Search Results - "Coppock, Matthew B"

Peptide-Based Capture of Chikungunya Virus E2 Protein Using Porous Silicon Biosensor by Layouni, Rabeb, Cao, Tengfei, Coppock, Matthew B, Laibinis, Paul E, Weiss, Sharon M

“…The detection of pathogens presents specific challenges in ensuring that biosensors remain operable despite exposure to elevated temperatures or other extreme…”
Get full text

A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen by Farrow, Blake, Hong, Sung A, Romero, Errika C, Lai, Bert, Coppock, Matthew B, Deyle, Kaycie M, Finch, Amethist S, Stratis-Cullum, Dimitra N, Agnew, Heather D, Yang, Sung, Heath, James R

“…We report on a robust and sensitive approach for detecting protective antigen (PA) exotoxin from Bacillus anthracis in complex media. A peptide-based capture…”
Get full text

The application of ( Z)-3-aryl-3-haloenoic acids to the synthesis of ( Z)-5-benzylidene-4-arylpyrrol-2(5 H)-ones by Gupton, John T., Telang, Nakul, Banner, Edith J., Kluball, Emily J., Hall, Kayleigh E., Finzel, Kara L., Jia, Xin, Bates, Spencer R., Welden, R. Scott, Giglio, Benjamin C., Eaton, James E., Barelli, Peter J., Firich, Lauren T., Stafford, John A., Coppock, Matthew B., Worrall, Eric F., Kanters, Rene P.F., Keertikar, Kerry, Osterman, Rebecca

“…Studies directed at the synthesis of ( Z)-5-benzylidene-4-arylpyrrol-2(5 H)-ones from ( Z)-3-aryl-3-haloenoic acids are described. The successful strategy…”
Get full text

A universal method for the functionalization of dyed magnetic microspheres with peptides by Coppock, Matthew B., Stratis-Cullum, Dimitra N.

“…•Bead functionalization is capable with any peptide regardless of sequence.•Universal incorporation through a ‘click’ chemistry strategy.•1000 Da PEG linker…”
Get full text

Protein-Catalyzed Capture Agents by Agnew, Heather D, Coppock, Matthew B, Idso, Matthew N, Lai, Bert T, Liang, JingXin, McCarthy-Torrens, Amy M, Warren, Carmen M, Heath, James R

“…Protein-catalyzed capture agents (PCCs) are synthetic and modular peptide-based affinity agents that are developed through the use of single-generation in situ…”
Get full text

A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands by Das, Samir, Nag, Arundhati, Liang, JingXin, Bunck, David N., Umeda, Aiko, Farrow, Blake, Coppock, Matthew B., Sarkes, Deborah A., Finch, Amethist S., Agnew, Heather D., Pitram, Suresh, Lai, Bert, Yu, Mary Beth, Museth, A. Katrine, Deyle, Kaycie M., Lepe, Bianca, Rodriguez-Rivera, Frances P., McCarthy, Amy, Alvarez-Villalonga, Belen, Chen, Ann, Heath, John, Stratis-Cullum, Dimitra N., Heath, James R.

“…We describe a general synthetic strategy for developing high‐affinity peptide binders against specific epitopes of challenging protein biomarkers. The epitope…”
Get full text

Correction to A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen by Farrow, Blake, Hong, Sung A, Romero, Errika C, Lai, Bert, Coppock, Matthew B, Deyle, Kaycie M, Finch, Amethist S, Stratis-Cullum, Dimitra N, Agnew, Heather D, Yang, Sung, Heath, James R

Get full text

Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications by Coppock, Matthew B., Warner, Candice R., Dorsey, Brandi, Orlicki, Joshua A., Sarkes, Deborah A., Lai, Bert T., Pitram, Suresh M., Rohde, Rosemary D., Malette, Jacquie, Wilson, Jeré A., Kearney, Paul, Fang, Kenneth C., Law, Scott M., Candelario, Sherri L., Farrow, Blake, Finch, Amethist S., Agnew, Heather D., Heath, James R., Stratis‐Cullum, Dimitra N.

“…We report on peptide‐based ligands matured through the protein catalyzed capture (PCC) agent method to tailor molecular binders for in vitro…”
Get full text

Assembly of a Trifunctional Artificial Peptide Into an Anti-Parallel Duplex with Three Cu(II) Cross-links by Coppock, Matthew B, Miller, James R, Williams, Mary Elizabeth

“…Analogous to self-assembly in natural DNA or proteins, we describe the synthesis of a heterofunctional artificial tripeptide that self-assembles into an…”
Get full text

A novel discovery, maturation, and assay integration approach for the development of ruggedized multi-valent capture receptors exemplified against the chikungunya virus E2 protein by Coppock, Matthew B., Hurley, Margaret, Jones, Curtis, Erickson, Daniela, Stratis-Cullum, Dimitra N.

“…This work reports on the development of synthetic, thermally stable receptors using a novel discovery and multi-valent maturation strategy exemplified against…”
Get full text

Cooperative Assembly of Zn Cross-Linked Artificial Tripeptides with Pendant Hydroxyquinoline Ligands by Zhang, Meng, Gallagher, Joy A, Coppock, Matthew B, Pantzar, Lisa M, Williams, Mary Elizabeth

“…An artificial peptide with three pendant hydroxyquinoline (hq) ligands on a palindromic backbone was designed and used to form multimetallic assemblies…”
Get full text

Cu(II) cross-linked antiparallel dipeptide duplexes using heterofunctional ligand-substituted aminoethylglycine by Coppock, Matthew B, Kapelewski, Matthew T, Youm, Hye Won, Levine, Lauren A, Miller, James R, Myers, Carl P, Williams, Mary Elizabeth

“…Two artificial dipeptides containing both a pendant monodentate (pyridine (py)) and tridentate (terpyridine (tpy) or phenyl terpyridine (varphi-tpy)) ligand on…”
Get full text

The application of vinylogous iminium salt derivatives and microwave accelerated Vilsmeier–Haack reactions to efficient relay syntheses of the polycitone and storniamide natural products by Gupton, John T., Banner, Edith J., Sartin, Melissa D., Coppock, Matthew B., Hempel, Jonathan E., Kharlamova, Anastasia, Fisher, Daniel C., Giglio, Ben C., Smith, Kristin L., Keough, Matt J., Smith, Timothy M., Kanters, Rene P.F., Dominey, Raymond N., Sikorski, James A.

“…Studies directed at the synthesis of polycitone and storniamide natural products via vinylogous iminium salts and microwave accelerated Vilsmeier–Haack…”
Get full text

A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands by Das, Samir, Nag, Arundhati, Liang, JingXin, Bunck, David N., Umeda, Aiko, Farrow, Blake, Coppock, Matthew B., Sarkes, Deborah A., Finch, Amethist S., Agnew, Heather D., Pitram, Suresh, Lai, Bert, Yu, Mary Beth, Museth, A. Katrine, Deyle, Kaycie M., Lepe, Bianca, Rodriguez-Rivera, Frances P., McCarthy, Amy, Alvarez-Villalonga, Belen, Chen, Ann, Heath, John, Stratis-Cullum, Dimitra N., Heath, James R.

“…We describe a general synthetic strategy for developing high‐affinity peptide binders against specific epitopes of challenging protein biomarkers. The epitope…”
Get full text

A Single Multiomics Transistor for Electronic Detection of SARS‐Cov2 Variants Antigen and Viral RNA Without Amplification by Ban, Deependra K., Hajian, Reza, Winton, Alexander J., Eom, Ryan, Gupta, Ankit, Kane, Alexander A., Liu, Sanchao, Sampath, Rangarajan, Farrell, Michael L., Coppock, Matthew B., Goldsmith, Brett, Aran, Kiana

“…The SARS‐CoV‐2 pandemic caused a public health crisis throughout the world and highlighted the need for rapid and sensitive testing as a countermeasure. A…”
Get full text

A Single Multiomics Transistor for Electronic Detection of SARS‐Cov2 Variants Antigen and Viral RNA Without Amplification (Adv. Mater. Technol. 11/2023) by Ban, Deependra K., Hajian, Reza, Winton, Alexander J., Eom, Ryan, Gupta, Ankit, Kane, Alexander A., Liu, Sanchao, Sampath, Rangarajan, Farrell, Michael L., Coppock, Matthew B., Goldsmith, Brett, Aran, Kiana

“…Graphene Field‐Effect Transistors In article 2201945, Matthew B. Coppock, Brett Goldsmith, Kiana Aran, and co‐workers develop a single multiomics test for…”
Get full text

Cu II Cross-Linked Antiparallel Dipeptide Duplexes Using Heterofunctional Ligand-Substituted Aminoethylglycine by Coppock, Matthew B., Kapelewski, Matthew T., Youm, Hye Won, Levine, Lauren A., Miller, James R., Myers, Carl P., Williams, Mary Elizabeth

Get full text

The application of vinylogous iminium salt derivatives to an efficient synthesis of the pyrrole containing alkaloids Rigidin and Rigidin E by Gupton, John T., Banner, Edith J., Scharf, Austin B., Norwood, Bradley K., Kanters, Rene P.F., Dominey, Raymond N., Hempel, Jonathan E., Kharlamova, Anastasia, Bluhn-Chertudi, Itta, Hickenboth, Charles R., Little, Barrett A., Sartin, Melissa D., Coppock, Matthew B., Krumpe, Keith E., Burnham, Bruce S., Holt, Herman, Du, Karen X., Keertikar, Kartik M., Diebes, Anthony, Ghassemi, Shahnaz, Sikorski, James A.

“…Studies directed on the synthesis of the pyrrole containing marine natural products Rigidin and Rigidin E via vinylogous iminium salts are described. The…”
Get full text

Self-complementary heterofunctional and chiral artificial oligopeptides substituted with metal binding ligands by Coppock, Matthew B

“…The design and synthesis of molecules that mimic the assembly and molecular recognition properties of natural systems is a strategy that can be utilized to…”
Get full text

Towards Army Relevant Sensing with Integrated Molecularly Imprinted Polymer Photonic (IMIPP) Devices by Farrell, Mikella E., Coppock, Matthew B., Holthoff, Ellen L., Pellegrino, Paul M., Bickford, Justin R., Cho, Pak S.

“…Development of a sensor consisting of a molecularly imprinted polymer integrated onto a photonic chip is discussed. This sensor has applications for threat…”
Get full text