Search Results - "Costa, Fabio T."

Keras R-CNN: library for cell detection in biological images using deep neural networks by Hung, Jane, Goodman, Allen, Ravel, Deepali, Lopes, Stefanie C P, Rangel, Gabriel W, Nery, Odailton A, Malleret, Benoit, Nosten, Francois, Lacerda, Marcus V G, Ferreira, Marcelo U, Rénia, Laurent, Duraisingh, Manoj T, Costa, Fabio T M, Marti, Matthias, Carpenter, Anne E

“…A common yet still manual task in basic biology research, high-throughput drug screening and digital pathology is identifying the number, location, and type of…”
Get full text

Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes by Malleret, Benoît, Xu, Fenggao, Mohandas, Narla, Suwanarusk, Rossarin, Chu, Cindy, Leite, Juliana A, Low, Kayen, Turner, Claudia, Sriprawat, Kanlaya, Zhang, Rou, Bertrand, Olivier, Colin, Yves, Costa, Fabio T M, Ong, Choon Nam, Ng, Mah Lee, Lim, Chwee Teck, Nosten, Francois, Rénia, Laurent, Russell, Bruce

“…The transition from enucleated reticulocytes to mature normocytes is marked by substantial remodeling of the erythrocytic cytoplasm and membrane. Despite…”
Get full text

Deep Learning-driven research for drug discovery: Tackling Malaria by Neves, Bruno J, Braga, Rodolpho C, Alves, Vinicius M, Lima, Marília N N, Cassiano, Gustavo C, Muratov, Eugene N, Costa, Fabio T M, Andrade, Carolina Horta

“…Malaria is an infectious disease that affects over 216 million people worldwide, killing over 445,000 patients annually. Due to the constant emergence of…”
Get full text

A suitable RNA preparation methodology for whole transcriptome shotgun sequencing harvested from Plasmodium vivax-infected patients by Bourgard, Catarina, Lopes, Stefanie C. P., Lacerda, Marcus V. G., Albrecht, Letusa, Costa, Fabio T. M.

“…Plasmodium vivax is a world-threatening human malaria parasite, whose biology remains elusive. The unavailability of in vitro culture, and the difficulties in…”
Get full text

Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons by Bilsland, Elizabeth, Tavella, Tatyana A, Krogh, Renata, Stokes, Jamie E, Roberts, Annabelle, Ajioka, James, Spring, David R, Andricopulo, Adriano D, Costa, Fabio T M, Oliver, Stephen G

“…Violacein is a deep violet compound that is produced by a number of bacterial species. It is synthesized from tryptophan by a pathway that involves the…”
Get full text

On the Cytoadhesion of Plasmodium vivax–Infected Erythrocytes by Carvalho, Bruna O., Lopes, Stefanie C. P., Nogueira, Paulo A., Orlandi, Patricia P., Bargieri, Daniel Y., Blanco, Yara C., Mamoni, Ronei, Leite, Juliana A., Rodrigues, Mauricio M., Soares, Irene S., Oliveira, Tatiane R., Wunderlich, Gerhard, Lacerda, Marcus V. G., del Portillo, Hernando A., Araújo, Maria O. G., Russell, Bruce, Suwanarusk, Rossarin, Snounou, Georges, Rénia, Laurent, Costa, Fabio T. M.

“…Background. Plasmodium falciparum and Plasmodium vivax are responsible for most of the global burden of malaria. Although the accentuated pathogenicity of P…”
Get full text

Violacein Extracted from Chromobacterium violaceum Inhibits Plasmodium Growth In Vitro and In Vivo by LOPES, Stefanie C. P, BLANCO, Yara C, COSTA, Fabio T. M, JUSTO, Giselle Z, NOGUEIRA, Paulo A, RODRIGUES, Francisco L. S, GOELNITZ, Uta, WUNDERLICH, Gerhard, FACCHINI, Gustavo, BROCCHI, Marcelo, DURAN, Nelson

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Paucity of Plasmodium vivax Mature Schizonts in Peripheral Blood Is Associated With Their Increased Cytoadhesive Potential by Lopes, Stefanie C. P., Albrecht, Letusa, Carvalho, Bruna O., Siqueira, André M., Thomson-Luque, Richard, Nogueira, Paulo A., Fernandez-Becerra, Carmen, del Portillo, Hernando A., Russell, Bruce M., Rénia, Laurent, Lacerda, Marcus V. G., Costa, Fabio T. M.

“…There is now a growing body of evidence that challenges the current view that Plasmodium vivax-infected erythrocyte (Pv-iE) are unable to sequester. Here we…”
Get full text

Human ex vivo studies on asexual Plasmodium vivax: The best way forward by Russell, Bruce, Suwanarusk, Rossarin, Malleret, Benoit, Costa, Fabio T.M., Snounou, Georges, Kevin Baird, J., Nosten, François, Rénia, Laurent

“…[Display omitted] ► Plasmodium vivax studies have been hampered by the lack of continuous blood stage culture. ► New or improved ex vivo methods have been…”
Get full text

Rheopathologic Consequence of Plasmodium vivax Rosette Formation by Zhang, Rou, Lee, Wenn-Chyau, Lau, Yee-Ling, Albrecht, Letusa, Lopes, Stefanie C P, Costa, Fabio T M, Suwanarusk, Rossarin, Nosten, Francois, Cooke, Brian M, Rénia, Laurent, Russell, Bruce

“…Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the case of Plasmodium vivax, the parasite rapidly decreases…”
Get full text

Vaccination with Live Plasmodium yoelii Blood Stage Parasites under Chloroquine Cover Induces Cross-Stage Immunity against Malaria Liver Stage by Belnoue, Elodie, Voza, Tatiana, Costa, Fabio T. M, Gruner, Anne Charlotte, Mauduit, Marjorie, Rosa, Daniela Santoro, Depinay, Nadya, Kayibanda, Michele, Vigario, Ana Margarida, Mazier, Dominique, Snounou, Georges, Sinnis, Photini, Renia, Laurent

“…Immunity to malaria has long been thought to be stage-specific. In this study we show that immunization of BALB/c mice with live erythrocytes infected with…”
Get full text

A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax by Russell, Bruce, Suwanarusk, Rossarin, Borlon, Céline, Costa, Fabio T.M., Chu, Cindy S., Rijken, Marcus J., Sriprawat, Kanlaya, Warter, Lucile, Koh, Esther G.L., Malleret, Benoit, Colin, Yves, Bertrand, Olivier, Adams, John H., D'Alessandro, Umberto, Snounou, Georges, Nosten, Francois, Rénia, Laurent

“…Currently, there are no reliable RBC invasion assays to guide the discovery of vaccines against Plasmodium vivax, the most prevalent malaria parasite in Asia…”
Get full text

New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin by Bargieri, Daniel Y, Rosa, Daniela S, Braga, Catarina J.M, Carvalho, Bruna O, Costa, Fabio T.M, Espíndola, Noeli Maria, Vaz, Adelaide José, Soares, Irene S, Ferreira, Luis C.S, Rodrigues, Mauricio M

“…Abstract The present study evaluated the immunogenicity of new malaria vaccine formulations based on the 19 kDa C-terminal fragment of Plasmodium vivax…”
Get full text

Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics by Bourgard, Catarina, Albrecht, Letusa, Kayano, Ana C A V, Sunnerhagen, Per, Costa, Fabio T M

“…During the last decade, the vast omics field has revolutionized biological research, especially the genomics, transcriptomics and proteomics branches, as…”
Get full text

On the pathogenesis of Plasmodium vivax malaria: Perspectives from the Brazilian field by Costa, Fabio T.M., Lopes, Stefanie C.P., Albrecht, Letusa, Ataíde, Ricardo, Siqueira, André M., Souza, Rodrigo M., Russell, Bruce, Renia, Laurent, Marinho, Claudio R.F., Lacerda, Marcus V.G.

“…[Display omitted] ► The main and recent findings on severe vivax malaria in Brazil are pointed out. ► The Brazilian infrastructure for vivax malaria research…”
Get full text

Protective T Cell Immunity against Malaria Liver Stage after Vaccination with Live Sporozoites under Chloroquine Treatment by Belnoue, Elodie, Costa, Fabio T. M, Frankenberg, Tobias, Vigario, Ana Margarida, Voza, Tatiana, Leroy, Nicolas, Rodrigues, Mauricio M, Landau, Irene, Snounou, Georges, Renia, Laurent

“…In this study we present the first systematic analysis of the immunity induced by normal Plasmodium yoelii sporozoites in mice. Immunization with sporozoites,…”
Get full text

Fucosylated Chondroitin Sulfate Inhibits Plasmodium falciparum Cytoadhesion and Merozoite Invasion by BASTOS, Marcele F, ALBRECHT, Letusa, FERREIRA, Marcelo U, MARINHO, Claudio R. F, MOURAO, Paulo A. S, PAVAO, Mauro S. G, COSTA, Fabio T. M, KOZLOWSKI, Eliene O, LOPES, Stefanie C. P, BLANCO, Yara C, CARLOS, Bianca C, CASTINEIRAS, Catarina, VICENTE, Cristina P, WERNECK, Claudio C, WUNDERLICH, Gerhard

“…Sequestration of Plasmodium falciparum-infected erythrocytes (Pf-iEs) in the microvasculature of vital organs plays a key role in the pathogenesis of…”
Get full text

In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate by Cravo, Pedro, Machado, Renato B, Leite, Juliana A, Leda, Taizy, Suwanarusk, Rossarin, Bittencourt, Najara, Albrecht, Letusa, Judice, Carla, Lopes, Stefanie C P, Lacerda, Marcus V G, Ferreira, Marcelo U, Soares, Irene S, Goh, Yun Shan, Bargieri, Daniel Y, Nosten, François, Russell, Bruce, Rénia, Laurent, Costa, Fabio T M

“…Technical limitations for culturing the human malaria parasite Plasmodium vivax have impaired the discovery of vaccine candidates, challenging the malaria…”
Get full text

Purification Methodology for Viable and Infective Plasmodium vivax Gametocytes That Is Compatible with Transmission-Blocking Assays by Vera, Omaira, Brelas de Brito, Paula, Albrecht, Letusa, Martins-Campos, Keillen Monick, Pimenta, Paulo F P, Monteiro, Wuelton M, Lacerda, Marcus V G, Lopes, Stefanie C P, Costa, Fabio T M

“…Significant progress toward the control of malaria has been achieved, especially regarding Plasmodium falciparum infections. However, the unique biology of…”
Get full text

Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis by Farias, Alessandro S, Talaisys, Rafael L, Blanco, Yara C, Lopes, Stefanie C P, Longhini, Ana Leda F, Pradella, Fernando, Santos, Leonilda M B, Costa, Fabio T M

“…Experimental autoimmune encephalomyelitis (EAE) is used as an animal model for human multiple sclerosis (MS), which is an inflammatory demyelinating autoimmune…”
Get full text