Search Results - "Costa, B A"

Targeting replication stress in cancer therapy by da Costa, Alexandre André B. A., Chowdhury, Dipanjan, Shapiro, Geoffrey I., D’Andrea, Alan D., Konstantinopoulos, Panagiotis A.

“…Replication stress is a major cause of genomic instability and a crucial vulnerability of cancer cells. This vulnerability can be therapeutically targeted by…”
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Is a verification phase useful for confirming maximal oxygen uptake in apparently healthy adults? A systematic review and meta-analysis by Costa, Victor A B, Midgley, Adrian W, Carroll, Sean, Astorino, Todd A, de Paula, Tainah, Farinatti, Paulo, Cunha, Felipe A

“…The 'verification phase' has emerged as a supplementary procedure to traditional maximal oxygen uptake (VO2max) criteria to confirm that the highest possible…”
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Genomic profiling in ovarian cancer retreated with platinum based chemotherapy presented homologous recombination deficiency and copy number imbalances of CCNE1 and RB1 genes by da Costa, Alexandre A B A, do Canto, Luisa M, Larsen, Simon Jonas, Ribeiro, Adriana Regina Gonçalves, Stecca, Carlos Eduardo, Petersen, Annabeth Høgh, Aagaard, Mads M, de Brot, Louise, Baumbach, Jan, Baiocchi, Glauco, Achatz, Maria Isabel, Rogatto, Silvia Regina

“…Ovarian carcinomas presenting homologous recombination deficiency (HRD), which is observed in about 50% of cases, are more sensitive to platinum and PARP…”
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A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer by Konstantinopoulos, Panagiotis A., da Costa, Alexandre André B. A., Gulhan, Doga, Lee, Elizabeth K., Cheng, Su-Chun, Hendrickson, Andrea E. Wahner, Kochupurakkal, Bose, Kolin, David L., Kohn, Elise C., Liu, Joyce F., Stover, Elizabeth H., Curtis, Jennifer, Tayob, Nabihah, Polak, Madeline, Chowdhury, Dipanjan, Matulonis, Ursula A., Färkkilä, Anniina, D’Andrea, Alan D., Shapiro, Geoffrey I.

“…In a trial of patients with high grade serous ovarian cancer (HGSOC), addition of the ATR inhibitor berzosertib to gemcitabine improved progression free…”
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Confirming the attainment of maximal oxygen uptake within special and clinical groups: A systematic review and meta-analysis of cardiopulmonary exercise test and verification phase protocols by Costa, Victor A B, Midgley, Adrian W, Baumgart, Julia K, Carroll, Sean, Astorino, Todd A, Schaun, Gustavo Z, Fonseca, Guilherme F, Cunha, Felipe A

“…A plateau in oxygen uptake ([Formula: see text]) during an incremental cardiopulmonary exercise test (CPET) to volitional exhaustion appears less likely to…”
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Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil by Cotrim, Deborah Porto, Ribeiro, Adriana Regina Gonçalves, Paixão, Daniele, de Queiroz Soares, Diogo Cordeiro, Jbili, Rima, Pandolfi, Natasha Carvalho, Cezana, Camila, de Cássia Mauro, Carine, Mantoan, Henrique, Bovolim, Graziele, de Brot, Louise, Torrezan, Giovana Tardin, Carraro, Dirce Maria, Baiocchi, Glauco, da Cruz Formiga, Maria Nirvana, da Costa, Alexandre A B A

“…BRCA1/2 pathogenic (P) and likely pathogenic (LP) germline variants are frequent among patients with ovarian carcinoma. However, these variants have not been…”
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Neoadjuvant Chemotherapy Followed by Interval Debulking Surgery and the Risk of Platinum Resistance in Epithelial Ovarian Cancer by da Costa, Alexandre A. B. A., Valadares, Camila V., Baiocchi, Glauco, Mantoan, Henrique, Saito, Augusto, Sanches, Solange, Guimarães, Andréia P., Achatz, Maria Isabel W.

“…Background Interval debulking surgery (IDS) is an option for treating patients with advanced ovarian carcinoma. Two randomized trials have shown similar…”
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Pathological factors associated with non‐sentinel lymph node metastasis in early stage cervical cancer by Diniz, Thiago P., Faloppa, Carlos C., Mantoan, Henrique, Gonçalves, Bruna T., Kumagai, Lillian Y., Menezes, Ademir N. O., Badiglian‐Filho, Levon, Guimaraes, Andrea P. G., Costa, Alexandre A. B. A., De Brot, Louise, Baiocchi, Glauco

“…Objective To analyze the predictive factors for non‐sentinel lymph node (non‐SLN) metastasis in early‐stage cervical cancer. Methods We analyzed a series of…”
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The roles of PTEN, cMET, and p16 in resistance to cetuximab in head and neck squamous cell carcinoma by da Costa, Alexandre A. B. A., Costa, Felipe D’Almeida, Araújo, Daniel Vilarim, Camandaroba, Marcos Pedro Guedes, de Jesus, Victor Hugo Fonseca, Oliveira, Audrey, Alves, Ana Caroline Fonseca, Stecca, Carlos, Machado, Larissa, de Oliveira, Andrea Cruz Feraz, de Oliveira, Thiago Bueno, Nicolau, Ulisses Ribaldo, de Lima, Vladmir Cláudio Cordeiro

“…There is no established biomarker for cetuximab efficacy in recurrent head and neck squamous cell carcinoma (HNSCC). The aim of the present study was to…”
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Early High Calcium and Phosphorus Intake by Parenteral Nutrition Prevents Short‐term Bone Strength Decline in Preterm Infants by Pereira‐da‐Silva, L, Costa, AB, Pereira, L, Filipe, AF, Virella, D, Leal, E, Moreira, AC, Rosa, ML, Mendes, L, Serelha, M

“…ABSTRACT Background and Aim: Very premature newborns have an increased risk of low bone mass and metabolic bone disease. Most longitudinal studies report a…”
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Hypertension in a Brazilian Urban Slum Population by Unger, Alon, Felzemburgh, Ridalva D. M., Snyder, Robert E., Ribeiro, Guilherme S., Mohr, Sharif, Costa, Vinícius B. A., Melendez, Astrid X. T. O., Reis, Renato B., Santana, Francisco S., Riley, Lee W., Reis, Mitermayer G., Ko, Albert I.

“…Low- and middle-income countries account for the majority of hypertension disease burden. However, little is known about the distribution of this illness…”
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Local identifiability and sensitivity analysis of neuromuscular blockade and depth of hypnosis models by Silva, M.M, Lemos, J.M, Coito, A, Costa, B.A, Wigren, T, Mendonça, T

“…Abstract This paper addresses the local identifiability and sensitivity properties of two classes of Wiener models for the neuromuscular blockade and depth of…”
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The Impact of Addition of Consolidation Chemotherapy to Standard Cisplatin-Based Chemoradiotherapy in Uterine Cervical Cancer: Matter of Distant Relapse by Santos, Elizabeth S., Lima, João P. N. S., Chen, Michael J., Baiocchi, Glauco, da Costa, Alexandre A. B. A., Maya, Joyce M. L., Souza, Ronaldo P., Ribeiro, Adriana R. G., Guimarães, Andrea P. G., Sanches, Solange M., Mantoan, Henrique, Queiroz, Ana C. M., Fabri, Vanessa A., Castro, Fabrício S.

“…Background. Treatment of advanced uterine cervical cancer has advanced little in the last 15 years. Although two phase III trials showed survival benefit with…”
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Acute effects of mixed circuit training on hemodynamic and cardiac autonomic control in chronic hemiparetic stroke patients: A randomized controlled crossover trial by Fonseca, Guilherme F., Midgley, Adrian W., Billinger, Sandra A., Michalski, André C., Costa, Victor A. B., Monteiro, Walace, Farinatti, Paulo, Cunha, Felipe A.

“…Objectives: To investigate whether a single bout of mixed circuit training (MCT) can elicit acute blood pressure (BP) reduction in chronic hemiparetic stroke…”
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Characterization of organic matter in sediment cores of the Todos os Santos Bay, Bahia, Brazil, by elemental analysis and 13C NMR by Costa, A.B., Novotny, E.H., Bloise, A.C., de Azevedo, E.R., Bonagamba, T.J., Zucchi, M.R., Santos, V.L.C.S., Azevedo, A.E.G.

“…► The impact of human activity on the sediments of Todos os Santos Bay in Brazil was evaluated by EA and 13C NMR. ► This article reports a study of six…”
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Mixed circuit training acutely reduces arterial stiffness in patients with chronic stroke: a crossover randomized controlled trial by Michalski, André C., Ferreira, Arthur S., Midgley, Adrian W., Costa, Victor A. B., Fonseca, Guilherme F., da Silva, Nádia S. L., Borges, Juliana, Billinger, Sandra A., Cunha, Felipe A.

“…Purpose Investigate whether a single bout of mixed circuit training (MCT) can elicit changes in arterial stiffness in patients with chronic stroke. Second, to…”
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Forage Accumulation and Nutritional Characteristics of Brachiaria Cultivars Grown in a Semi-arid Environment by Rodrigues, J. G., Difante, G. dos S., Ítavo, L. C. V., Pereira, M. de G., Gurgel, A. L. C., Costa, A. B. G. da, Véras, E. L. de L., Monteiro, G. O. de A., Dias, A. M., Ítavo, C. C. B. F.

“…The evaluation of the nutritional value and parameters of ruminal fermentation of tropical forages is important, aiming at its efficient use in ruminant…”
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Grazing intensity as a management strategy in tropical grasses for beef cattle production: a meta-analysis by Costa, C.M., Difante, G.S., Costa, A.B.G., Gurgel, A.L.C., Ferreira Jr, M.A., Santos, G.T.

“…Correct pasture management associated with the adjustment of grazing intensity determines pasture persistence and the level of production per animal and per…”
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Photodynamic inactivation of biofilms formed by Candida spp., Trichosporon mucoides, and Kodamaea ohmeri by cationic nanoemulsion of zinc 2,9,16,23-tetrakis(phenylthio)-29H, 31H-phthalocyanine (ZnPc) by Junqueira, J. C., Jorge, A. O. C., Barbosa, J. O., Rossoni, R. D., Vilela, S. F. G., Costa, A. C. B. P., Primo, F. L., Gonçalves, J. M., Tedesco, A. C., Suleiman, J. M. A. H.

“…The biofilms formed by opportunistic yeasts serve as a persistent reservoir of infection and impair the treatment of fungal diseases. The aim of this study was…”
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Impairment after burns: a two-center, prospective report by Costa, B.A, Engrav, L.H, Holavanahalli, R, Lezotte, D.C, Patterson, D.R, Kowalske, K.J, Esselman, P.C

“…Impairment rating is regularly reported for trauma and other conditions but rarely for burns. The purposes of this study were: (1) to report impairment…”
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