Search Results - "Costa, Katrina"
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A novel dual-plasmid platform provides scalable transfection yielding improved productivity and packaging across multiple AAV serotypes and genomes
Published in Molecular therapy. Methods & clinical development (08-06-2023)“…Transient transfection of mammalian cells using plasmid DNA is a standard method to produce adeno-associated virus (AAV) vectors allowing for flexible and…”
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Abstract 290: Development and characterization of antibodies specific for the SS18-SSX fusion protein in synovial sarcoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Synovial sarcoma (SS) is a soft tissue cancer characterized by the fusion of the SS18 gene, which encodes for a subunit of the BAF ATP-dependent…”
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An Improved Helper Plasmid Containing Deletions Within the E4 and E2a Genes Results in Increased Adeno-Associated Virus Productivity
Published in Human gene therapy (01-09-2024)“…The use of a helper plasmid to replace adenovirus infection for adeno-associated virus (AAV) manufacturing has been common practice for decades. Adenovirus E4,…”
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