Search Results - "Copeland, N. G"

Structure‐function integrity of the adult hippocampus depends on the transcription factor Bcl11b/Ctip2 by Simon, R., Baumann, L., Fischer, J., Seigfried, F. A., De Bruyckere, E., Liu, P., Jenkins, N. A., Copeland, N. G., Schwegler, H., Britsch, S.

“…The dentate gyrus is one of the only two brain regions where adult neurogenesis occurs. Throughout life, cells of the neuronal stem cell niche undergo…”
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Direct interaction of microtubule- and actin-based transport motors by Huang, J. D., Brady, S. T., Richards, B. W., Stenolen, D., Resau, J. H., Copeland, N. G., Jenkins, N. A.

“…The microtubule network is thought to be used for long-range transport of cellular components in animal cells whereas the actin network is proposed to be used…”
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Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development by Nishinakamura, R, Matsumoto, Y, Nakao, K, Nakamura, K, Sato, A, Copeland, N G, Gilbert, D J, Jenkins, N A, Scully, S, Lacey, D L, Katsuki, M, Asashima, M, Yokota, T

“…SALL1 is a mammalian homolog of the Drosophila region-specific homeotic gene spalt ( sal ); heterozygous mutations in SALL1 in humans lead to Townes-Brocks…”
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TLR6: A novel member of an expanding Toll-like receptor family by Takeuchi, O., Kawai, T., Sanjo, H., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Takeda, K., Akira, S.

“…Drosophila Toll protein is shown to activate the innate immune system in adult and regulate the dorsoventral patterning in the developing embryo. Recently,…”
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Intranuclear Inclusions and Neuritic Aggregates in Transgenic Mice Expressing a Mutant N-Terminal Fragment of Huntingtin by Schilling, Gabriele, Becher, Mark W., Sharp, Alan H., Jinnah, Hyder A., Duan, Kui, Kotzuk, Joyce A., Slunt, Hilda H., Ratovitski, Tamara, Cooper, Jillian K., Jenkins, Nancy A., Copeland, Neal G., Price, Donald L., Ross, Christopher A., Borchelt, David R.

“…Huntington's disease (HD) is an inherited, neurodegenerative disorder caused by the expansion of a glutamine repeat in the N-terminus of the huntingtin…”
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ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions by Bruijn, L.I., Becher, M.W., Lee, M.K., Anderson, K.L., Jenkins, N.A., Copeland, N.G., Sisodia, S.S., Rothstein, J.D., Borchelt, D.R., Price, D.L., Cleveland, D.W.

“…High levels of familial Amyotrophic Lateral Sclerosis (ALS)-linked SOD1 mutants G93A and G37R were previously shown to mediate disease in mice through an…”
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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues by BRANNAN, C. I, PERKINS, A. S, VOGEL, K. S, RATNER, N, NORDLUND, M. L, REID, S. W, BUCHBERG, A. M, JENKINS, N. A, PARADA, L. F, COPELAND, N. G

“…The neurofibromatosis (NF1) gene shows significant homology to mammalian GAP and is an important regulator of the ras signal transduction pathway. To study the…”
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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer by Fishel, R, Lescoe, M K, Rao, M R, Copeland, N G, Jenkins, N A, Garber, J, Kane, M, Kolodner, R

“…We have identified a human homolog of the bacterial MutS and S. cerevisiae MSH proteins, called hMSH2. Expression of hMSH2 in E. coli causes a dominant mutator…”
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Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity by Tsui, CC, Copeland, NG, Gilbert, DJ, Jenkins, NA, Barnes, C, Worley, PF

“…Stimulus-linked RNA and protein synthesis is required for establishment of long-term neuroplasticity. To identify molecular mechanisms underlying long-term…”
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The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase by LUETTEKE, N. C, PHILLIPS, H. K, QIU, T. H, COPELAND, N. G, EARP, H. S, JENKINS, N. A, LEE, D. C

“…Mice harboring the waved-1 (wa-1) and waved-2 (wa-2) mutations exhibit skin and eye abnormalities that are strikingly similar to those of TGF-alpha-deficient…”
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Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins by XIAO-HONG SUN, COPELAND, N. G, JENKINS, N. A, BALTIMORE, D

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity by Fletcher, Colin F., Tottene, Angelita, Lennon, Vanda A., Wilson, Scott M., Dubel, Stefan J., Paylor, Richard, Hosford, David A., Tessarollo, Lino, McEnery, Maureen W., Pietrobon, Daniela, Copeland, Neal G., Jenkins, Nancy A.

“…ABSTRACT P/Q‐type voltage‐dependent calcium channel CACNA1A mutations cause dominantly inherited migraine, episodic ataxia, and cerebellar atrophy in humans…”
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Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein by Hodgkinson, C A, Moore, K J, Nakayama, A, Steingrímsson, E, Copeland, N G, Jenkins, N A, Arnheiter, H

“…Mice with mutations at the microphthalmia (mi) locus have some or all of the following defects: loss of pigmentation, reduced eye size, failure of secondary…”
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Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK‐STAT5 pathway by Yoshimura, A., Ichihara, M., Kinjyo, I., Moriyama, M., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Hara, T., Miyajima, A.

“…Oncostatin M (OSM) is a member of the interleukin‐6 (IL6)‐related cytokine subfamily that includes IL6, IL11, leukemia inhibitory factor (LIF), ciliary…”
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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis by Watanabe-Fukunaga, Rie, Brannan, Camilynn I, Copeland, Neal G, Jenkins, Nancy A, Nagata, Shigekazu

“…Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has structural homology with a…”
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Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme by Kumar, S, Kinoshita, M, Noda, M, Copeland, N G, Jenkins, N A

“…By subtraction cloning we previously identified a set of mouse genes (named Nedd1 through Nedd10) with developmentally down-regulated expression in brain. We…”
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A Receptor Tyrosine Kinase cDNA Isolated from a Population of Enriched Primitive Hematopoietic Cells and Exhibiting Close Genetic Linkage to C-kit by Matthews, William, Jordan, Craig T., Gavin, Marc, Jenkins, Nancy A., Copeland, Neal G., Lemischka, Ihor R.

“…We have cloned a receptor tyrosine kinase cDNA, designated fetal liver kinase 1 (Flk-1), from mouse cell populations enriched for hematopoietic stem and…”
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Leukaemia disease genes: large-scale cloning and pathway predictions by Copeland, Neal G, Li, Jiayin, Shen, Haifa, Himmel, Karen L, Dupuy, Adam J, Largaespada, David A, Nakamura, Takuro, Shaughnessy, John D, Jenkins, Nancy A

“…Retroviral insertional mutagenesis in BXH2 and AKXD recombinant inbred mice induces a high incidence of myeloid or B- and T-cell leukaemia and the proviral…”
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A mouse model for Prader-Willi syndrome imprinting-centre mutations by Yang, Tao, Adamson, Todd E, Resnick, James L, Leff, Stuart, Wevrick, Rachel, Francke, Uta, Jenkins, Nancy A, Copeland, Neal G, Brannan, Camilynn I

“…Imprinting in the 15q11-q13 region involves an 'imprinting centre' (IC), mapping in part to the promoter and first exon of SNRPN. Deletion of this IC abolishes…”
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Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins by Chang, Ching-Pin, Jacobs, Yakop, Nakamura, Takuro, Jenkins, Nancy A., Copeland, Neal G., Cleary, Michael L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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