Search Results - "Coso, Omar"

KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi's sarcoma by Medina, María Victoria, D Agostino, Agata, Ma, Qi, Eroles, Pilar, Cavallin, Lucas, Chiozzini, Chiara, Sapochnik, Daiana, Cymeryng, Cora, Hyjek, Elizabeth, Cesarman, Ethel, Naipauer, Julian, Mesri, Enrique A, Coso, Omar A

“…Kaposi's sarcoma-associated herpesvirus (KSHV) vGPCR is a constitutively active G protein-coupled receptor that subverts proliferative and inflammatory…”
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Unveiling the role of KSHV‐infected human mesenchymal stem cells in Kaposi's sarcoma initiation by Lacunza, Ezequiel, Ahuja, Anuj, Coso, Omar A., Abba, Martin, Ramos, Juan Carlos, Cesarman, Ethel, Mesri, Enrique A., Naipauer, Julian

“…Kaposi's sarcoma (KS) may derive from Kaposi's sarcoma herpesvirus (KSHV)‐infected human mesenchymal stem cells (hMSCs) that migrate to sites characterized by…”
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Autophagy in Viral Development and Progression of Cancer by Suares, Alejandra, Medina, María Victoria, Coso, Omar

“…Autophagy is a complex degradative process by which eukaryotic cells capture cytoplasmic components for subsequent degradation through lysosomal hydrolases…”
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An interplay between the p38 MAPK pathway and AUBPs regulates c-fos mRNA stability during mitogenic stimulation by Degese, Maria Sol, Tanos, Tamara, Naipauer, Julian, Gingerich, Tim, Chiappe, Diego, Echeverria, Pablo, LaMarre, Jonathan, Gutkind, J Silvio, Coso, Omar A

“…Mitogen-activated protein kinase (MAPK) pathways constitute key regulatory elements linking extracellular stimuli to nuclear gene expression. Immediate-early…”
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A major role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes by Sapochnik, Daiana, Raimondi, Ana R., Medina, Victoria, Naipauer, Julian, Mesri, Enrique A., Coso, Omar

“…Kaposi’s sarcoma (KS) is the most common tumor in AIDS patients. The highly vascularized patient’s skin lesions are composed of cells derived from the…”
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Tristetraprolin promotes survival of mammary progenitor cells by restraining TNFα levels by Stedile, Micaela, Lara Montero, Angela, García Solá, Martín Emilio, Goddio, María Victoria, Beckerman, Inés, Bogni, Emilia, Ayre, Marina, Naguila, Zaira, Coso, Omar A, Kordon, Edith C

“…Tristetraprolin (TTP) is an RNA binding protein that destabilizes mRNAs of factors involved in proliferation, invasiveness, and inflammation. Disruption of the…”
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Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data by Degese, María S, Mendizabal, Javier E, Gandini, Norberto A, Gutkind, J. Silvio, Molinolo, Alfredo, Hewitt, Stephen M, Curino, Alejandro C, Coso, Omar A, Facchinetti, María M

“…Abstract While changes in heme oxygenase (HO-1) in lung cancer have already been reported, conflicting results were obtained for enzyme expression in human…”
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R-spondin3 Is Associated with Basal-Progenitor Behavior in Normal and Tumor Mammary Cells by Tocci, Johanna M, Felcher, Carla M, García Solá, Martín E, Goddio, María Victoria, Zimberlin, María Noel, Rubinstein, Natalia, Srebrow, Anabella, Coso, Omar A, Abba, Martín C, Meiss, Roberto P, Kordon, Edith C

“…R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role…”
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Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT by Srebrow, Anabella, Blaustein, Matías, Pelisch, Federico, Tanos, Tamara, Muñoz, Manuel J, Wengier, Diego, Quadrana, Leandro, Sanford, Jeremy R, Muschietti, Jorge P, Kornblihtt, Alberto R, Cáceres, Javier F, Coso, Omar A

“…Serine/arginine-rich (SR) proteins are important regulators of mRNA splicing. Several postsplicing activities have been described for a subset of shuttling SR…”
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A Non-Coding RNA Network Involved in KSHV Tumorigenesis by Naipauer, Julián, García Solá, Martín E, Salyakina, Daria, Rosario, Santas, Williams, Sion, Coso, Omar, Abba, Martín C, Mesri, Enrique A, Lacunza, Ezequiel

“…Regulatory pathways involving non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNA), have gained great relevance due to their…”
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The use of alternative polyadenylation sites renders integrin β1 (Itgb1) mRNA isoforms with differential stability during mammary gland development by Naipauer, Julian, Gattelli, Albana, Degese, Maria Sol, Slomiansky, Victoria, Wertheimer, Eva, LaMarre, Jonathan, Castilla, Lucio, Abba, Martin, Kordon, Edith C, Coso, Omar A

“…Integrins are heterodimeric cell-surface adhesion receptors that play a critical role in tissue development. Characterization of the full-length mRNA encoding…”
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Activation and Induction of NUR77/NURR1 in Corticotrophs by CRH/cAMP: Involvement of Calcium, Protein Kinase A, and MAPK Pathways by Kovalovsky, Damián, Refojo, Damián, Liberman, Ana Clara, Hochbaum, Daniel, Pereda, Marcelo Paez, Coso, Omar A, Stalla, Günter K, Holsboer, Florian, Arzt, Eduardo

“…Nur factors are critical for proopiomelanocortin (POMC) induction by CRH in corticotrophs, but the pathways linking CRH to Nur are unknown. In this study we…”
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Oral and anal microbiome from HIV-exposed individuals: role of host-associated factors in taxa composition and metabolic pathways by Lacunza, Ezequiel, Fink, Valeria, Salas, María E., Canzoneri, Romina, Naipauer, Julián, Williams, Sion, Coso, Omar, Sued, Omar, Cahn, Pedro, Mesri, Enrique A., Abba, Martín C.

“…Evidence indicates that the microbiome plays a significant role in HIV immunopathogenesis and associated complications. This study aimed to characterize the…”
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Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light by Tanos, Tamara, Marinissen, Maria Julia, Leskow, Federico Coluccio, Hochbaum, Daniel, Martinetto, Horacio, Gutkind, J Silvio, Coso, Omar A

“…Exposure to sources of UV radiation, such as sunlight, induces a number of cellular alterations that are highly dependent on its ability to affect gene…”
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Role of 3′-5′-cyclic adenosine monophosphate on the epidermal growth factor dependent survival in mammary epithelial cells by Grinman, Diego Y., Romorini, Leonardo, Presman, Diego M., Rocha-Viegas, Luciana, Coso, Omar A., Davio, Carlos, Pecci, Adali

“…Epidermal growth factor (EGF) has been suggested to play a key role in the maintenance of epithelial cell survival during lactation. Previously, we…”
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Extracellular Acidosis Induces Neutrophil Activation by a Mechanism Dependent on Activation of Phosphatidylinositol 3-Kinase/Akt and ERK Pathways by Martinez, Diego, Vermeulen, Monica, Trevani, Analia, Ceballos, Ana, Sabatte, Juan, Gamberale, Romina, Alvarez, Maria Eugenia, Salamone, Gabriela, Tanos, Tamara, Coso, Omar A, Geffner, Jorge

“…Inflammation in peripheral tissues is usually associated with the development of local acidosis; however, there are few studies aimed at analyzing the…”
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Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways by Kovalovsky, Damián, Refojo, Damián, Liberman, Ana Clara, Hochbaum, Daniel, Pereda, Marcelo Paez, Coso, Omar A, Stalla, Günter K, Holsboer, Florian, Arzt, Eduardo

“…Nur factors are critical for proopiomelanocortin (POMC) induction by CRH in corticotrophs, but the pathways linking CRH to Nur are unknown. In this study we…”
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Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor by Marinissen, Maria Julia, Tanos, Tamara, Bolós, Marta, de Sagarra, Maria Rosa, Coso, Omar A, Cuadrado, Antonio

“…Heme oxygenase-1 (HO-1), the inducible enzyme responsible for the rate-limiting step in the heme catabolism, is expressed in AIDS-Kaposi sarcoma (KS) lesions…”
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Bcl-XL mediates epidermal growth factor dependent cell survival in HC11 mammary epithelial cells by Romorini, Leonardo, Coso, Omar A, Pecci, Adali

“…Apoptosis is the predominant process controlling cell deletion during post-lactational mammary gland remodeling. The members of the Bcl-2 protein family, whose…”
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Tumor necrosis factor alpha induces LIF expression through ERK1/2 activation in mammary epithelial cells by Levy, Carolina Schere, Slomiansky, Victoria, Gattelli, Albana, Nahmod, Karen, Pelisch, Federico, Blaustein, Matias, Srebrow, Anabella, Coso, Omar A., Kordon, Edith C.

“…It has been reported that expression of tumor necrosis factor superfamily members occur at the onset of the mammary gland post‐lactational involution. One of…”
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