Search Results - "Costa, Nikola"

Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage by Requejo, Raquel, Hurd, Thomas R, Costa, Nikola J, Murphy, Michael P

“…Cysteine plays a number of important roles in protecting the cell from oxidative damage through its thiol functional group. These defensive functions are…”
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Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE by Beer, Samantha M, Taylor, Ellen R, Brown, Stephanie E, Dahm, Christina C, Costa, Nikola J, Runswick, Michael J, Murphy, Michael P

“…The redox poise of the mitochondrial glutathione pool is central in the response of mitochondria to oxidative damage and redox signaling, but the mechanisms…”
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Glutathionylation of mitochondrial proteins by Hurd, Thomas R, Costa, Nikola J, Dahm, Christina C, Beer, Samantha M, Brown, Stephanie E, Filipovska, Aleksandra, Murphy, Michael P

“…Many proteins contain free thiols that can be modified by the reversible formation of mixed disulfides with low-molecular-weight thiols through a process…”
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A Single-Center, Observational Study of 607 Children and Young People Presenting With Differences of Sex Development (DSD) by Man, Elim, Mushtaq, Imran, Barnicoat, Angela, Carmichael, Polly, Hughes, Claire R, Davies, Kate, Aitkenhead, Helen, Amin, Rakesh, Buchanan, Charles R, Cherian, Abraham, Costa, Nikola J, Creighton, Sarah M, Duffy, Patrick G, Hewson, Emma, Hindmarsh, Peter C, Monzani, Louisa C, Peters, Catherine J, Ransley, Philip G, Smeulders, Naima, Spoudeas, Helen A, Wood, Dan, Hughes, Ieuan A, Katugampola, Harshini, Brain, Caroline E, Dattani, Mehul T, Achermann, John C

“…Context: Differences of sex development (DSD) represent a wide range of conditions presenting at different ages to various health professionals. Establishing a…”
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Interactions of mitochondrial thiols with nitric oxide by Costa, Nikola J, Dahm, Christina C, Hurrell, Fiona, Taylor, Ellen R, Murphy, Michael P

“…The interaction of nitric oxide (NO) with mitochondria is of pathological significance and is also a potential mechanism for the regulation of mitochondrial…”
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Normal 25-Hydroxyvitamin D Levels Are Associated with Less Proteinuria and Attenuate Renal Failure Progression in Children with CKD by Shroff, Rukshana, Aitkenhead, Helen, Costa, Nikola, Trivelli, Antonella, Litwin, Mieczyslaw, Picca, Stefano, Anarat, Ali, Sallay, Peter, Ozaltin, Fatih, Zurowska, Aleksandra, Jankauskiene, Augustina, Montini, Giovanni, Charbit, Marina, Schaefer, Franz, Wühl, Elke

“…Angiotensin-converting enzyme inhibitors (ACEi) for renin-angiotensin-aldosterone system (RAAS) blockade are routinely used to slow CKD progression. However,…”
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Glutaredoxin 2 Catalyzes the Reversible Oxidation and Glutathionylation of Mitochondrial Membrane Thiol Proteins by Beer, Samantha M., Taylor, Ellen R., Brown, Stephanie E., Dahm, Christina C., Costa, Nikola J., Runswick, Michael J., Murphy, Michael P.

“…The redox poise of the mitochondrial glutathione pool is central in the response of mitochondria to oxidative damage and redox signaling, but the mechanisms…”
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Factors regulating circulating vascular endothelial growth factor (VEGF): Association with bone mineral density (BMD) in post-menopausal osteoporosis by Costa, Nikola, Paramanathan, Sophia, Donald, Dorothy Mac, Wierzbicki, Anthony S., Hampson, Geeta

“…Vascular endothelial growth factor (VEGF) plays an important role in bone health. We investigated the factors which influence circulating VEGF and their…”
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