Search Results - "Coppolino, Giusy"

Differential local tissue permissiveness influences the final fate of GPR17‐expressing oligodendrocyte precursors in two distinct models of demyelination by Coppolino, Giusy T., Marangon, Davide, Negri, Camilla, Menichetti, Gianluca, Fumagalli, Marta, Gelosa, Paolo, Dimou, Leda, Furlan, Roberto, Lecca, Davide, Abbracchio, Maria P.

“…Promoting remyelination is recognized as a novel strategy to foster repair in neurodegenerative demyelinating diseases, such as multiple sclerosis. In this…”
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Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis by Parravicini, Chiara, Lecca, Davide, Marangon, Davide, Coppolino, Giusy Tindara, Daniele, Simona, Bonfanti, Elisabetta, Fumagalli, Marta, Raveglia, Luca, Martini, Claudia, Gianazza, Elisabetta, Trincavelli, Maria Letizia, Abbracchio, Maria P, Eberini, Ivano

“…The GPR17 receptor, expressed on oligodendroglial precursors (OPCs, the myelin producing cells), has emerged as an attractive target for a pro-myelinating…”
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MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis by Lecca, Davide, Marangon, Davide, Coppolino, Giusy T., Méndez, Aida Menéndez, Finardi, Annamaria, Costa, Gloria Dalla, Martinelli, Vittorio, Furlan, Roberto, Abbracchio, Maria P.

“…In the mature central nervous system (CNS), oligodendrocytes provide support and insulation to axons thanks to the production of a myelin sheath. During their…”
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Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis by Paladini, Maria Serena, Marangon, Davide, Rossetti, Andrea C., Guidi, Alice, Coppolino, Giusy T., Negri, Camilla, Spero, Vittoria, Abbracchio, Maria Pia, Lecca, Davide, Molteni, Raffaella

“…One of the most substantial and established environmental risk factors for neurological and psychiatric disorders is stress exposure, whose detrimental…”
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Adipokines and Systemic Lupus Erythematosus: Relationship with Metabolic Syndrome and Cardiovascular Disease Risk Factors by VADACCA, Marta, MARGIOTTA, Domenico, RIGON, Amelia, CACCIAPAGLIA, Fabio, COPPOLINO, Giusy, AMOROSO, Antonio, AFELTRA, Antonella

“…Objective. To study concentrations of adipokines in patients with systemic lupus erythematosus (SLE) and the relationship among adipokines, the metabolic…”
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Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine by Fumagalli, Marta, Lecca, Davide, Coppolino, Giusy T, Parravicini, Chiara, Abbracchio, Maria P

“…In 2006, cells heterologously expressing the "orphan" receptor GPR17 were shown to acquire responses to both uracil nucleotides and cysteinyl-leukotrienes, two…”
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Percutaneous ultrasound-guided ablation of BW7756-hepatoma using ethanol or acetic acid in a rat model by Zardi, Enrico M, Borzomati, Domenico, Cacciapaglia, Fabio, Picardi, Antonio, Valeri, Sergio, Bianchi, Antonella, Galeotti, Tommaso, Coppolino, Giusy, Coppola, Roberto, Afeltra, Antonella

“…To compare tumor necrosis in hepatoma induced in rats by a single percutaneous injection of ethanol (PEI) or acetic acid (PAI). BW7756 hepatomas of 1 mm3 were…”
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Differential local tissue permissiveness influences the final fate of GPR 17‐expressing oligodendrocyte precursors in two distinct models of demyelination by Coppolino, Giusy T., Marangon, Davide, Negri, Camilla, Menichetti, Gianluca, Fumagalli, Marta, Gelosa, Paolo, Dimou, Leda, Furlan, Roberto, Lecca, Davide, Abbracchio, Maria P.

“…Abstract Promoting remyelination is recognized as a novel strategy to foster repair in neurodegenerative demyelinating diseases, such as multiple sclerosis. In…”
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A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights by Parravicini, Chiara, Daniele, Simona, Palazzolo, Luca, Trincavelli, Maria Letizia, Martini, Claudia, Zaratin, Paola, Primi, Roberto, Coppolino, Giusy, Gianazza, Elisabetta, Abbracchio, Maria P., Eberini, Ivano

“…Recent data and publications suggest a promiscuous behaviour for GPR17, a class-A GPCR operated by different classes of ligands, such as uracil nucleotides,…”
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Low levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 in patients with newly diagnosed type 1 diabetes by Pozzilli, P, Manfrini, S, Crinò, A, Picardi, A, Leomanni, C, Cherubini, V, Valente, L, Khazrai, M, Visalli, N

“…An epidemiological retrospective study and a recent prospective study from Finland have both concluded that vitamin D3 supplementation at birth protects…”
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Biokinetics of buccal spray insulin in patients with type 1 diabetes by Pozzilli, Paolo, Manfrini, Silvia, Costanza, Flavia, Coppolino, Giusy, Cavallo, Maria Gisella, Fioriti, Elvira, Modi, Pankaj

“…To evaluate the metabolic effect of buccal spray insulin compared with subcutaneous regular insulin in patients with type 1 diabetes. This study compared…”
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Pancreatic scintigraphy with 99mTc-interleukin-2 at diagnosis of type 1 diabetes and after 1 year of nicotinamide therapy by Chianelli, M., Parisella, M. G., Visalli, N., Mather, S. J., D'Alessandria, C., Pozzilli, P., Signore, A.

“…Background To evaluate the clinical utility of pancreatic scintigraphy with 99mTc‐interleukin‐2 to identify Type 1 diabetic patients with pancreatic…”
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A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX) by CRINO, A, SCHIAFFINI, R, MATTEOLI, M. C, PATERA, I. P, MANCA BITTI, M. L, BIZZARRI, C, POZZILLION, P, MANFRINI, S, MESTURINO, C, VISALLI, N, BERETTA ANGUISSOLA, G, SURACI, C, PITOCCO, D, SPERA, S, CORBI, S

“…Various adjuvant therapies have been introduced along with intensive insulin therapy in patients with recent onset type 1 diabetes. Nicotinamide (NA),…”
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The adjunctive role of antiphospholipid antibodies in systemic lupus erythematosus cardiac involvement by AMOROSO, A, CACCIAPAGLIA, F, DE CASTRO, S, BATTAGLIESE, A, COPPOLINO, G, GALLUZZO, S, VADACCA, M, AFELTRA, A

“…To evaluate the prevalence of cardiac alterations by trans thoracic echocardiography (TTE) and the possible role of aPLs in determining heart damage in SLE…”
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A 2-year pilot trial of continuous subcutaneous insulin infusion versus intensive insulin therapy in patients with newly diagnosed type 1 diabetes (IMDIAB 8) by Pozzilli, Paolo, Crinò, Antonino, Schiaffini, Riccardo, Manfrini, Silvia, Fioriti, Elvira, Coppolino, Giusy, Pitocco, Dario, Visalli, Natalia, Corbi, Stefania, Spera, Sabrina, Suraci, Concetta, Cervoni, Marco, Matteoli, Maria C, Patera, I Patrizia, Ghirlanda, Giovanni

“…In a pilot study, the metabolic effects of continuous subcutaneous insulin infusion (CSII) versus intensive subcutaneous insulin therapy (ISIT) started at…”
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Hepatitis B Vaccine Associated with an Increased Risk of Type 1 Diabetes in Italy by POZZILLI, PAOLO, VISALLI, NATALIA, COPPOLINO, GIUSY, CLASSEN, DAVID C, CLASSEN, JOHN B

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T Cell Lines to Bovine [Beta]-Casein in Type 1 Diabetes by MONETINI, LAURA, CAVALLO, MARIA G, STEFANINI, LAVINIA, COPPOLINO, GIUSY, WALK, TILMANN, JUNG, GUNTHER, POZZILLI, PAOLO

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Inhaled insulin in type 1 diabetes by Gisella Cavallo, Maria, Coppolino, Giusy, Romeo, Stefano, Pozzilli, Paolo

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Inhaled insulin in type 1 diabetes by Baker, EH, Philips, BJ

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