Search Results - "Cosmi, Carlo"

Evaluation of the efficacy and safety of deferiprone compared with deferasirox in paediatric patients with transfusion-dependent haemoglobinopathies (DEEP-2): a multicentre, randomised, open-label, non-inferiority, phase 3 trial by Maggio, Aurelio, Kattamis, Antonis, Felisi, Mariagrazia, Reggiardo, Giorgio, El-Beshlawy, Amal, Bejaoui, Mohamed, Sherief, Laila, Christou, Soteroula, Cosmi, Carlo, Della Pasqua, Oscar, Del Vecchio, Giovanni Carlo, Filosa, Aldo, Cuccia, Liana, Hassab, Hoda, Kreka, Manika, Origa, Raffaella, Putti, Maria Caterina, Spino, Michael, Telfer, Paul, Tempesta, Bianca, Vitrano, Angela, Tsang, Yu Chung, Zaka, Ariana, Tricta, Fernando, Bonifazi, Donato, Ceci, Adriana

“…Transfusion-dependent haemoglobinopathies require lifelong iron chelation therapy with one of the three iron chelators (deferiprone, deferasirox, or…”
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Stratification for Age in Transfusion-Dependent Thalassemia by Pepe, Alessia, Pistoia, Laura, Rocca, Mario, Palazzi, Giovanni, Sorrentino, Francesco, Maggio, Aurelio, Quarta, Antonella, Cosmi, Carlo, Argento, Crocetta, Armari, Sabrina, Peritore, Giuseppe, Oliva, Matteo, Positano, Vincenzo, Meloni, Antonella

“…▪ Introduction. Transfusion-dependent β-thalassemia (TDT) is the most severe clinical form of β-thalassemia and requires regular long-term red cell…”
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The Strong Link between Pancreas and Heart in Thalassemia Major by Meloni, Antonella, Pistoia, Laura, Guerrini, Giulia, Sallì, Alessia, Cosmi, Carlo, Sarli, Roberto, Smacchia, Maria Paola, Carrà, Annamaria, Maggio, Aurelio, Positano, Vincenzo, Missere, Massimiliano, Pepe, Alessia

“…Background. Some preliminary data have postulated a correlation between pancreatic iron overload and heart iron and function in thalassemia major (TM)…”
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Population pharmacokinetics and dosing recommendations for the use of deferiprone in children younger than 6 years by Bellanti, Francesco, Del Vecchio, Giovanni C., Putti, Maria C., Maggio, Aurelio, Filosa, Aldo, Cosmi, Carlo, Mangiarini, Laura, Spino, Michael, Connelly, John, Ceci, Adriana, Della Pasqua, Oscar

“…Aims Despite long clinical experience with deferiprone, there is limited information on its pharmacokinetics in children aged <6 years. Here we assess the…”
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Model-Based Optimisation of Deferoxamine Chelation Therapy by Bellanti, Francesco, Del Vecchio, Giovanni C., Putti, Maria C., Cosmi, Carlo, Fotzi, Ilaria, Bakshi, Suruchi D., Danhof, Meindert, Della Pasqua, Oscar

“…Purpose Here we show how a model-based approach may be used to provide further insight into the role of clinical and demographic covariates on the progression…”
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Early response does not predict outcome in children and adolescents with chronic myeloid leukaemia treated with high‐dose imatinib by Giona, Fiorina, Saglio, Giuseppe, Santopietro, Michelina, Menna, Giuseppe, Putti, Maria Caterina, Micalizzi, Concetta, Iaria, Grazia, Santoro, Nicola, Ladogana, Saverio, Mura, Rosamaria, Burnelli, Roberta, Consarino, Caterina, Cosmi, Carlo, Moleti, Maria Luisa, Leszl, Anna, Tucci, Francesca, Nanni, Mauro, Diverio, Daniela, Biondi, Andrea, Locatelli, Franco, Foà, Robin

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Acute lymphoblastic leukemia in a nine-year-old girl with isodicentric chromosome 15 syndrome by Antonucci, Roberto, Vacca, Nadia, Ghisu, Elisa, Acquaviva, Gloria, Cosmi, Carlo, Marinaro, Anna Maria, Locci, Cristian, Fozza, Claudio

“…Isodicentric chromosome 15, also called idic(15), is a rare chromosomal abnormality resulting from inverted duplication of proximal 15q. It is associated with…”
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Left Ventricular Global Function Index and Left Ventricular Mass Volume Ratio By CMR: Relation with Heart Failure in Thalassemia Major Patients by Meloni, Antonella, De Franceschi, Lucia, Maddaloni, Domenico, Carollo, Sabrina, Sarli, Roberto, Cosmi, Carlo, Ruffo, Giovan Battista, Neri, Maria Giovanna, Resta, Maria Chiara, Vallone, Antonino, Positano, Vincenzo, Pepe, Alessia

“…Introduction: Recently two novels indicators of left ventricular (LV) performance assessed by Cardiovascular Magnetic Resonance (CMR) have been introduced: the…”
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A T2 MRI Prospective Survey on Cardiac and Hepatic Iron in Non-Trasfusion-Dependent Thalassemia Intermedia Patients Treated with Desferrioxamine by Meloni, Antonella, Maggio, Aurelio, Cosmi, Carlo, D’Ambrosio, Alfonso, Facchini, Elena, Chiari, Roberta, Sardella, Leonardo, Grassedonio, Emanuele, Valeri, Gianluca, Neri, Maria Giovanna, Positano, Vincenzo, Pepe, Alessia

“…Background. In thalassemia intermedia (TI) patients no observational study prospectively evaluated in the real life the efficacy of the desferrioxamine (DFO)…”
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Detection of myocardial iron overload by two-dimensional speckle tracking in patients with beta-thalassaemia major: a combined echocardiographic and T2 segmental CMR study by Pizzino, Fausto, Meloni, Antonella, Terrizzi, Anna, Casini, Tommaso, Spasiano, Anna, Cosmi, Carlo, Allò, Massimo, Zito, Concetta, Carerj, Scipione, Aquaro, Giovanni Donato, Di Bella, Gianluca, Pepe, Alessia

“…We aimed to evaluate the role of two-dimensional speckle tracking imaging (2DSTI) in detecting early changes of myocardial deformation in patients affected by…”
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The prognostic value of biological markers in paediatric Hodgkin lymphoma by Farruggia, Piero, Puccio, Giuseppe, Sala, Alessandra, Todesco, Alessandra, Buffardi, Salvatore, Garaventa, Alberto, Bottigliero, Gaetano, Bianchi, Maurizio, Zecca, Marco, Locatelli, Franco, Pession, Andrea, Pillon, Marta, Favre, Claudio, D'Amico, Salvatore, Provenzi, Massimo, Trizzino, Angela, Zanazzo, Giulio Andrea, Sau, Antonella, Santoro, Nicola, Murgia, Giulio, Casini, Tommaso, Mascarin, Maurizio, Burnelli, Roberta

“…Abstract Background Many biological and inflammatory markers have been proposed as having a prognostic value at diagnosis of Hodgkin lymphoma (HL), but very…”
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Early Response Does Not Impact on the Long-Term Outcome of Children and Adolescents with Chronic Myeloid Leukemia Treated with High-Dose Imatinib. the Italian Experience by Giona, Fiorina, Saglio, Giuseppe, Santopietro, Michelina, Menna, Giuseppe, Iaria, Grazia, Putti, Maria Caterina, Micalizzi, Concetta, Santoro, Nicola, Ladogana, Saverio, Mura, Rosa Maria, Burnelli, Roberta, Consarino, Caterina, Cosmi, Carlo, Moleti, Maria Luisa, Varotto, Stefania, Tucci, Francesca, Nanni, Mauro, Diverio, Daniela, Biondi, Andrea, Locatelli, Franco, Foà, Robin

“…Reports in adults have shown that a BCR-ABL1 IS <10% at 3 months after the start of imatinib (IM) can predict better clinical outcome in chronic myeloid…”
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Acute lymphoblastic leukemia in a nine-year-old girl with isodicentric chromosome 15 syndrome by Antonucci, Roberto, Vacca, Nadia, Ghisu, Elisa, Acquaviva, Gloria, Cosmi, Carlo, Marinaro, Anna Maria, Locci, Cristian, Fozza, Claudio

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