Pereira, Camila A, Silva, Josiane F, Alves, Juliano V, Lobato, Núbia S, Tostes, Rita C

“…Free radicals act as secondary messengers, modulating a number of important biological processes, including gene expression, ion mobilization in transport…”
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SBML2HYB: a Python interface for SBML compatible hybrid modeling by Pinto, José, Costa, Rafael S, Alexandre, Leonardo, Ramos, João, Oliveira, Rui

“…Abstract Summary Here, we present sbml2hyb, an easy-to-use standalone Python tool that facilitates the conversion of existing mechanistic models of biological…”
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Predictability of COVID-19 Hospitalizations, Intensive Care Unit Admissions, and Respiratory Assistance in Portugal: Longitudinal Cohort Study by Patrício, André, Costa, Rafael S, Henriques, Rui

“…In the face of the current COVID-19 pandemic, the timely prediction of upcoming medical needs for infected individuals enables better and quicker care…”
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Melatonin prevents overproduction of reactive oxygen species and vascular dysfunction induced by cyclophosphamide by Pimenta, Gustavo F, Awata, Wanessa M C, Orlandin, Gabrielly G, Silva-Neto, Julio A, Assis, Victor O, da Costa, Rafael M, Bruder-Nascimento, Thiago, Tostes, Rita C, Tirapelli, Carlos R

“…Overproduction of reactive oxygen species (ROS) is a pathologic hallmark of cyclophosphamide toxicity. For this reason, antioxidant compounds emerge as…”
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Mining Pre-Surgical Patterns Able to Discriminate Post-Surgical Outcomes in the Oncological Domain by Alexandre, Leonardo, Costa, Rafael S., Santos, Lucio Lara, Henriques, Rui

“…Understanding the individualized risks of undertaking surgical procedures is essential to personalize preparatory, intervention and post-care protocols for…”
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Experts’ assessments of migration scenarios between the Middle East & North Africa and Europe by Boissonneault, Michaël, Costa, Rafael

“…We describe data collected among 138 migration experts about the repercussions of scenarios of social change on migration between the Middle East & North…”
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Symbiotic Plant Biomass Decomposition in Fungus-Growing Termites by da Costa, Rafael R, Hu, Haofu, Li, Hongjie, Poulsen, Michael

“…Termites are among the most successful animal groups, accomplishing nutrient acquisition through long-term associations and enzyme provisioning from microbial…”
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Perivascular Adipose Tissue as a Relevant Fat Depot for Cardiovascular Risk in Obesity by Costa, Rafael M, Neves, Karla B, Tostes, Rita C, Lobato, Núbia S

“…Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary…”
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On the challenges of predicting treatment response in Hodgkin's Lymphoma using transcriptomic data by Patrício, André, Costa, Rafael S, Henriques, Rui

“…Despite the advancements in multiagent chemotherapy in the past years, up to 10% of Hodgkin's Lymphoma (HL) cases are refractory to treatment and, after…”
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Aryl hydrocarbon receptor (AhR) activation contributes to high‐fat diet‐induced vascular dysfunction by Silva, Josiane Fernandes, Bolsoni, Juliana A., Costa, Rafael M., Alves, Juliano V., Bressan, Alecsander F. M., Silva, Luiz Eduardo V., Costa, Tiago J., Oliveira, Antonio E. R., Manzato, Carla P., Aguiar, Carlos A., Fazan, Rubens, Cunha, Fernando Q., Nakaya, Helder I., Carneiro, Fernando S., Tostes, Rita C.

“…Background and Purpose Metabolic and vascular dysfunction are common features of obesity. Aryl hydrocarbon receptor (AhR) regulates lipid metabolism and…”
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Current political uses of sport revised: beyond public diplomacy and sportswashing by Costa, Rafael, Moriconi, Marcelo

“…The successful emergence of the Gulf states as central players in the global sporting ecosystem has revived the intellectual debate on the political and…”
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