Search Results - "Costa, Natália R"
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A viral map of gastrointestinal cancers
Published in Life sciences (1973) (15-04-2018)“…Cancers of the gastrointestinal tract (GIT) are expected to account for approximately 20% of all cancers in 2017. Apart from their high incidence, GIT cancers…”
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The Role of MicroRNAs in the Metastatic Process of High-Risk HPV-Induced Cancers
Published in Cancers (05-12-2018)“…High-risk human papillomavirus (HPV)-driven cancers represent a major health concern worldwide. Despite the constant effort to develop and promote vaccination…”
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Impact of MUC1 mucin downregulation in the phenotypic characteristics of MKN45 gastric carcinoma cell line
Published in PloS one (02-11-2011)“…Gastric carcinoma is the second leading cause of cancer-associated death worldwide. The high mortality associated with this disease is in part due to limited…”
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Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer
Published in Oncotarget (01-10-2013)“…Histone variants seem to play a major role in gene expression regulation. In prostate cancer, H2A.Z and its acetylated form are implicated in oncogenes'…”
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Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential
Published in Journal of cellular and molecular medicine (01-11-2014)“…Epigenetic alterations are common in prostate cancer (PCa) and seem to contribute decisively to its initiation and progression. Moreover, aberrant promoter…”
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Expression of LncRNAs in HPV-induced Carcinogenesis and Cancer Cachexia: A Study in K14-HPV16 Mice
Published in Anticancer research (01-05-2022)“…To evaluate the expression of lincRNA-p21, H19, EMX2OS, SNHG12 and MALAT1 in a mouse model of human papillomavirus 16 (HPV16)-induced carcinogenesis and…”
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Differential Incidence of Tongue Base Cancer in Male and Female HPV16-Transgenic Mice: Role of Female Sex Hormone Receptors
Published in Pathogens (Basel) (22-09-2021)“…A growing proportion of oropharyngeal squamous cell carcinomas (OPSCC) are associated with infection by high-risk human papillomavirus (HPV). For reasons that…”
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Laboratory diagnosis of chronic kidney disease in adults: an overview of hospitals inserted in the Portuguese National Health System
Published in Jornal brasileiro de patologia e medicina laboratorial (01-11-2017)“…ABSTRACT Introduction: The laboratory diagnosis of chronic kidney disease (CKD) is a simple and cost-effective procedure that allows the detection of early…”
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Phenotypic impact of deregulated expression of class I histone deacetylases in urothelial cell carcinoma of the bladder
Published in Molecular carcinogenesis (01-07-2015)“…ABSTRACT Deregulated expression of histone deacetylases (HDACs) has been implicated in tumorigenesis. Herein, we investigated class I HDACs expression in…”
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Epigenetic regulation of EFEMP 1 in prostate cancer: biological relevance and clinical potential
Published in Journal of cellular and molecular medicine (01-11-2014)“…Epigenetic alterations are common in prostate cancer ( PC a) and seem to contribute decisively to its initiation and progression. Moreover, aberrant promoter…”
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Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells
Published in World journal of gastroenterology : WJG (07-03-2008)“…AIM:To evaluate the influence of MUC1 mucin variable number of tandem repeats (VNTR) variability on H pylori adhesion to gastric cells. METHODS: Enzyme linked…”
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Role of soluble guanylate cyclase activation in the gastroprotective effect of the HO-1/CO pathway against alendronate-induced gastric damage in rats
Published in European journal of pharmacology (30-01-2013)“…Our objective was to evaluate the role of soluble guanylate cyclase (sGC) activation in the gastroprotective effect of the HO-1/CO pathway against…”
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