Search Results - "Cosby, Alexia G."

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  1. 1

    Macrocyclic 1,2-Hydroxypyridinone-Based Chelators as Potential Ligands for Thorium-227 and Zirconium-89 Radiopharmaceuticals by Woods, Joshua J., Cosby, Alexia G., Wacker, Jennifer N., Aguirre Quintana, Luis M., Peterson, Appie, Minasian, Stefan G., Abergel, Rebecca J.

    Published in Inorganic chemistry (18-12-2023)
    “…Thorium-227 (227Th) is an α-emitting radionuclide that has shown preclinical and clinical promise for use in targeted α-therapy (TAT), a type of molecular…”
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    Journal Article
  2. 2

    Multiplex and In Vivo Optical Imaging of Discrete Luminescent Lanthanide Complexes Enabled by In Situ Cherenkov Radiation Mediated Energy Transfer by Martin, Kirsten E, Cosby, Alexia G, Boros, Eszter

    Published in Journal of the American Chemical Society (23-06-2021)
    “…Recently, we pioneered the application of Cherenkov radiation (CR) of radionuclides for the in situ excitation of discrete Eu­(III) and Tb­(III) complexes. CR…”
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    Journal Article
  3. 3

    A High-Throughput Method To Measure Relative Quantum Yield of Lanthanide Complexes for Bioimaging by Cosby, Alexia G, Quevedo, Gregory, Boros, Eszter

    Published in Inorganic chemistry (19-08-2019)
    “…Luminescent lanthanides provide a promising alternative to organic chromophores for cellular bioimaging and bioassay applications; efficacy is closely governed…”
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    Journal Article
  4. 4

    Cherenkov Radiation‐Mediated In Situ Excitation of Discrete Luminescent Lanthanide Complexes by Cosby, Alexia G., Ahn, Shin Hye, Boros, Eszter

    Published in Angewandte Chemie International Edition (19-11-2018)
    “…Lanthanide luminescence, while ideal for in vivo applications owing to sharp emission bands within the optical window, requires high‐intensity,…”
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    Journal Article
  5. 5

    Validation of a post-radiolabeling bioconjugation strategy for radioactive rare earth complexes with minimal structural footprint by Lengacher, Raphael, Cosby, Alexia G, Śmiłowicz, Dariusz, Boros, Eszter

    “…The nine-coordinate aza-macrocycle DO3Apic-NO2 and its kinetically inert rare earth complexes [M(DO3A-pic-NO2)]- (M = La, Tb, Eu, Lu, Y) can be readily…”
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    Journal Article
  6. 6

    Insights into the Magnetic Properties of Sub-10 nm Iron Oxide Nanocrystals through the Use of a Continuous Growth Synthesis by Cooper, Susan R, Plummer, L. Kenyon, Cosby, Alexia G, Lenox, Philip, Jander, Albrecht, Dhagat, Pallavi, Hutchison, James E

    Published in Chemistry of materials (11-09-2018)
    “…Most studies on iron oxide nanocrystals (NCs) suggest that the magnetic properties depend strongly on size for diameters below 10 nm, but there is less…”
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  7. 7

    Accessing lanthanide-based, in situ illuminated optical turn-on probes by modulation of the antenna triplet state energy by Cosby, Alexia G, Woods, Joshua J, Nawrocki, Patrick, Sørensen, Thomas J, Wilson, Justin J, Boros, Eszter

    Published in Chemical science (Cambridge) (14-07-2021)
    “…Luminescent lanthanides possess ideal properties for biological imaging, including long luminescent lifetimes and emission within the optical window. Here, we…”
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    Journal Article
  8. 8

    General Approach to Direct Measurement of the Hydration State of Coordination Complexes in the Gas Phase: Variable Temperature Mass Spectrometry by Racow, Emily E, Kreinbihl, John J, Cosby, Alexia G, Yang, Yi, Pandey, Apurva, Boros, Eszter, Johnson, Christopher J

    Published in Journal of the American Chemical Society (18-09-2019)
    “…The formation of ternary aqua complexes of metal-based diagnostics and therapeutics is closely correlated to their in vivo efficacy but approaches to quantify…”
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    Journal Article
  9. 9

    Evolution of Atomic-Level Structure in Sub-10 Nanometer Iron Oxide Nanocrystals: Influence on Cation Occupancy and Growth Rates by Cooper, Susan R, Candler, Randall O, Cosby, Alexia G, Johnson, Darren W, Jensen, Kirsten M. Ø, Hutchison, James E

    Published in ACS nano (26-05-2020)
    “…Spinel iron oxide nanocrystals (NCs) have been reported to have atomic-level core and surface structural features that differ from those of the bulk material…”
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    Journal Article
  10. 10
  11. 11

    Siderocalin fusion proteins enable a new Y/Y theranostic approach by Cosby, Alexia G, Arino, Trevor, Bailey, Tyler A, Buerger, Matthew, Woods, Joshua J, Aguirre Quintana, Luis M, Alvarenga Vasquez, Jennifer V, Wacker, Jennifer N, Gaiser, Alyssa N, Strong, Roland K, Abergel, Rebecca J

    Published in RSC chemical biology (03-08-2023)
    “…The mammalian protein siderocalin binds bacterial siderophores and their iron complexes through cation-π and electrostatic interactions, but also displays high…”
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    Journal Article
  12. 12

    Siderocalin fusion proteins enable a new 86 Y/ 90 Y theranostic approach by Cosby, Alexia G, Arino, Trevor, Bailey, Tyler A, Buerger, Matthew, Woods, Joshua J, Aguirre Quintana, Luis M, Alvarenga Vasquez, Jennifer V, Wacker, Jennifer N, Gaiser, Alyssa N, Strong, Roland K, Abergel, Rebecca J

    Published in RSC chemical biology (03-08-2023)
    “…The mammalian protein siderocalin binds bacterial siderophores and their iron complexes through cation-π and electrostatic interactions, but also displays high…”
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    Journal Article
  13. 13

    Siderocalin fusion proteins enable a new 86Y/90Y theranostic approach by Cosby, Alexia G, Arino, Trevor, Bailey, Tyler A, Buerger, Matthew, Woods, Joshua J, Aguirre Quintana, Luis M, Alvarenga Vasquez, Jennifer V, Wacker, Jennifer N, Gaiser, Alyssa N, Strong, Roland K, Abergel, Rebecca J

    Published in RSC chemical biology (03-08-2023)
    “…The mammalian protein siderocalin binds bacterial siderophores and their iron complexes through cation-π and electrostatic interactions, but also displays high…”
    Get full text
    Journal Article
  14. 14

    Cherenkov Radiation‐Mediated In Situ Excitation of Discrete Luminescent Lanthanide Complexes by Cosby, Alexia G., Ahn, Shin Hye, Boros, Eszter

    Published in Angewandte Chemie (19-11-2018)
    “…Lanthanide luminescence, while ideal for in vivo applications owing to sharp emission bands within the optical window, requires high‐intensity,…”
    Get full text
    Journal Article
  15. 15

    Accessing lanthanide-based, illuminated optical turn-on probes by modulation of the antenna triplet state energy by Cosby, Alexia G, Woods, Joshua J, Nawrocki, Patrick, Sørensen, Thomas J, Wilson, Justin J, Boros, Eszter

    Published in Chemical science (Cambridge) (14-07-2021)
    “…Luminescent lanthanides possess ideal properties for biological imaging, including long luminescent lifetimes and emission within the optical window. Here, we…”
    Get full text
    Journal Article