Search Results - "Cosstick, R"

Synthesis of the flavour precursor, alliin, in garlic tissue cultures by Hughes, J., Tregova, A., Tomsett, A.B., Jones, M.G., Cosstick, R., Collin, H.A.

“…Uptake and metabolism of allyl thiol and allyl cysteine by undifferentiated callus of garlic and onion led to the formation of the flavour precursors alliin…”
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STUDIES ON THE ATTACHMENT OF DNA TO SILICA-COATED NANOPARTICLES THROUGH A DIELS-ALDER REACTION by Proupin-Perez, M., Cosstick, R., Liz-Marzan, L. M., Salgueiriño-Maceira, V., Brust, M.

“…A new method has been investigated for the functionalization of gold nanoparticles with DNA. Silica-coated nanoparticles functionalized with a maleimide have…”
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Sulfur biochemistry of garlic: the biosynthesis of flavor precursors by Collin, H.A, Hughes, J, Tregova, A, Milne, J.G.C, Werff, G. van der, Wilkinson, M, Jones, M.G, Tomsett, A.B, Cosstick, R, Trueman, L

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Aplastic anaemia associated with organochlorine pesticide: case reports and review of evidence by Rugman, F P, Cosstick, R

“…Three patients with aplastic anaemia had a history of substantial previous exposure to organochlorine pesticides. The temporal association between chemical…”
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Towards Multistep Nanostructure Synthesis: Programmed Enzymatic Self-Assembly of DNA/Gold Systems by Kanaras, Antonios G., Wang, Zhenxin, Bates, Andrew D., Cosstick, Richard, Brust, Mathias

“…Enzyme‐dependent assembly of DNA/gold nanostructures is achieved using DNA‐capped gold colloids and DNA processing enzymes. Particle‐bound DNA double strands…”
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Site-specific ligation of DNA-Modified gold nanoparticles activated by the restriction enzyme styl by Kanaras, A G, Wang, Z, Hussain, I, Brust, M, Cosstick, R, Bates, A D

“…Bound to be selective: A new method of enzymatically controlled nanoparticle assembly has been developed by using a restriction enzyme that recognizes an…”
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An approach to the stereoselective synthesis of Sp-dinucleoside phosphorothioates using phosphotriester chemistry by COSSTICK, R, WILLIAMS, D. M

“…An approach to the stereoselective synthesis of Sp- dinucleoside phosphorothioates has been investigated which utilizes phosphotriester chemistry. The…”
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Stabilization of the DNA I-Motif Structure by Incorporation of 3′-S-Phosphorothiolate Linkages by Brazier, John A., Fisher, Julie, Cosstick, Richard

“…A stable i: The i‐motif is a unique, four‐stranded DNA structure associated with cytosine‐rich sequences at the ends of human chromosomes. This is the first…”
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Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin by Jeyadevan, J. Prince, Bray, Patrick G, Chadwick, James, Mercer, Amy E, Byrne, Aoife, Ward, Stephen A, Park, B. Kevin, Williams, Dominic P, Cosstick, Rick, Davies, Jill, Higson, Adrian P, Irving, Ed, Posner, Gary H, O'Neill, Paul M

“…Four series of C-10 non-acetal dimers were prepared from key trioxane alcohol 10β-(2-hydroxyethyl)deoxoartemisinin (9b). All of the dimers prepared displayed…”
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Human DNA Polymerase α Uses a Combination of Positive and Negative Selectivity To Polymerize Purine dNTPs with High Fidelity by Beckman, Jeff, Kincaid, Kristi, Hocek, Michal, Spratt, Thomas, Engels, Joachim, Cosstick, Richard, Kuchta, Robert D

“…DNA polymerases accurately replicate DNA by incorporating mostly correct dNTPs opposite any given template base. We have identified the chemical features of…”
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Properties of the diadenosine tetraphosphate nucleoside analogue, bis (N6-adenosyl)dodecane, and its possible use in the treatment of disorders of purine metabolism by Chen, H, Cosstick, R, McLennan, A G

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Synthesis of oligonucleotides containing 3-deaza-2'-deoxyadenosine. Interaction of the oligonucleotides with the drug distamycin A by Cosstick, R, Lever, C

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Synthesis of cross-linked nucleosides as potential inhibitors of thymidine kinase by Cosstick, R, Nayyar, S Z

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Mechanism of the Escherichia coli DNA T:G-mismatch Endonuclease (Vsr protein) Probed with Thiophosphate-containing Oligodeoxynucleotides by Elliott, Sarah L., Brazier, John, Cosstick, Richard, Connolly, Bernard A.

“…The mechanism of the Escherichia coli DNA T:G mismatch endonuclease (Vsr) has been investigated using oligodeoxynucleotides substituted, at the scissile…”
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A second catalytic metal ion in a group I ribozyme by Cech, Thomas R, Weinstein, Lara B, Jones, B. C. N. M, Cosstick, Richard

“…Although only a subset of protein enzymes depend on the presence of a metal ion for their catalytic function, all naturally occurring RNA enzymes require metal…”
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Synthesis of phosphorothioamidites derived from 3′‐thio‐3′‐deoxythymidine and 3′‐thio‐2′,3′‐dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3′‐S‐phosphorothiolate linkage by Sabbagh, Ghalia, Fettes, Kevin J., Gosain, Rajendra, O’Neil, Ian A., Cosstick, Richard

“…The synthesis of N4‐benzoyl‐5′‐O‐dimethoxytrityl‐2′,3′‐dideoxy‐3′‐thiocytidine and its phosphorothioamidite is described for the first time, together with a…”
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Construction and Characterization of a Gold Nanoparticle Wire Assembled Using Mg2+-Dependent RNA−RNA Interactions by Bates, Andrew D, Callen, Benjamin P, Cooper, Jonathan M, Cosstick, Rick, Geary, Cody, Glidle, Andrew, Jaeger, Luc, Pearson, John L, Proupín-Pérez, María, Xu, Cigang, Cumming, David R. S

“…Magnesium-ion-mediated RNA−RNA loop−receptor interactions, in conjunction with gold nanoparticles derivatized with DNA, have been used to make self-assembled…”
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Towards Fluorous-Phase Synthesis of Nucleoside  -Peptides by Threlfall, R., Cosstick, R., Wada, T.

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Effect of Low Storage Temperature on Some of the Flavour Precursors in Garlic (Allium Sativum) by Hughes, J, Collin, H.A, Tregova, A, Tomsett, A.B, Cosstick, R, Jones, M.G

“…Garlic (Allium sativum) cloves were stored at ambient temperature and 4 degrees C for periods up to six months to establish the effect of position of the…”
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The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts by Shah, Rajvee, Cosstick, Richard, West, Stephen C.

“…The Escherichia coli RuvC protein resolves DNA intermediates produced during genetic recombination. In vitro, RuvC binds specifically to Holliday junctions and…”
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