Search Results - "Coppen, S."

Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients – Potential markers of ventricular arrhythmia by Sawhney, V, Campbell, N.G, Brouilette, S.W, Coppen, S.R, Harbo, M, Baker, V, Ikebe, C, Shintani, Y, Hunter, R.J, Dhinoja, M, Johnston, A, Earley, M.J, Sporton, S, Bendix, L, Suzuki, K, Schilling, R.J

“…Abstract Background Implantable cardioverter defibrillators (ICDs) reduce mortality in patients with ischaemic cardiomyopathy at high risk of ventricular…”
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Connexin45 Expression Is Preferentially Associated With the Ventricular Conduction System in Mouse and Rat Heart by Coppen, Steven R, Dupont, Emmanuel, Rothery, Stephen, Severs, Nicholas J

“…Cardiac myocytes are electrically coupled by gap junctions, clusters of low-resistance intercellular channels composed of connexins. Variations in the…”
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Individual Gap Junction Plaques Contain Multiple Connexins in Arterial Endothelium by Yeh, Hung-I, Rothery, Stephen, Dupont, Emmanuel, Coppen, Steven R, Severs, Nicholas J

“…Gap-junctional intercellular communication in endothelial cells is implicated in the coordination of growth, migration, and vasomotor responses. Up to 3…”
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Impedance measurements and connexin expression in human detrusor muscle from stable and unstable bladders by Sui, G.P., Coppen, S.R., Dupont, E., Rothery, S., Gillespie, J., Newgreen, D., Severs, N.J., Fry, C.H.

“…Three of this month's Scientific Discovery papers highlight the importance of collaboration in delivering high quality scientific research. As scientific…”
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Enhanced efficiency of superoxide dismutase-induced cardioprotection by retrograde intracoronary administration by FUKUSHIMA, Satsuki, COPPEN, Steven R, VARELA-CARVER, Anabel, BRINDLEY, Gemma, YAMAHARA, Kenichi, SARATHCHANDRA, Padmini, YACOUB, Magdi H, SUZUKI, Ken

“…We hypothesized that modification of the infusion route may improve the efficiency of superoxide dismutase (SOD)-induced cardioprotection against reperfusion…”
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Turbulence characteristics along the path of a heavy particle by Coppen, S.W., Manno, V.P., Rogers, C.B.

“…The turbulence along the path of a particle in an isotropic turbulent flow is investigated using direct numerical simulation. The turbulence is simulated using…”
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Measurement of fluid turbulence along the path of a heavy particle in a backward-facing step flow by McAndrew, D, Coppen, S, Rogers, C.B

“…To accurately model the motion of a solid particle in a turbulent air flow, characteristics of the fluid turbulence in the particle-Lagrangian reference frame…”
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Connexin45 is the first connexin to be expressed in the central conduction system of the mouse heart by Coppen, Steven R, Gourdie, Robert G, Severs, Nicholas J

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CONGENITAL MYOPATHIES: GENERAL AND RYR1: P.47ASC1-related myopathy is associated with defects in myoblast proliferation and muscle growth: defining the phenotypic spectrum and understanding the pathogenesis of an emerging congenital myopathy by Duband-Goulet, I., Catervi, F., Cabet, E., Davignon, L., Genetti, C., Gidaro, T., Koparir, A., Coppen, S., Pierce-Hoffman, E., Beggs, A., Servais, L., Ferreiro, A.

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CONGENITAL MYOPATHIES: GENERAL AND RYR1 by Duband-Goulet, I., Catervi, F., Cabet, E., Davignon, L., Genetti, C., Gidaro, T., Koparir, A., Coppen, S., Pierce-Hoffman, E., Beggs, A., Servais, L., Ferreiro, A.

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Altered Connexin Expression in Human Congestive Heart Failure by Dupont, Emmanuel, Matsushita, Tsutomu, Kaba, Riyaz A., Vozzi, Cristina, Coppen, Steven R., Khan, Natasha, Kaprielian, Raffi, Yacoub, Magdi H., Severs, Nicholas J.

“…Congestive heart failure is associated with a high risk of life-threatening ventricular re-entrant arrhythmias. Down-regulation of the principal gap-junctional…”
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Remodelling of gap junctions and connexin expression in heart disease by Severs, Nicholas J., Dupont, Emmanuel, Coppen, Steven R., Halliday, Deborah, Inett, Edward, Baylis, Daniel, Rothery, Stephen

“…Different combinations and relative quantities of three connexins—connexin43, connexin40 and connexin45—are expressed in different subsets of cardiomyocyte. In…”
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The gap-junctional protein connexin40 is elevated in patients susceptible to postoperative atrial fibrillation by DUPONT, Emmanuel, KO, Yu-Shien, ROTHERY, Stephen, COPPEN, Steven R, BAGHAI, Max, HAW, Marcus, SEVERS, Nicholas J

“…Atrial fibrillation (AF), a cardiac arrhythmia arising from atrial re-entrant circuits, is a common complication after cardiac surgery, but the proarrhythmic…”
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Chamber-related Differences in Connexin Expression in the Human Heart by Vozzi, Cristina, Dupont, Emmanuel, Coppen, Steven R., Yeh, Hung-I, Severs, Nicholas J.

“…Electrical coupling in the heart is mediated by gap junctions, aggregates of cell-to-cell channels composed of connexins. The principal cardiac gap-junctional…”
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Immunocytochemical analysis of connexin expression in the healthy and diseased cardiovascular system by Severs, Nicholas J., Rothery, Stephen, Dupont, Emmanuel, Coppen, Steven R., Yeh, Hung-I, Ko, Yu-Shien, Matsushita, Tsutomu, Kaba, Riyaz, Halliday, Deborah

“…Gap junctions play essential roles in the normal function of the heart and arteries, mediating the spread of the electrical impulse that stimulates…”
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Replacement of Connexin40 by Connexin45 in the Mouse: Impact on Cardiac Electrical Conduction by Alcoléa, Sébastien, Jarry-Guichard, Thérèse, de Bakker, Jacques, Gonzàlez, Daniel, Lamers, Wouter, Coppen, Steven, Barrio, Luis, Jongsma, Habo, Gros, Daniel, van Rijen, Harold

“…ABSTRACT—Gap junction channels, required for the propagation of cardiac impulse, are intercellular structures composed of connexins (Cx). Cx43, Cx40, and Cx45…”
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Connexin45 (α6) expression delineates an extended conduction system in the embryonic and mature rodent heart by Coppen, Steven R., Severs, Nicholas J., Gourdie, Robert G.

“…We previously demonstrated that α6 (Cx45), one of the three connexins of the mammalian myocardium, is preferentially expressed in the peripheral portion of the…”
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Connexin45, a Major Connexin of the Rabbit Sinoatrial Node, Is Co-expressed with Connexin43 in a Restricted Zone at the Nodal–Crista Terminalis Border by Coppen, Steven R, Kodama, Itsuo, Boyett, Mark R, Dobrzynski, Halina, Takagishi, Yoshiko, Honjo, Haruo, Yeh, Hung-I, Severs, Nicholas J

“…The pacemaker of the heart, the sinoatrial (SA) node, is characterized by unique electrical coupling properties. To investigate the contribution of gap…”
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Regional Differentiation of Desmin, Connexin43, and Connexin45 Expression Patterns in Rat Aortic Smooth Muscle by Ko, Yu-Shien, Coppen, Steven R, Dupont, Emmanuel, Rothery, Stephen, Severs, Nicholas J

“…Abstract —The gap-junctional protein, connexin43, is differentially expressed in vascular smooth muscle cells (SMCs) according to phenotype. Previous studies…”
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Direct effects of apelin on cardiomyocyte contractility and electrophysiology by Farkasfalvi, Klára, Stagg, Mark A., Coppen, Steven R., Siedlecka, Urszula, Lee, Joon, Soppa, Gopal K., Marczin, Nándor, Szokodi, István, Yacoub, Magdi H., Terracciano, Cesare M.N.

“…Apelin, the ligand for the angiotensin receptor like-1, has been implicated in the pathogenesis of atrial fibrillation and heart failure. However, it is…”
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