Search Results - "Cosgaya, M."

NGF Controls Axonal Receptivity to Myelination by Schwann Cells or Oligodendrocytes by Chan, Jonah R, Watkins, Trent A, Cosgaya, José M, Zhang, ChunZhao, Chen, Lian, Reichardt, Louis F, Shooter, Eric M, Barres, Ben A

“…Axons dictate whether or not they will become myelinated in both the central and peripheral nervous systems by providing signals that direct the development of…”
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Anterograde Transport and Secretion of Brain-Derived Neurotrophic Factor along Sensory Axons Promote Schwann Cell Myelination by Ng, Benjamin K, Chen, Lian, Mandemakers, Wilhelm, Cosgaya, Jose M, Chan, Jonah R

“…The neurotrophin brain-derived neurotrophic factor (BDNF) inhibits Schwann cell (SC) migration and promotes myelination via the p75 neurotrophin receptor…”
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Pro-apoptotic signaling induced by Retinoic acid and dsRNA is under the control of Interferon Regulatory Factor-3 in breast cancer cells by Bernardo, Ana R., Cosgaya, José M., Aranda, Ana, Jiménez-Lara, Ana M.

“…Breast cancer is one of the most lethal malignancies for women. Retinoic acid (RA) and double-stranded RNA (dsRNA) are considered signaling molecules with…”
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First description and validation of a new method for estimating aortic stenosis burden and predicting the functional response to TAVI by de la Torre Hernandez, Jose M., Veiga Fernandez, Gabriela, Ben-Assa, Eyal, Iribarren, Julia, Sainz Laso, Fermin, Lee, Dae-Hyun, Ruisanchez Villar, Cristina, Lerena, Piedad, Garcia Camarero, Tamara, Iribarren Sarrias, Jose L., Cuesta Cosgaya, Jose M., Maza Fernandez, Maria E., Garilleti, Celia, Fradejas-Sastre, Victor, Benito, Mercedes, Barrera, Sergio, Gil Ongay, Aritz, Vazquez de Prada, Jose A., Zueco, Javier

“…BackgroundUp to one-fifth of patients continue to have poor quality of life after transcatheter aortic valve implantation (TAVI), with an additional similar…”
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Intraprocedural delayed reassessment of paravalvular regurgitation in TAVR significantly reduces the use of postdilatation by De la Torre Hernandez, Jose M., Veiga Fernandez, Gabriela, Barrera, Sergio, Sainz Laso, Fermin, Lee, Dae‐Hyun, Ruisanchez Villar, Cristina, Lerena, Piedad, Garcia Camarero, Tamara, Cuesta Cosgaya, Jose M., Gil Ongay, Aritz, Zueco, Javier

“…Objectives We sought to investigate the effect of a 15‐min delayed intraprocedural reassessment of paravalvular aortic regurgitation (PVR) after an immediate…”
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The neurotrophin receptor p75(NTR) as a positive modulator of myelination by Cosgaya, Jose M, Chan, Jonah R, Shooter, Eric M

“…Schwann cells in developing and regenerating peripheral nerves express elevated levels of the neurotrophin receptor p75NTR. Neurotrophins are key mediators of…”
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BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system by Tolwani, Ravi J., Cosgaya, José M., Varma, Sushama, Jacob, Reza, Kuo, Lydia E., Shooter, Eric M.

“…The neurotrophin brain‐derived neurotrophic factor (BDNF) is an endogenous regulator of the myelination process during development in the peripheral nervous…”
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A new integrative approach to assess aortic stenosis burden and predict objective functional improvement after TAVR by de la Torre Hernandez, Jose M, Veiga Fernandez, Gabriela, Ben-Assa, Eyal, Sainz Laso, Fermin, Lee, Dae-Hyun, Ruisanchez Villar, Cristina, Lerena, Piedad, Garcia Camarero, Tamara, Cuesta Cosgaya, Jose M, Fradejas-Sastre, Victor, Benito, Mercedes, Barrera, Sergio, Garcia-Unzueta, Maria T, Brown, Jonathan, Gil Ongay, Aritz, Zueco, Javier, Vazquez de Prada, Jose A, Edelman, Elazer R

“…A non-negligible rate of patients undergoing transcatheter aortic valve replacement (TAVR) do not report symptomatic improvement or even die in the…”
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BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus by Tolwani, R.J, Buckmaster, P.S, Varma, S, Cosgaya, J.M, Wu, Y, Suri, C, Shooter, E.M

“…There is increasing evidence that brain-derived neurotrophic factor (BDNF) modulates synaptic and morphological plasticity in the developing and mature nervous…”
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Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking by Saxena, Smita, Howe, Charles L., Cosgaya, José M., Steiner, Pascal, Hirling, Harald, Chan, Jonah R., Weis, Joachim, Krüttgen, Alex

“…NGF binds to two receptors, p75NTR and TrkA. The endosomal trafficking of receptors is of emerging importance for the understanding of their signaling. We…”
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Circulating microRNAs in Huntington’s disease: Emerging mediators in metabolic impairment by Díez-Planelles, C., Sánchez-Lozano, P., Crespo, M.C., Gil-Zamorano, J., Ribacoba, R., González, N., Suárez, E., Martínez-Descals, A., Martínez-Camblor, P., Álvarez, V., Martín-Hernández, R., Huerta-Ruíz, I., González-García, I., Cosgaya, J.M., Visioli, F., Dávalos, A., Iglesias-Gutiérrez, E., Tomás-Zapico, C.

“…[Display omitted] Huntington’s disease (HD) is a hereditary neurodegenerative disease, with peripheral consequences that negatively contribute to quality of…”
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Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons by Wu, Y.J., Krüttgen, A., Möller, J.C., Shine, D., Chan, J.R., Shooter, E.M., Cosgaya, J.M.

“…Neurotrophins (NTs) play an important role in the modulation of synaptic transmission and in morphological changes in synaptic structures. Although there is…”
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Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells by Bernardo, A R, Cosgaya, J M, Aranda, A, Jiménez-Lara, A M

“…Due to its ability to regulate the growth, differentiation and apoptosis of cancer cells, retinoic acid (RA) is considered a signaling molecule with promising…”
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Differences in the surface binding and endocytosis of neurotrophins by p75NTR by Saxena, Smita, Howe, Charles L, Cosgaya, José M, Hu, Minjie, Weis, Joachim, Krüttgen, Alex

“…Neurotrophins transmit signals retrogradely from synapses to cell bodies by two different types of surface receptors, p75NTR and Trks. Compared to TrkA, the…”
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Nerve growth factor and ras regulate beta-amyloid precursor protein gene expression in PC12 cells by Cosgaya, J M, Latasa, M J, Pascual, A

“…The beta-amyloid protein, the major component of the vascular and plaque amyloid deposits that characterize Alzheimer's disease, derives from a larger…”
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Neurotrophins are Key Mediators of the Myelination Program in the Peripheral Nervous System by Chan, Jonah R., Cosgaya, José Miguel, Wu, Yong Jian, Shooter, Eric M.

“…Although knowledge of the functions of neurotrophins has advanced rapidly in recent years, studies concerning the involvement of neurotrophins in…”
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Palmitoylation of the p75 neurotrophin receptor has no effect on its interaction with TrkA or on TrkA-mediated down-regulation of cell adhesion molecules by Vesa, Jouni, Krüttgen, Alex, Cosgaya, Jose M., Shooter, Eric M.

“…The short‐ and long‐term effects of nerve growth factor (NGF) were studied on fibroblast cell lines stably expressing both TrkA and either wild‐type p75 or a…”
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Retinoic acid induces secretion of transforming growth factors by PC12 pheochromocytoma cells by COSGAYA, J. M, PERONA, R, ARANDA, A

“…Conditioned medium from PC12 cells incubated with retinoic acid (RA) increases [3H]thymidine incorporation in normal rat kidney (NRK) fibroblasts and 3D9…”
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Comparison of the effects of retinoic acid and nerve growth factor on PC12 cell proliferation, differentiation, and gene expression by Cosgaya, J M, Garcia-Villalba, P, Perona, R, Aranda, A

“…Retinoic acid (RA) produced a dose-dependent inhibition of PC12 cell growth and the appearance of cell clusters without neurite extension. RA-induced cell…”
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Influence of Ras and retinoic acid on nerve growth factor induction of transin gene expression in PC12 cells by COSGAYA, J. M, RECIO, J. A, ARANDA, A

“…Nerve growth factor (NGF)- and ras-induced neuronal differentiation of PC12 cells is accompanied by expression of transin, a secreted metalloproteinase…”
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