Search Results - "Costa, Anna"
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The Performance of Several Docking Programs at Reproducing Protein-Macrolide-Like Crystal Structures
Published in Molecules (Basel, Switzerland) (17-01-2017)“…The accuracy of five docking programs at reproducing crystallographic structures of complexes of 8 macrolides and 12 related macrocyclic structures, all with…”
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2
A Survey on Transfer Learning for Multiagent Reinforcement Learning Systems
Published in The Journal of artificial intelligence research (01-01-2019)“…Multiagent Reinforcement Learning (RL) solves complex tasks that require coordination with other agents through autonomous exploration of the environment…”
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3
Actin-Interacting Amphidinolides: Syntheses and Mechanisms of Action of Amphidinolides X, J, and K
Published in Molecules (Basel, Switzerland) (01-07-2023)“…Amphidinolides are a family of more than forty macrolides of varying sizes and complex structures isolated from dinoflagellates of the genus . Although all of…”
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4
Coordination of Electric Vehicle Charging Through Multiagent Reinforcement Learning
Published in IEEE transactions on smart grid (01-05-2020)“…The number of Electric Vehicle (EV) owners is expected to significantly increase in the near future, since EVs are regarded as valuable assets both for…”
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Agents teaching agents: a survey on inter-agent transfer learning
Published in Autonomous agents and multi-agent systems (01-04-2020)“…While recent work in reinforcement learning (RL) has led to agents capable of solving increasingly complex tasks, the issue of high sample complexity is still…”
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6
Biphasic zinc compartmentalisation in a human fungal pathogen
Published in PLoS pathogens (01-05-2018)“…Nutritional immunity describes the host-driven manipulation of essential micronutrients, including iron, zinc and manganese. To withstand nutritional immunity…”
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COVID‐19 public health measures and respiratory viruses in children in Melbourne
Published in Journal of paediatrics and child health (01-12-2021)“…Aim To describe the epidemiology of respiratory viruses in children before and during the 2020 SARS‐CoV‐2 pandemic and the relationship to public health…”
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8
Computational Study of the Addition of Methanethiol to 40+ Michael Acceptors as a Model for the Bioconjugation of Cysteines
Published in Journal of organic chemistry (21-05-2021)“…A long series of Michael acceptors are studied computationally as potential alternatives to the maleimides that are used in most antibody–drug conjugates to…”
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Unexpected E‑to‑Z Isomerizations during the Negishi-Type Homocoupling of E-Iodoalkenes
Published in Journal of organic chemistry (04-10-2024)“…The direct insertion of Zn into olefin–halide bonds is a challenge. When (E)-alkenyl iodides were treated with a very large excess of Zn nanoparticles, in the…”
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10
Toward the production of bioblends for the automotive sector: Reuse of recycled polyamide 6,6 to prepare super‐tough biopolyethylene
Published in Journal of applied polymer science (20-11-2024)“…Plastics reuse is essential for promoting a sustainable future, especially by mitigating environmental impacts. Recycled polyamide 66 (PA66r) was reused for…”
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Shape-Related Toxicity of Titanium Dioxide Nanofibres
Published in PloS one (21-03-2016)“…Titanium dioxide (TiO2) nanofibres are a novel fibrous nanomaterial with increasing applications in a variety of fields. While the biological effects of TiO2…”
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12
Is the peroxisome proliferator-activated receptor gamma a putative target for epilepsy treatment? Current evidence and future perspectives
Published in Pharmacology & therapeutics (Oxford) (01-01-2023)“…The peroxisome proliferator-activated receptor gamma (PPARγ), which belongs to the family of nuclear receptors, has been mainly studied as an important factor…”
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13
Stochastic Abstract Policies: Generalizing Knowledge to Improve Reinforcement Learning
Published in IEEE transactions on cybernetics (01-01-2015)“…Reinforcement learning (RL) enables an agent to learn behavior by acquiring experience through trial-and-error interactions with a dynamic environment…”
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14
Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review
Published in Particle and fibre toxicology (05-01-2023)“…Adverse outcome pathways (AOPs) are conceptual frameworks that organize knowledge about biological interactions and toxicity mechanisms. They present a…”
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Maternal high-fat diet leads to hippocampal and amygdala dendritic remodeling in adult male offspring
Published in Psychoneuroendocrinology (01-09-2017)“…Graphical abstract…”
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Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay
Published in PloS one (15-09-2023)“…Toxicity evaluation of engineered nanomaterials is challenging due to the ever increasing number of materials and because nanomaterials (NMs) frequently…”
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Allopregnanolone and Pregnanolone Are Reduced in the Hippocampus of Epileptic Rats, but Only Allopregnanolone Correlates with Seizure Frequency
Published in Neuroendocrinology (01-06-2021)“…Neurosteroids modulate epileptic activity by interacting with the γ-aminobutyric acid type A receptor, but their brain levels are still undetermined. We aimed…”
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Modulation of therapeutic sensitivity by human papillomavirus
Published in Radiotherapy and oncology (01-09-2015)“…Abstract Human papillomaviruses (HPVs) are small double-stranded DNA viruses that pose significant public health concerns as the causative agent of…”
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(Z)‑Oxopropene-1,3-diyl, a Linker for the Conjugation of the Thiol Group of Cysteine with Amino-Derivatized Drugs
Published in Journal of organic chemistry (06-09-2019)“…We have developed a conjugation reaction based on the thia-Michael addition to activated triple bonds, which can be an alternative to maleimides, the most…”
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TiO₂ Nanosols Applied Directly on Textiles Using Different Purification Treatments
Published in Materials (24-11-2015)“…Self-cleaning applications using TiO₂ coatings on various supporting media have been attracting increasing interest in recent years. This work discusses the…”
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