Search Results - "Costa, Pedro Augusto Carvalho"

The Robust and Modulated Biomarker Network Elicited by the Plasmodium vivax Infection Is Mainly Mediated by the IL-6/IL-10 Axis and Is Associated with the Parasite Load by Sadahiro, Aya, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Malheiro, Adriana, Nogueira, Paulo Afonso, Socorro Lopes dos Santos, Maria do Perpétuo, Monteiro Tarragô, Andréa, Garcia, Nadja Pinto, Paulo Diniz Pimentel, João, Augusto Carvalho Costa, Pedro, do Valle Antonelli, Lis Ribeiro, Guimarães da Costa, Allyson, Hekcmann, Maria Izabel Ovellar

“…Background. Recent studies have shown that the inflammatory process, including the biomarker production, and the intense activation of innate immune responses…”
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T follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection by Figueiredo, Maria Marta, Costa, Pedro Augusto Carvalho, Diniz, Suelen Queiroz, Henriques, Priscilla Miranda, Kano, Flora Satiko, Tada, Mauro Sugiro, Pereira, Dhelio Batista, Soares, Irene Silva, Martins-Filho, Olindo Assis, Jankovic, Dragana, Gazzinelli, Ricardo Tostes, Antonelli, Lis Ribeiro do Valle

“…Although the importance of humoral immunity to malaria has been established, factors that control antibody production are poorly understood. Follicular helper…”
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Plasmodium vivax Infection Alters Mitochondrial Metabolism in Human Monocytes by Diniz, Suelen Queiroz, Teixeira-Carvalho, Andréa, Figueiredo, Maria Marta, Costa, Pedro Augusto Carvalho, Rocha, Bruno Coelho, Martins-Filho, Olindo Assis, Gonçalves, Ricardo, Pereira, Dhélio Batista, Tada, Mauro Shugiro, Oliveira, Fabiano, Gazzinelli, Ricardo Tostes, Antonelli, Lis Ribeiro do Valle

“…Monocytes play an important role in the host defense against Plasmodium vivax as the main source of inflammatory cytokines and mitochondrial reactive oxygen…”
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Neutrophil paralysis in Plasmodium vivax malaria by Leoratti, Fabiana Maria de Souza, Trevelin, Silvia Cellone, Cunha, Fernando Queiroz, Rocha, Bruno Coelho, Costa, Pedro Augusto Carvalho, Gravina, Humberto Doriguêtto, Tada, Mauro Shugiro, Pereira, Dhelio Batista, Golenbock, Douglas Taylor, Antonelli, Lis Ribeiro do Valle, Gazzinelli, Ricardo T

“…The activation of innate immune responses by Plasmodium vivax results in activation of effector cells and an excessive production of pro-inflammatory cytokines…”
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Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: Submicroscopic parasitemic blood infects Nyssorhynchus darlingi by Almeida, Gregório Guilherme, Costa, Pedro Augusto Carvalho, Araujo, Maísa da Silva, Gomes, Gabriela Ribeiro, Carvalho, Alex Fiorini, Figueiredo, Maria Marta, Pereira, Dhelio Batista, Tada, Mauro Shugiro, Medeiros, Jansen Fernandes, Soares, Irene da Silva, Carvalho, Luzia Helena, Kano, Flora Satiko, Castro, Marcia Caldas de, Vinetz, Joseph Michael, Golenbock, Douglas Taylor, Antonelli, Lis Ribeiro do Valle, Gazzinelli, Ricardo Tostes

“…Individuals with asymptomatic infection due to Plasmodium vivax are posited to be important reservoirs of malaria transmission in endemic regions. Here we…”
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Dengue Patients with Early Hemorrhagic Manifestations Lose Coordinate Expression of the Anti-Inflammatory Cytokine IL-10 with the Inflammatory Cytokines IL-6 and IL-8 by Iani, Felipe Campos de Melo, Caldas, Sérgio, Duarte, Myrian Morato, Cury, Ana Luisa Furtado, Cecílio, Alzira Batista, Costa, Pedro Augusto Carvalho, Antonelli, Lis R, Gollob, Kenneth J

“…Dengue is responsible for a wide range of clinical manifestations, ranging from asymptomatic infections to severe cases. The alteration of cytokine levels…”
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Adenosine pathway regulates inflammation during Plasmodium vivax infection by Diniz, Suelen Queiroz, Figueiredo, Maria Marta, Costa, Pedro Augusto Carvalho, Martins-Filho, Olindo Assis, Teixeira-Carvalho, Andrea, Pereira, Dhélio Batista, Shugiro Tada, Mauro, Crocco Afonso, Luis Carlos, Kohlhoff, Markus, Zani, Carlos Leomar, Gazzinelli, Ricardo Tostes, Oliveira, Fabiano, Antonelli, Lis Ribeiro

“…spp. infection triggers the production of inflammatory cytokines that are essential for parasite control, and conversely responsible for symptoms of malaria…”
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Leishmania metacyclogenesis is promoted in the absence of purines by Serafim, Tiago Donatelli, Figueiredo, Amanda Braga, Costa, Pedro Augusto Carvalho, Marques-da-Silva, Eduardo Almeida, Gonçalves, Ricardo, de Moura, Sandra Aparecida Lima, Gontijo, Nelder Figueiredo, da Silva, Sydnei Magno, Michalick, Marilene Suzan Marques, Meyer-Fernandes, José Roberto, de Carvalho, Roberto Paes, Uliana, Silvia Reni Bortolin, Fietto, Juliana Lopes Rangel, Afonso, Luís Carlos Crocco

“…Leishmania parasites, the causative agent of leishmaniasis, are transmitted through the bite of an infected sand fly. Leishmania parasites present two basic…”
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Delivery of Plasmid DNA by lonizable Lipid Nanoparticles to Induce CAR Expression in T Cells by Prazeres, Pedro Henrique Dias Moura, Ferreira, Heloisa, Costa, Pedro Augusto Carvalho, da Silva, Walison, Alves, Marco Tullio, Padilla, Marshall, Thatte, Ajay, Santos, Anderson Kenedy, Lobo, Anderson Oliveira, Sabino, Adriano, Del Puerto, Helen Lima, Mitchell, Michael J, Guimaraes, Pedro Pires Goulart

“…Introduction: Chimeric antigen receptor (CAR) cell therapy represents a hallmark in cancer immunotherapy, with significant clinical results in the treatment of…”
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Essential role of the CCL2-CCR2 axis in Mayaro virus-induced disease by Santos, Franciele Martins, Costa, Victor Rodrigues de Melo, Araújo, Simone de, Sousa, Carla Daiane Ferreira de, Moreira, Thaiane Pinto, Gonçalves, Matheus Rodrigues, Santos, Anna Clara Paiva Menezes Dos, Ferreira, Heloísa Athayde Seabra, Costa, Pedro Augusto Carvalho, Barrioni, Breno Rocha, Bargi-Souza, Paula, Pereira, Marivalda de Magalhães, Nogueira, Maurício Lacerda, Souza, Danielle da Glória, Guimarães, Pedro Pires Goulart, Teixeira, Mauro Martins, Queiroz-Junior, Celso Martins, Costa, Vivian Vasconcelos

“…Mayaro virus (MAYV) is an emerging arbovirus member of the family and genus. MAYV infection causes an acute febrile illness accompanied by persistent…”
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Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models by Guimaraes, Lays Cordeiro, Costa, Pedro Augusto Carvalho, Scalzo Júnior, Sérgio Ricardo Aluotto, Ferreira, Heloísa Athaydes Seabra, Braga, Ana Carolina Soares, de Oliveira, Leonardo Camilo, Figueiredo, Maria Marta, Shepherd, Sarah, Hamilton, Alex, Queiroz-Junior, Celso Martins, da Silva, Walison Nunes, da Silva, Natália Jordana Alves, Rodrigues Alves, Marco Túllio, Santos, Anderson Kenedy, de Faria, Kevin Kelton Santos, Marim, Fernanda Martins, Fukumasu, Heidge, Birbrair, Alexander, Teixeira-Carvalho, Andréa, de Aguiar, Renato Santana, Mitchell, Michael J., Teixeira, Mauro Martins, Vasconcelos Costa, Vivian, Frezard, Frederic, Guimaraes, Pedro Pires Goulart

“…A safe and effective vaccine with long-term protection against SARS-CoV-2 variants of concern (VOCs) is a global health priority. Here, we develop lipid…”
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Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells by Prazeres, Pedro Henrique Dias Moura, Ferreira, Heloísa, Costa, Pedro Augusto Carvalho, da Silva, Walison, Alves, Marco Túllio, Padilla, Marshall, Thatte, Ajay, Santos, Anderson Kenedy, Lobo, Anderson Oliveira, Sabino, Adriano, Del Puerto, Helen Lima, Mitchell, Michael, Guimaraes, Pedro Pires Goulart

“…IntroductionChimeric antigen receptor (CAR) cell therapy represents a hallmark in cancer immunotherapy, with significant clinical results in the treatment of…”
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Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression by da Silva, Walison Nunes, Carvalho Costa, Pedro Augusto, Scalzo Júnior, Sérgio Ricardo Aluotto, Ferreira, Heloísa A S, Prazeres, Pedro Henrique Dias Moura, Campos, Caroline Leonel Vasconcelos, Rodrigues Alves, Marco Túllio, Alves da Silva, Natália Jordana, de Castro Santos, Ana Luiza, Guimarães, Lays Cordeiro, Chen Ferris, Maria Eduarda, Thatte, Ajay, Hamilton, Alex, Bicalho, Kelly Alves, Lobo, Anderson Oliveira, Santiago, Helton da Costa, da Silva Barcelos, Lucíola, Figueiredo, Maria Marta, Teixeira, Mauro Martins, Vasconcelos Costa, Vivian, Mitchell, Michael J, Frézard, Frédéric, Pires Goulart Guimaraes, Pedro

“…Immunotherapy has revolutionized cancer treatment by harnessing the immune system to enhance antitumor responses while minimizing off-target effects. Among the…”
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Vacinas: amigas ou inimigas? by Costa, Pedro Augusto Carvalho, Rocha, Bruno Coelho, Birbrair, Alexander

“…In this issue the teacher Pedro Augusto Carvalho Costa along with collaborators Bruno Coelho Rocha and Alexander Bribair wrote a letter on the subject of…”
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Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: Submicroscopic parasitemic blood infects Nyssorhynchus darlingi by Gregório Guilherme Almeida, Pedro Augusto Carvalho Costa, Maísa da Silva Araujo, Gabriela Ribeiro Gomes, Alex Fiorini Carvalho, Maria Marta Figueiredo, Dhelio Batista Pereira, Mauro Shugiro Tada, Jansen Fernandes Medeiros, Irene da Silva Soares, Luzia Helena Carvalho, Flora Satiko Kano, Marcia Caldas de Castro, Joseph Michael Vinetz, Douglas Taylor Golenbock, Lis Ribeiro do Valle Antonelli, Ricardo Tostes Gazzinelli

“…Individuals with asymptomatic infection due to Plasmodium vivax are posited to be important reservoirs of malaria transmission in endemic regions. Here we…”
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siRNA lipid nanoparticles for CXCL12 silencing modulate brain immune response during Zika infection by Costa, Pedro Augusto Carvalho, da Silva, Walison Nunes, Moura Prazeres, Pedro Henrique Dias, Ferreira, Heloísa Athaydes Seabra, da Silva, Natália Jordana Alves, Figueiredo, Maria Marta, da Silva Oliveira, Bruna, Scalzo Júnior, Sérgio Ricardo Aluotto, Silva Santos, Felipe Rocha da, Fernandes, Rúbia Aparecida, Palanki, Rohan, Hamilton, Alex G., Birbrair, Alexander, Santos, Victor Rodrigues, de Miranda, Aline Silva, Mitchell, Michael J., Teixeira, Mauro Martins, Costa, Vivian Vasconcelos, Guimarães, Pedro Pires Goulart

“…CXCL12 is a key chemokine implicated in neuroinflammation, particularly during Zika virus (ZIKV) infection. Specifically, CXCL12 is upregulated in circulating…”
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Oral formulation of Wnt inhibitor complex reduces inflammation and fibrosis in intraperitoneal implants in vivo by de Castro Santos, Ana Luíza, da Silva, Natália Jordana Alves, Viana, Celso Tarso Rodrigues, dos Santos, Letícia Cristine Cardoso, da Silva, Gabriel Henrique Costa, Scalzo Júnior, Sérgio Ricardo Aluotto, Costa, Pedro Augusto Carvalho, da Silva, Walison Nunes, de Jesus, Itamar Couto Guedes, Birbrair, Alexander, de Magalhães, Mariana T. Q., Frézard, Frédéric, Guatimosim, Silvia, Haley, Rebecca M., Mitchell, Michael J., Andrade, Silvia Passos, Campos, Paula Peixoto, Guimaraes, Pedro Pires Goulart

“…The use of implantable biomaterials to replace physiological and anatomical functions has been widely investigated in the clinic. However, the selection of…”
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