Search Results - "Coskun, Kübra A"
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Designing Specific HSP70 Substrate Binding Domain Inhibitor for Perturbing Protein Folding Pathways to Inhibit Cancer Mechanism
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…HSP70 is a survival factor for tumor cells in transformation and in tumor progression as well as in anti-apoptotic response. Several inhibitors targeting HSP70…”
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Involvement of Metabolites and Non-coding RNAs in Diseases
Published in Current pharmaceutical biotechnology (01-01-2023)“…Non-coding RNAs have a role in gene regulation and cellular metabolism control. Metabolism produces metabolites which are small molecules formed during the…”
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CO-releasing properties and anticancer activities of manganese complexes with imidazole/benzimidazole ligands
Published in Journal of coordination chemistry (16-11-2016)“…Carbon monoxide (CO) is an important signaling molecule which plays significant roles in the pathogenesis of cancer. CO is produced by enzymatic degradation of…”
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Heat shock protein 40-Gok1 isolation from Toxoplasma gondii RH strain
Published in Protein and peptide letters (01-12-2013)“…Toxoplasma gondii is ubiquitous obligate intracellular parasite and is one of the most important pathogen for humans and animals. In humans, T. gondii has two…”
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Anticancer activities of manganese-based photoactivatable CO-releasing complexes (PhotoCORMs) with benzimidazole derivative ligands
Published in Transition metal chemistry (Weinheim) (01-05-2017)“…Carbon monoxide is an important signaling molecule which is produced by heme oxygenase-1. CO shows antiproliferative activity against cancer cells; hence,…”
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