Search Results - "Cossette, Michele"

Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of ClpP Protease by Leung, Elisa, Datti, Alessandro, Cossette, Michele, Goodreid, Jordan, McCaw, Shannon E., Mah, Michelle, Nakhamchik, Alina, Ogata, Koji, El Bakkouri, Majida, Cheng, Yi-Qiang, Wodak, Shoshana J., Eger, Bryan T., Pai, Emil F., Liu, Jun, Gray-Owen, Scott, Batey, Robert A., Houry, Walid A.

“…ClpP is a cylindrical serine protease whose ability to degrade proteins is regulated by the unfoldase ATP-dependent chaperones. ClpP on its own can only…”
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Development of Antibiotics That Dysregulate the Neisserial ClpP Protease by Binepal, Gursonika, Mabanglo, Mark F, Goodreid, Jordan D, Leung, Elisa, Barghash, Marim M, Wong, Keith S, Lin, Funing, Cossette, Michele, Bansagi, Jazmin, Song, Boxi, Balasco Serrão, Vitor Hugo, Pai, Emil F, Batey, Robert A, Gray-Owen, Scott D, Houry, Walid A

“…Evolving antimicrobial resistance has motivated the search for novel targets and alternative therapies. Caseinolytic protease (ClpP) has emerged as an enticing…”
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Novel, druglike 1,7-disubstituted 2,3,4,5-tetrahydro-1H-benzo[b]azepine-based selective inhibitors of human neuronal nitric oxide synthase (nNOS) by Annedi, Subhash C., Ramnauth, Jailall, Cossette, Michele, Maddaford, Shawn P., Dove, Peter, Rakhit, Suman, Andrews, John S., Porreca, Frank

“…R=various cyclic and acyclic basic amine side chains. Selective inhibitors of human neuronal nitric oxide synthase (nNOS). A novel class of 1,7-disubstituted…”
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Synthesis of Caseinolytic Protease Agonists Towards the Synthesis of the Natural Acyldepsipeptides by Cossette, Michele

“…Caseinolytic protease (ClpP) is a cylindrical protease forming the core of protein degradation machinery in eubacteria. ClpP is tightly regulated and is…”
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Comparison of anthropometric measures of men with HIV: Asymptomatic, symptomatic, and AIDS by Parisien, Chantal, Gélinas, Monique D, Cossette, Michèle

“…Objective Anthropometric measures were performed to determine differences in estimated fat mass, lean body mass, and body weight among three groups of men…”
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