Search Results - "Costa, L.G."

Polyphenols and health: What compounds are involved? by Del Rio, D, Costa, L.G, Lean, M.E.J, Crozier, A

“…Abstract On the basis of prospective, cross-sectional and intervention studies linking polyphenols to human health, several experimental papers in the…”
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Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression by Giordano, G., Tait, L., Furlong, C.E., Cole, T.B., Kavanagh, T.J., Costa, L.G.

“…Paraoxonase 2 (PON2), a member of a gene family that also includes PON1 and PON3, is expressed in most tissues, including the brain. In mouse brain, PON2…”
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Differential expression of cysteine peptidase genes in the inner integument and endosperm of developing seeds of Jatropha curcas L. (Euphorbiaceae) by Rocha, Antônio J., Soares, Emanoella L., Costa, José H., Costa, Washington L.G., Soares, Arlete A., Nogueira, Fábio C.S., Domont, Gilberto B., Campos, Francisco A.P.

“…•Two genes for KDEL-CysEPs and three genes for VPEs are present in the J. curcas genome.•The KDEL-CysEP and VPE genes were expressed mainly from Stage IV in…”
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Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases by Giordano, G., Klintworth, H.M., Kavanagh, T.J., Costa, L.G.

“…In mouse cerebellar granule neurons (CGNs) the marine neurotoxin domoic acid (DomA) induces neuronal cell death, either by apoptosis or by necrosis, depending…”
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Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells by Giordano, Gennaro, Li, Li, White, Collin C, Farin, Fred M, Wilkerson, Hui W, Kavanagh, Terrance J, Costa, L.G

“…In mouse cerebellar granule neurons (CGNs) low concentrations of domoic acid (DomA) induce apoptotic cell death, which is mediated by oxidative stress;…”
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Effects of paraoxonase-1 (PON1) status on pre- and postnatal exposures to chlorpyrifos oxon and diazoxon by Furlong, C.E, Li, W.-F, Cole, T.B, Beyer, R.P, Bammler, T.K, S.S., Park, Farin, F.M, Costa, L.G

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The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism by Costa, L.G., Li, W.F., Richter, R.J., Shih, D.M., Lusis, A., Furlong, C.E.

“…In human populations, serum paraoxonase (PON1) exhibits a substrate dependent polymorphism. The Arg192 isoform hydrolyzes paraoxon rapidly but diazoxon, soman…”
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Role of autophagy in environmental neurotoxicity by Pellacani, C., Costa, L.G.

“…Human exposure to neurotoxic pollutants (e.g. metals, pesticides and other chemicals) is recognized as a key risk factor in the pathogenesis of…”
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Determination of hemoglobin adducts in humans occupationally exposed to acrylamide by Bergmark, E, Calleman, C J, He, F, Costa, L G

“…Hemoglobin (Hb) adduct determinations were used to monitor occupational exposure to acrylamide (AA) and acrylonitrile (AN). Forty-one workers in a factory in…”
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Relationships between biomarkers of exposure and neurological effects in a group of workers exposed to acrylamide by Calleman, C J, Wu, Y, He, F, Tian, G, Bergmark, E, Zhang, S, Deng, H, Wang, Y, Crofton, K M, Fennell, T

“…A study was performed among 41 workers heavily exposed to a mixture of acrylamide and acrylonitrile in the city of Xinxiang, Henan province, People's Republic…”
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Integrated transcriptome and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during gestation and lactation by Aquino, A.M., Alonso-Costa, L.G., Santos, S.A.A., Rocha, V.A., Barbisan, L.F., Bedrat, A., Justulin, L.A., Flaws, J.A., Lemos, B., Scarano, W.R.

“…As the second leading cause of death for cancer among men worldwide, prostate cancer (PCa) prevention and detection remain a critical challenge. One aspect of…”
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Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification by Furlong, C E, Costa, L G, Hassett, C, Richter, R J, Sundstrom, J A, Adler, D A, Disteche, C M, Omiecinski, C J, Chapline, C, Crabb, J W

“…Human and rabbit paraoxonases/arylesterases were purified to homogeneity by chromatographic and gel electrophoretic/isofocusing procedures coupled with…”
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Synergistic interactions between PBDEs and PCBs in human neuroblastoma cells by Pellacani, C, Tagliaferri, S, Caglieri, A, Goldoni, M, Giordano, G, Mutti, A, Costa, L. G

“…Polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) are ubiquitous environmental pollutants. Exposure to these chemicals has been…”
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Human PON1, a biomarker of risk of disease and exposure by Furlong, C.E., Suzuki, S.M., Stevens, R.C., Marsillach, J., Richter, R.J., Jarvik, G.P., Checkoway, H., Samii, A., Costa, L.G., Griffith, A., Roberts, J.W., Yearout, D., Zabetian, C.P.

“…Human paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated serum enzyme that exhibits a broad substrate specificity. In addition to protecting…”
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Contaminants in fish: Risk–benefit considerations by Costa, L.G., Manzo, L.

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A comparison of the antinociceptive responses to the GABA-receptor agonists THIP and baclofen by Vaught, J L, Pelley, K, Costa, L G, Setler, P, Enna, S J

“…The antinociceptive action of the gamma-aminobutyric acid (GABA) agonists THIP and baclofen was evaluated in mice using hot-plate (48 and 55 degrees C) and…”
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Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors by Guizzetti, M., Moore, N.H., Giordano, G., Costa, L.G.

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Is the Montreal Cognitive Assessment (MoCA) screening superior to the Mini-Mental State Examination (MMSE) in the detection of mild cognitive impairment (MCI) and Alzheimer's Disease (AD) in the elderly? by Pinto, Tiago C C, Machado, Leonardo, Bulgacov, Tatiana M, Rodrigues-Júnior, Antônio L, Costa, Maria L G, Ximenes, Rosana C C, Sougey, Everton B

“…ABSTRACTObjective:To compare the accuracy of Mini-Mental State Examination (MMSE) and of the Montreal Cognitive Assessment (MoCA) in tracking mild cognitive…”
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Genetic variability factors in human susceptibility to organophosphorus compounds by Furlong, C.E., Cole, T.B., Jansen, K.L., Richter, R.J., Bammler, T.K., Beyer, R.P., Farin, F., Costa, L.G.

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Evaluation of in vitro neurotoxicity of methyl mercury, PCB153 and PCB126 by Vitalone, A., Giordano, G., Costa, L.G.

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