Search Results - "Cosby, Alexia G."
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Macrocyclic 1,2-Hydroxypyridinone-Based Chelators as Potential Ligands for Thorium-227 and Zirconium-89 Radiopharmaceuticals
Published in Inorganic chemistry (18-12-2023)“…Thorium-227 (227Th) is an α-emitting radionuclide that has shown preclinical and clinical promise for use in targeted α-therapy (TAT), a type of molecular…”
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2
Multiplex and In Vivo Optical Imaging of Discrete Luminescent Lanthanide Complexes Enabled by In Situ Cherenkov Radiation Mediated Energy Transfer
Published in Journal of the American Chemical Society (23-06-2021)“…Recently, we pioneered the application of Cherenkov radiation (CR) of radionuclides for the in situ excitation of discrete Eu(III) and Tb(III) complexes. CR…”
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3
A High-Throughput Method To Measure Relative Quantum Yield of Lanthanide Complexes for Bioimaging
Published in Inorganic chemistry (19-08-2019)“…Luminescent lanthanides provide a promising alternative to organic chromophores for cellular bioimaging and bioassay applications; efficacy is closely governed…”
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4
Cherenkov Radiation‐Mediated In Situ Excitation of Discrete Luminescent Lanthanide Complexes
Published in Angewandte Chemie International Edition (19-11-2018)“…Lanthanide luminescence, while ideal for in vivo applications owing to sharp emission bands within the optical window, requires high‐intensity,…”
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5
Validation of a post-radiolabeling bioconjugation strategy for radioactive rare earth complexes with minimal structural footprint
Published in Chemical communications (Cambridge, England) (13-12-2022)“…The nine-coordinate aza-macrocycle DO3Apic-NO2 and its kinetically inert rare earth complexes [M(DO3A-pic-NO2)]- (M = La, Tb, Eu, Lu, Y) can be readily…”
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6
Insights into the Magnetic Properties of Sub-10 nm Iron Oxide Nanocrystals through the Use of a Continuous Growth Synthesis
Published in Chemistry of materials (11-09-2018)“…Most studies on iron oxide nanocrystals (NCs) suggest that the magnetic properties depend strongly on size for diameters below 10 nm, but there is less…”
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7
Accessing lanthanide-based, in situ illuminated optical turn-on probes by modulation of the antenna triplet state energy
Published in Chemical science (Cambridge) (14-07-2021)“…Luminescent lanthanides possess ideal properties for biological imaging, including long luminescent lifetimes and emission within the optical window. Here, we…”
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8
General Approach to Direct Measurement of the Hydration State of Coordination Complexes in the Gas Phase: Variable Temperature Mass Spectrometry
Published in Journal of the American Chemical Society (18-09-2019)“…The formation of ternary aqua complexes of metal-based diagnostics and therapeutics is closely correlated to their in vivo efficacy but approaches to quantify…”
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9
Evolution of Atomic-Level Structure in Sub-10 Nanometer Iron Oxide Nanocrystals: Influence on Cation Occupancy and Growth Rates
Published in ACS nano (26-05-2020)“…Spinel iron oxide nanocrystals (NCs) have been reported to have atomic-level core and surface structural features that differ from those of the bulk material…”
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10
Slow Magnetic Relaxation in a Californium Complex
Published in Journal of the American Chemical Society (20-11-2024)“…We report the synthesis and characterization of the macrocyclic californium derivative Na[Cf(H2O)(DOTA)] (DOTA =…”
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11
Siderocalin fusion proteins enable a new Y/Y theranostic approach
Published in RSC chemical biology (03-08-2023)“…The mammalian protein siderocalin binds bacterial siderophores and their iron complexes through cation-π and electrostatic interactions, but also displays high…”
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12
Siderocalin fusion proteins enable a new 86 Y/ 90 Y theranostic approach
Published in RSC chemical biology (03-08-2023)“…The mammalian protein siderocalin binds bacterial siderophores and their iron complexes through cation-π and electrostatic interactions, but also displays high…”
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13
Siderocalin fusion proteins enable a new 86Y/90Y theranostic approach
Published in RSC chemical biology (03-08-2023)“…The mammalian protein siderocalin binds bacterial siderophores and their iron complexes through cation-π and electrostatic interactions, but also displays high…”
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Journal Article -
14
Cherenkov Radiation‐Mediated In Situ Excitation of Discrete Luminescent Lanthanide Complexes
Published in Angewandte Chemie (19-11-2018)“…Lanthanide luminescence, while ideal for in vivo applications owing to sharp emission bands within the optical window, requires high‐intensity,…”
Get full text
Journal Article -
15
Accessing lanthanide-based, illuminated optical turn-on probes by modulation of the antenna triplet state energy
Published in Chemical science (Cambridge) (14-07-2021)“…Luminescent lanthanides possess ideal properties for biological imaging, including long luminescent lifetimes and emission within the optical window. Here, we…”
Get full text
Journal Article